DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001381833.1	Gene:	Slc22a20 / 293686	RGDID:	1311460	Length:	556	Species:	Rattus norvegicus

Alignment Length:	541	Identity:	138/541 - (25%)
Similarity:	232/541 - (42%)	Gaps:	50/541 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNIL----GSL--HYFSQTLITFTPEHWCFH------AD 53
            |.|:.:||..|..||||::      ||.:|    |.|  |.|.|......|.|.|.|      |.
  Rat     1 MAFTDLLDALGGVGRFQLV------YTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEAT 59

  Fly    54 LNG----------LSVEGIRSVYENISASSCTPLLGVVNGTGVVSTNRKCRN-WIFNRESGYESI 107
            .|.          |:..|:....:..:......|....:..||.:..  |:: |:::|.....:|
  Rat    60 TNDSGAWLRATIPLNQHGVPEPCQRYTEPQWALLEPNTSSHGVATEG--CKDGWVYDRSIFPSTI 122

  Fly   108 TTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTL 172
            ..|...||:......:.||.:..|.:||..:||.|:|::||...|:.:.|..|....:|::|.:.
  Rat   123 VMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGSLADRLGRKAPLVWSYLQLAVSGAVTAYVGSF 187

  Fly   173 PWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRR 237
            ..:...||:.|::...:......||.|::..:.||.. .|:|...:..|.:.....|..|..||.
  Rat   188 SAYCIFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVA-GILLGFSFTLGQLILAGVAYLIRPWRW 251

  Fly   238 YLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVE-ESVFDEFVKYYRE 301
            ..:..|.|.|...:|.:.:.||::|||...|...||..|:|||..|.|..| |.:..|.|..|.:
  Rat   252 LQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKVAMMNGRKAEGERLTIEVVSSYIQ 316

  Fly   302 RELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSI 366
            .|....:.:   ::.|.:|.||.:|:.|..|::.....:::...:..:::..|.|.:.:.:...|
  Rat   317 NEFASVRTS---NSILDLFRTPGIRKVTCCLMMVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGI 378

  Fly   367 VYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATV 431
            :.:||.:........:||:....:.|.:.||:..|..|:     |.:...|..:...||:.....
  Rat   379 IDIPAMLVATTTMIYVGRRATVSSFLVLAGLMVIANMFV-----PEDLQTLRTVQAALGKGCLAS 438

  Fly   432 SYDAEIQYAAEIIPTSVR----GQAVSNIHVIGLASSSLAFYVIYLAQYYKPLPSI-FISCLMFF 491
            |:.....:..|:.||.:|    |.|..|..:.|||    |..:..|.:....||.: |.:..:..
  Rat   439 SFICVYLFTGELYPTEIRQMGMGFASVNARLGGLA----APLITTLGEISPVLPPVSFGATSVLA 499

  Fly   492 GAGLCLTLPETLNKKLPETLA 512
            |..:...|.||.|..|.||:|
  Rat   500 GMAVICFLTETRNVPLVETIA 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	131/527 (25%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	94/378 (25%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	102/419 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347033
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940