Protein Alignment CG7333 and SLC22A10

DIOPT Version :9

• Sequence 1: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 146/570 - (25%)
• Similarity: 234/570 - (41%)
• Gaps: 94/570 - (16%)

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSL-----HYFSQTLITFTPEH--WCFHADLN-GL 57
            |.|.::|.:.|..||||::.|:.     ||.||     |...:......|.|  |....|.| |.
Human     1 MAFEELLSQVGGLGRFQMLHLVF-----ILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGS 60

  Fly    58 SVE-GIRS----------VYENISASSC----------TPLLGVVNGTGVVSTNRKCRNWIFNRE 101
            ..| ||.|          :..|:....|          ..|.|.::.|....|......|::::.
Human    61 GNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGWVYDQS 125

  Fly   102 SGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFIT 166
            ....:|.|:...|||.....:|.|.....|.:||.||.|::||:.||...|....|..|..|...
Human   126 YFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCLLQLAITDTCA 190

  Fly   167 SFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIW 231
            :|..|.|.:...||::|.|:..:.....:.:.|::.|.|:  .|.:||:.           .|:.
Human   191 AFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSK--ALVVILSS-----------GALS 242

  Fly   232 IG------------NWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNR 284
            ||            :|:....:||:|.....:....:.|||:||:...|.|:.:..|:|||:.|.
Human   243 IGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNG 307

  Fly   285 -RHVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRLR---------RFTLTLLVKSVII 339
             ::.||::..|.|:...:.||...:..:   |...:|..|.:|         ||..|:.....::
Human   308 IKNAEETLNIEVVRSTMQEELDAAQTKT---TVCDLFRNPSMRKRICILVFLRFANTIPFYGTMV 369

  Fly   340 TLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGF 404
                     |::.:|::.|.|......|.|......||..|.:||:......:|:.||...|..|
Human   370 ---------NLQHVGSNIFLLQVLYGAVALIVRCLALLTLNHMGRRISQILFMFLVGLSILANTF 425

  Fly   405 MIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHV----IGLASSS 465
            :     |.|...|...:..||...:..::.:...:..|:|||.:|.:| |.|.:    ||.|
Human   426 V-----PKEMQTLRVALACLGIGCSAATFSSVAVHFIELIPTVLRARA-SGIDLTASRIGAA--- 481

  Fly   466 LAFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGE 515
            ||..::.|..::..||.|........|..:...||||.|..||:|:.|.|
Human   482 LAPLLMTLTVFFTTLPWIIYGIFPIIGGLIVFLLPETKNLPLPDTIKDVE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	140/553 (25%)
		MFS	126..499	CDD:119392	98/398 (25%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	140/553 (25%)
		MFS	143..516	CDD:119392	100/406 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153699
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940