DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and Balat

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	592	Identity:	153/592 - (25%)
Similarity:	251/592 - (42%)	Gaps:	86/592 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNIL------GSLHYFSQTLITFTPEHWCFHADLNGLSV 59
            |||.:||.:.|::|.:|.:|:     .::|      .:.|.:||..|..||:|:|...:|...:.
  Fly     1 MDFDEVLREVGSFGLYQKVII-----CSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQ 60

  Fly    60 EGIRSVYENISA--------SSCTPLLGVVNGTGVV------------------------STNR- 91
            :.::.| :|:|.        :.|:  :...|.|.:|                        .|.:
  Fly    61 DYVQLV-KNLSIPRNRNGAYAECS--MYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQV 122

  Fly    92 -KCRN-WIFNRESGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPS--- 151
             .|:: |.:::.....::..|...|||:|....:....|.:|.::|..:||||.|..||.||
  Fly   123 VPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYA 187

  Fly   152 -LLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILA 215
             ||:..:..|...|..::   ..|... ||:.||:...:....|:|..|.:.|:.|.| ..|:..
  Fly   188 YLLLEIIACAASAFAWNY---YTWLGL-RFVVGLTVPAILASPYVLAIELVGPERRVF-CTIVSN 247

  Fly   216 VFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVA 280
            :.|..||:........:.:||......|:|.|.:....|::.||.:||:...|...|:..||.:|
  Fly   248 IAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMA 312

  Fly   281 KFNRRHVEESVFDEFVK---YYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLV-----KSV 337
            :.|...|.....:...:   ..|..|.:. .:.:|.. .|.:|..|.:||.||.:.:     .||
  Fly   313 RVNGVRVNRDFVERLQRKLVITRAAETKS-SMTTHYG-ILDLFRGPNMRRKTLIITLIWFANTSV 375

  Fly   338 IITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTAT 402
            .:.||     .....||......|.....|.||..:.:....:..||:.:...::.|||:...||
  Fly   376 YVGLS-----YYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVAT 435

  Fly   403 GFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLA 467
                 .|.|....||..:    |:.|.:.|:......|:|:.||.|||..:|...||.:....:.
  Fly   436 -----FLYPDITLLLYCV----GKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVI 491

  Fly   468 FYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCF--S 530
            ..:.::.|....||.|.:..|:..|....|.||||.|:.||:||.:||...|  |||...|.  .
  Fly   492 PMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPL--SFLLCCCVESE 554

  Fly   531 RKEKNVR 537
            ||..|:|
  Fly   555 RKPNNIR 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	135/551 (25%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	99/384 (26%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	105/416 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458532
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	4.940