Protein Alignment CG7333 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 581
• Identity: 152/581 - (26%)
• Similarity: 239/581 - (41%)
• Gaps: 94/581 - (16%)

  Fly     6 VLDKCGNYGRFQ-----VMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLS------- 58
            :|:..|.:..||     ::.||...:|.|     |.....:.|||.|.|....:..||
Mouse     7 ILEHIGEFHLFQKQTFFLLALLSGAFTPI-----YVGIVFLGFTPNHHCRSPGVAELSQRCGWSP 66

  Fly    59 -------VEGIRSVYENISASSC--------TPLLGVVNGTGVVSTNRK------CRN-WIFNRE 101
                   |.|:.|..|....|.|        ...|..|:....::.||.      |.: |:::..
Mouse    67 AEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWVYDTP 131

  Fly   102 SGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFIT 166
            .  .||.||...||..|....:.||...:|..:|.:..|||:|:.||...||:..|..|....:.
Mouse   132 G--SSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLM 194

  Fly   167 SFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLS-PKSRTFGLNIILAVFYCFGLMTSPWAAI 230
            :......|....||:.||.:...:.:.|||:.|::. ...||.|  |...:.:..||:.....|.
Mouse   195 AISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTVG--ICYQIAFTVGLLILAGVAY 257

  Fly   231 WIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEF 295
            .:.|||...:..:||....|:|.:.|.||.:||:::.|...|:..:|.:||.|.:.|..|:
Mouse   258 ALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVSL---- 318

  Fly   296 VKYYRERELQDYKLNSHEDT-------FLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGL 353
                       ..|.:.|||       ||.:..||::|:.||.|:......::....:..:|...
Mouse   319 -----------QSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLA 372

  Fly   354 GTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLL 418
            |.:.:..|.::::|..||...|:|..::|||:.....:..|.|....|:.|:     |.:...|.
Mouse   373 GDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFI-----PDDLQWLK 432

  Fly   419 AIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLA--------FYVIYLAQ 475
            ..:..|||.|.|::|:......||:.||.:|..||       |..||:.        |.|..|..
Mouse   433 ITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAV-------LVCSSMCDIGGIVTPFLVYRLTD 490

  Fly   476 YYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCFSRKEKNV 536
            .:...|.:..:.:.....||.|.||||..|.||||:.|.||.....        .:|||.:
Mouse   491 IWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQRPR--------KKKEKRI 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	143/548 (26%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	143/548 (26%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		2/3 (67%)