DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7333 and C06H5.6

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_507509.3	Gene:	C06H5.6 / 180170	WormBaseID:	WBGene00007394	Length:	556	Species:	Caenorhabditis elegans

Alignment Length:	580	Identity:	136/580 - (23%)
Similarity:	243/580 - (41%)	Gaps:	115/580 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSV 65
            :|..:||...|.|||:|::..::....::|.:|:......||.:.|..|...|
Worm    25 LDADKVLTAFGKYGRYQMLAYVITTSVHMLFALNMMIMPFITKSVEFLCDLPD------------ 77

  Fly    66 YENISASSCTPLLG-----------------VVNGTGVVSTNRKCRNWIFNRESGYESITTELKW 113
            .|:|.::..:||:|                 .|||...        |::.:::|   :||::...
Worm    78 PESIDSAHFSPLVGDSCHLQDTQLNITIDCLAVNGASY--------NYLADKKS---TITSDFDL 131

  Fly   114 VCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFS 178
            ||:.........|.|.:|.::.:.....|||.:||.|..|:........:.|.:.......|...
Worm   132 VCEYQGMAEHATSIFLVGGMIVSPFVSQLSDILGRRPLFLIPLYISVAANLICAAAPNYLIFLLF 196

  Fly   179 RFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLAS 243
            ||:||::|.:.....::|..|.:|.:.|:. :.::..:.:..|.|.:....::..|||...:.||
Worm   197 RFISGVATTSFSMTGFVLCMESVSLEFRSL-IPVLTTISWVGGYMLAGVFYVFFKNWRVLYFAAS 260

  Fly   244 LPALGVLIYPF--LICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESV-FD-EFVKYYREREL 304
            :|  |:|..||  ...||..||:||:  :|     :|:.|:    :.||| |: :.:.....|.:
Worm   261 VP--GLLTIPFFWFTPESLHWLMTKQ--ND-----RKIKKY----INESVAFNKQTISLIDCRNI 312

  Fly   305 Q---DYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTS-PFKLFS--- 362
            |   :....:...||.|:|. |::  |...::...::|.:|           ||. ...|:|
Worm   313 QTVDNAPATTKTRTFRALFY-PKI--FVHVVINSFILIVMS-----------GTYWALSLYSTEL 363

  Fly   363 ---------FTSIVYLPAGVAILLLQNKIGRK-----GMACTALFVGGLITTATGFMIAHLDPTE 413
                     .:.:|.||||...:.|.....||     .:|.||:|:  |.|       .::....
Worm   364 SEDETTGYFLSGLVELPAGFLSVFLLIAFKRKTVSFYSLAFTAVFM--LCT-------VYIPMQG 419

  Fly   414 NALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYK 478
            |..::..:  |.:...::.:.::....:|..||::|......:..:|...|..|.|:..|....:
Worm   420 NYKMIFPL--LAKSTNSIVWASQPLLYSEATPTTIRNVFSGVVSFVGELGSIGAPYMNRLTAINQ 482

  Fly   479 PLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCFS--RKEKNV 536
            ..|:|.||.:....|.|.|..|||.||||||.|         :.|...|.|.  :|:|::
Worm   483 DAPAILISIMSIVAAFLVLLQPETKNKKLPEDL---------DQFDAGPLFRGWKKQKDL 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	126/540 (23%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	92/397 (23%)
C06H5.6	NP_507509.3	MFS_SLC22	115..504	CDD:340875	98/438 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010