Protein Alignment CG7333 and slc22a4

DIOPT Version :10

• Sequence 1: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_957143.1
• Gene: slc22a4 / 393822
• ZFINID: ZDB-GENE-040426-1517
• Length: 553
• Species: Danio rerio
• Alignment Length: 560
• Identity: 155/560 - (27%)
• Similarity: 243/560 - (43%)
• Gaps: 89/560 - (15%)

  Fly     2 DFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITF---TPEHWCFHADLNGLSVEGIR 63
            |:..:....|.:|.||:.:.|....:.:...   |....|.|   ||.|.|...:...:|
Zfish     3 DYDDITSFLGTWGPFQLTVFLALAISILPNG---FVGLYIVFVGDTPAHECLIPEQINIS----- 59

  Fly    64 SVYEN-----------ISASSCTPL-------LGVVNGTGVVSTN------RKC-RNWIFNRESG 103
            ||:.:           :..|||:..       |.::|.|..|..|      ..| ..|.:::|..
Zfish    60 SVWRDAAIPTQMQDGVLKRSSCSRYRLDTLRQLSMLNYTPNVEVNLSQIETEPCVDGWSYSQEFY 124

  Fly   104 YESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSL--LMATLCGATGDFIT 166
            ..:|.||...||::.:...:..|.:|.|.:|||.:.|.:||:.||.|.|  :||.      ..||
Zfish   125 QSTIVTEWDLVCEREYKGPLTSSIYFCGVLVGTFLSGQMSDRYGRRPVLFTMMAL------QTIT 183

  Fly   167 SFVHTL--PWFAFSR--FMSGLSTDTMYYLMYILVFEYLSPKSRT-FGLNIILAVFYCFGL--MT 224
            ..:...  .|..||.  |..|.|..:.|.:.|:|..|.|||.||. ||   .|.||...|:  |.
Zfish   184 ILIQMFSPSWEVFSAIYFFVGFSGFSNYVVAYVLGSEILSPASRVLFG---SLGVFMGSGIGQMF 245

  Fly   225 SPWAAIWIGNWRRYLWLASLPAL-GVLIYP--FLICESAQWLLTKRKYDDAVICLKKVAKFNRRH 286
            .|.||.:|.:||   ||....|| |:|.:|  :.|.||.:|||::.:..:|...|::.|:.||..
Zfish   246 FPLAAYFIRSWR---WLVLTNALTGLLYFPLWWFIPESPRWLLSQGRTAEAEAVLRRAAEKNRVT 307

  Fly   287 VEESVF------DEFVKYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKS---VIITLS 342
            ..|.:|      :...|..::..:.|...|.:.               ..|:|:.|   ::||:|
Zfish   308 APEVIFSSSEIEEAAKKRIQKHSILDILSNCNA---------------VSTILICSLLWMVITMS 357

  Fly   343 CDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIA 407
            ...:..|...|..:|:..|..:::|.:||.:...||.....|:....:.|.:||.:     ..|.
Zfish   358 YYALILNTTNLHGNPYLNFFLSAVVEVPAYIIAALLLRFCSRRICQASTLLLGGAL-----IFII 417

  Fly   408 HLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIY 472
            .|.|||...|...:..||:...|.::.......:|:.||.||..|:.:..:.....|.::.::||
Zfish   418 QLIPTELQGLATALEMLGKLCVTAAFCVVYAVTSELFPTVVRNMAMGSCSMTARIGSIISPFIIY 482

  Fly   473 LAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLA 512
            |..||:.:|.|.|..|..|...:.|.|||:..|.||||:|
Zfish   483 LGNYYRYIPYIVIGGLALFSGVMSLLLPESKGKVLPETIA 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	151/547 (28%)
slc22a4	NP_957143.1	MFS_SLC22A4_5_OCTN1_2	106..510	CDD:340934	122/435 (28%)