DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and Slc22a19

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_659034.1	Gene:	Slc22a19 / 207151	MGIID:	2442751	Length:	551	Species:	Mus musculus

Alignment Length:	542	Identity:	134/542 - (24%)
Similarity:	237/542 - (43%)	Gaps:	38/542 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCF-------HADLNG-- 56
            |.|..::.:.|:.||||::.::.....:.|.:.|...:......|.|.|:       .|..||
Mouse     1 MAFQDLIIQIGSLGRFQILHMIFVLICHALSAPHTLLENFTAAIPSHRCWVPILDNDTASDNGSR 65

  Fly    57 -LSVEGIRSVY----ENISASSCTPLLGV------VNGTGVVST---NRKC-RNWIFNRESGYES 106
             ||.:.:..:.    .|:....|...:..      :|||....|   ...| ..|::::.:...:
Mouse    66 ILSQDDLLRISIPLDSNLRPDKCRRYIQPQWHLLHLNGTFPTVTEPDTEPCVDGWVYDQSTFLST 130

  Fly   107 ITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHT 171
            ..|:...||......:|.:..:..|..:|.|:.|:|||:.||......:.|..|..:...:|..:
Mouse   131 TVTQWDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDKFGRKLIFTCSLLKMAITETCVAFAPS 195

  Fly   172 LPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTS--PWAAIWIGN 234
            ...:...||:||:.:.|:.....:|:.|:.|||   |...::..:|...|:..:  ...|....|
Mouse   196 FLIYCSLRFLSGIFSSTLRTNSALLILEWTSPK---FQALVMALIFIASGVGQTLLGGLAFAFRN 257

  Fly   235 WRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNR-RHVEESVFDEFVKY 298
            |.......|:|...:||....:.|||:||:...|...::..|||.|..|| ::..:::..|.||.
Mouse   258 WHHLQLALSVPMFLLLIPTRWLSESARWLIMANKPQKSLKELKKAACVNRIKNSGDALTLEVVKT 322

  Fly   299 YRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSF 363
            ..:.||:..:.   :.:.|.:|.||.||:....|.....:..:|...:..|::.|..:.|.|...
Mouse   323 IMKEELEAAQT---KPSPLDLFRTPNLRKRICLLSFVRFVSVMSLLGLLINIQYLSNNVFLLQCL 384

  Fly   364 TSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFG 428
            ..:|.:||.|......|.:||:......:.|.|:...|..|:     |.|..:|...:..||...
Mouse   385 YGVVCIPANVLGNFSMNYMGRRMTQLIFMSVLGISILAVVFL-----PQEMQILRVFLSTLGGAI 444

  Fly   429 ATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGA 493
            ::.|..:.:.:|.|::||.:|..|:..:.:.|.|..:|:..::.|..|...||.|....|.|.|.
Mouse   445 SSASITSTLVHANELVPTIIRATALGVVGIAGSAGGALSPLLMILTTYSASLPWIIYGILPFLGG 509

  Fly   494 GLCLTLPETLNKKLPETLADGE 515
            .:.|.||||.|:.||:::.|.|
Mouse   510 LVALLLPETKNQPLPDSIQDIE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	130/525 (25%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	96/375 (26%)
Slc22a19	NP_659034.1	Sugar_tr	11..525	CDD:331684	129/524 (25%)
Slc22a19	NP_659034.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..551		3/8 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940