DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and suex-2

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_501556.2	Gene:	suex-2 / 183742	WormBaseID:	WBGene00008271	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	561	Identity:	127/561 - (22%)
Similarity:	194/561 - (34%)	Gaps:	194/561 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RFQVMILLLYGYTNILGSLHYFSQTLI----------TF-TPEHWCFHADLNGLSVEGIRSVYEN 68
            |..:.:::||..|.|      ||..||          |: |.:::|:......|      ..|::
Worm     6 RLDITVMVLYQITLI------FSAQLIFVIFLDFMPSTYCTDDNFCYKLQSKCL------MDYDH 58

  Fly    69 ISASSCTPLLGVVNGTGVVSTNRKC---RNWIFNRESGYE-----------SITTELKWVCDKSH 119
            .:.:.|.     ||.|...|   ||   .:.:|.|.:.:|           |::|..
Worm    59 NAQNLCP-----VNMTENAS---KCIADHSRLFFRSAQFEYQQDCTGLNGFSLSTAT-------- 107

  Fly   120 HPAVGQSFFFMGSVVGTIIFGYLSDQVGR----LPSLLMATLCGATGDFITSFVHTLPWFAFSRF 180
                     |:|:::|.|..|:|:|:.||    |.|||....|......||:...    |...|.
Worm   108 ---------FIGTLLGNIALGFLADKYGRRTIYLSSLLFGIPCVVLSAAITNIYS----FYIFRI 159

  Fly   181 MSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPW---AAIWIG------NWR 236
            :.|:|......:.:....|.:||..|   |.|         |..|.|   ..|.:|      .|:
Worm   160 LIGISVSGTLTVGWTYATEMISPNRR---LRI---------LAFSNWPNARMIQVGLAYISQEWK 212

  Fly   237 RYLWL---ASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKY 298
            ...::   .|..:|.:|||   :.||..||..|:||.:|....|::.|..             |:
Worm   213 TATYICAAVSCLSLPILIY---LPESPIWLDQKQKYKNASKARKRLRKIG-------------KF 261

  Fly   299 YRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSF 363
            |.         |.| .|.:|.      |:||.|.::|        |...||            ||
Worm   262 YS---------NEH-STVVAN------RKFTPTRILK--------DPKLRN------------SF 290

  Fly   364 TSIV--YLPAGVAILLLQ-NKIGRKGMACTALFVGGLITTATGFMIAHLDPTENAL------LLA 419
            ..|:  |...|:|:.:.. |............|:.||:.:...|:|...:|....|      |:|
Worm   291 FMIIFMYFYVGLAVYITDLNGADMTKNLYLGQFLSGLVLSIAQFIIGMTEPYLTGLGRRVLFLIA 355

  Fly   420 IMVGL---------------GRF---------GATVSYDAEIQYAA--EIIPTSVRGQAVSNIHV 458
            ..:.:               |.|         .||.|...|..|.:  |::||.||..|.|..::
Worm   356 QFIAMLCYICILICLYLNWKGSFLYLSAYTLAYATQSLCLEAAYLSLVELMPTDVRATAGSTANI 420

  Fly   459 ---IGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGLC 496
               ||          ..||...|||...:...|.|....:|
Worm   421 CMKIG----------TILATLTKPLKFAYEPSLFFINLSIC 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	127/561 (23%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	101/425 (24%)
suex-2	NP_501556.2	MFS	108..460	CDD:391944	101/422 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910