DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and slc22a7b.1

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_021322800.1	Gene:	slc22a7b.1 / 393320	ZFINID:	ZDB-GENE-040426-1311	Length:	560	Species:	Danio rerio

Alignment Length:	566	Identity:	136/566 - (24%)
Similarity:	242/566 - (42%)	Gaps:	76/566 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65
            |.|..:||:...:||:|:.:::|.....|....|:.....|...|.|   |.|::.|..:|:.::
Zfish    11 MKFDNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAIPSH---HCDISSLDADGLGNL 72

  Fly    66 YE-------------------------------NISASSCTPLLGVVNGTGVVSTNRKCRNWIFN 99
            .:                               |.|:||..|::...||            |.|:
Zfish    73 TQKERLIVSVPAQEDGTPASCHMFAHPQFQLLINSSSSSALPVVECQNG------------WHFD 125

  Fly   100 RESGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGR----LPSLLMATLCGA 160
            ..:...::.|:...||||........:.||:|.:.|.:.||.|.|:.||    |.|.:.:.:...
Zfish   126 NSTFISTLATQFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSV 190

  Fly   161 TGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTS 225
            |..|.:|::    .||..||::||:...:..:..:|..|::..|.||| :.:..::.:..|.|..
Zfish   191 TSAFSSSYI----MFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTF-MGLFGSMSWSIGNMLL 250

  Fly   226 PWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEES 290
            ...|..:.:||..:.:.:.|........:.|.:||:||:...|.:.|...|.|.|.||:|.
Zfish   251 AGFAFMVTDWRLLIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNQRL---- 311

  Fly   291 VFDEFVKYYRERELQ-----DYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNM 350
               :|....:...|.     |::  .|..|:|.:..||:||:.||...:....:..:...|:.|:
Zfish   312 ---DFTSRVKPETLSTVVTVDHR--GHSYTYLDLVKTPQLRKLTLFTGIVWYGVASTYYGISLNI 371

  Fly   351 EGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENA 415
            .|.|..|:......:.:.:||.:.:....||:||:...     .|.|:.|....:|..:.|||..
Zfish   372 TGFGLDPYLTHFIYAAIEVPAKILVYFSLNKVGRRNTQ-----TGTLVLTGFCILINIITPTEYW 431

  Fly   416 LLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPL 480
            ....::..||:..:..|:...|.|..|:.||.:|...:...:.:....:|::..::.|...:|.|
Zfish   432 TFRTVIAVLGKGLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKLL 496

  Fly   481 PSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYF 526
            |.:....:..|...:.|.||||.|..||||:.|.|.  :.:..:||
Zfish   497 PEVIFCSMAIFCGIIALLLPETNNASLPETVEDIED--MRKKPVYF 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	126/538 (23%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	92/381 (24%)
slc22a7b.1	XP_021322800.1	Sugar_tr	22..526	CDD:331684	126/537 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950