Protein Alignment CG7333 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_038941497.1
• Gene: Slc22a12 / 365398
• RGDID: 621628
• Length: 578
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 152/600 - (25%)
• Similarity: 249/600 - (41%)
• Gaps: 127/600 - (21%)

  Fly     1 MDFSQVLDKCGNYGRFQVM--ILLLYGYTNIL-----GSLHYFSQTLITFTPEHWCFHADLNGLS 58
            |.|.::||:.|..||||::  :.|:   |.||     ..|..||..:    |.|.|:
  Rat     1 MAFPELLDRVGGRGRFQLLQAVALV---TPILWVTTQNMLENFSAAV----PHHRCW-------- 50

  Fly    59 VEGIRSVYENISASSCTP-------LLGVVNGTG-----------------VVSTNRKCRN---- 95
                ..:.:|.::.:..|       ||.|....|                 ::.:|....|
  Rat    51 ----VPLLDNSTSQASIPGDFGRDVLLAVSIPPGPDQRPHQCLRFRQPQWQLIESNTTATNWSDA 111

  Fly    96 --------WIFNRESGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSL 152
                    |:::..:...:|.|....|||......:.||.|..|.:||..:.|:.||:.||...|
  Rat   112 DTEPCEDGWVYDHSTFRSTIVTTWDLVCDSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVL 176

  Fly   153 LMATLCGATGDFITSFVHTLPWFAFSRFM-----SGLSTDTMYYLMYILVF---EYLSPKSRTFG 209
            ..:.|..:....|.:.:.|.|.:...||:     :|:..:|....|:.:|.   .|:.....|
  Rat   177 TWSYLLVSVSGTIAALMPTFPLYCLFRFLVASAVAGVMMNTASLCMFPVVLGREGYMQDPELT-- 239

  Fly   210 LNIILAVF------------------YCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLI 256
            .:::|||.                  :.||.:.:...|..:.:||......|.|.....:|.:.:
  Rat   240 PSLLLAVMEWTSAQAGPLMMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWL 304

  Fly   257 CESAQWLLTKRKYDDAVICLKKVAKFNRRHVE-ESVFDEFVKYYRERELQDYKLNSHEDTFLAMF 320
            .|||:||:|..:.|.::..|::||..|||..| :::..|.::...:.|....:..:...|.|.
  Rat   305 PESARWLITVGRLDQSLRELQRVAAVNRRKAEADTLTVEVLRSAMQEEPNGNQAGARLGTLLH-- 367

  Fly   321 LTP--RLRRFTLTLLVKSVIIT---LSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQN 380
             ||  |||.|...|...:...|   |:.|     ::.||::.|.|.:...||.||..:..|||.:
  Rat   368 -TPGLRLRTFISMLCWFAFGFTFYGLALD-----LQALGSNIFLLQALIGIVDLPVKMGSLLLLS 426

  Fly   381 KIGRKGMACTALFVGGLITTATGFMIAHLDPTENALL---LAIMVGLGRFGATVSYDAEIQYAAE 442
            ::||:....::|.:.||...|.     .|.|.|..:|   ||:: |||..||  ::.....:::|
  Rat   427 RLGRRLCQASSLVLPGLCILAN-----ILVPREMGILRSSLAVL-GLGSLGA--AFTCVTIFSSE 483

  Fly   443 IIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFG-----AGL-CLTLPE 501
            :.||.:|..||....|.....:.|...|..|..|...||      |:.:|     :|| .|.|||
  Rat   484 LFPTVIRMTAVGLGQVAARGGAMLGPLVRLLGVYGSWLP------LLVYGVVPVLSGLAALLLPE 542

  Fly   502 TLNKKLPETLADGEK 516
            |.|..||:|:.|.:|
  Rat   543 TKNLPLPDTIQDIQK 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	145/582 (25%)
		MFS	126..499	CDD:119392	108/413 (26%)
Slc22a12	XP_038941497.1	MFS_OAT	109..541	CDD:340932	115/455 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346841
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950