DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and Slc22a30

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_795976.1	Gene:	Slc22a30 / 319800	MGIID:	2442750	Length:	552	Species:	Mus musculus

Alignment Length:	568	Identity:	137/568 - (24%)
Similarity:	231/568 - (40%)	Gaps:	94/568 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVM----ILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEG 61
            |.|.::|::.|:.||||::    :|.|.|    |...|...:......|.|.|:
Mouse     1 MAFQELLNQVGSLGRFQILQISFVLFLVG----LVVPHITMENFTAAIPNHRCW----------- 50

  Fly    62 IRSVYENISASSCTPLLGVVNGTGVVSTN---------------RKCR----------------- 94
             ..:.:|.:||.        ||:.::|.:               .|||
Mouse    51 -APILDNDTASD--------NGSRILSQDDLLRISIPLDSNLRLDKCRRFAQPQWHLLHLNGTFS 106

  Fly    95 ------------NWIFNRESGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVG 147
                        .|:::|.:...:|.||...||:.....:|.:..|.:|..:|.||.|:|||:.|
Mouse   107 NETEPDTEPCVDGWVYDRSNFLSTIVTEWDLVCESQALNSVAKFSFMIGLFIGAIICGHLSDRFG 171

  Fly   148 RLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNI 212
            |...|..|.|..|..:...:|..:...:...||::|:|.:.:....::|:.|:.|||.    |.:
Mouse   172 RKFILTCALLQFAITETCVAFAPSFFIYCLLRFLAGMSVEPISVNSHLLMLEWTSPKF----LGM 232

  Fly   213 ILAVFYC---FGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVI 274
            :..:..|   .|.|.....|.....||......|:|....||....:.|||:||:...|....:.
Mouse   233 VAVLTSCAASIGYMILAGLAFLFRIWRHLQLAMSVPIFFFLILTRWMSESARWLIVTNKPQKGLK 297

  Fly   275 CLKKVAKFN-RRHVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVI 338
            .|:|||..| .::...::..|.|:...:.||:..|..|....   :|.||.||:....|.....:
Mouse   298 ELRKVAHMNGMKNSGNTLTMEVVEASMKNELEAAKRKSSPRD---LFHTPILRKRICVLSFMRYL 359

  Fly   339 ITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATG 403
            .|:|...::.:::.|.|:...|...:|.:.:...|....:.|.:||:......:.:.|:......
Mouse   360 FTISIFGLSLHLQHLSTNIILLQFLSSALGILISVIGHFVLNHMGRRITQLVLMSLRGIFMLTAV 424

  Fly   404 FMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAF 468
            |:     |.|...|..||..|....:::.......:..|::||::|...:..|.:.|.:...||.
Mouse   425 FV-----PQEMQTLRIIMATLAAALSSLCMCVSNLHINELLPTTLRATGMGVIAMFGNSGLFLAP 484

  Fly   469 YVIYLAQYYKPLPSIF---ISCLMFFGAGLCLTLPETLNKKLPETLAD 513
            ..:.||.|...||.||   .|.|..|...|   ||||.|:.||:::.|
Mouse   485 LFMLLATYSANLPWIFYGGFSILYGFSVFL---LPETKNQPLPDSIHD 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	133/553 (24%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	96/379 (25%)
Slc22a30	NP_795976.1	2A0119	11..525	CDD:273328	132/552 (24%)
Slc22a30	NP_795976.1	MFS	151..516	CDD:119392	96/379 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843957
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940