DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and Y82E9BR.16

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001022960.1	Gene:	Y82E9BR.16 / 175300	WormBaseID:	WBGene00022348	Length:	575	Species:	Caenorhabditis elegans

Alignment Length:	584	Identity:	133/584 - (22%)
Similarity:	231/584 - (39%)	Gaps:	119/584 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GNYGRFQVMILLLYGYTNILGSLHYFS-------------------------QTLITFTPEHWCF 50
            |..|::|.:...|.....|:.|:|..|                         .||:.||.   |.
Worm    12 GEMGKYQKIQFFLVCLPTIVVSMHALSWTFASVDTPYRCRLPSDLPEKEPYYTTLLNFTK---CT 73

  Fly    51 H-ADLNGLSVE----GIRSVYENISASSCTPLLGVVNGTGVVSTNRKCRNWIFNRESGYESITTE 110
            : ||.|....|    |:...|:.     ||           :..|..|...||:...  ...|..
Worm    74 NDADANVPISEYGKPGVTCHYDR-----CT-----------LPDNETCHEHIFDHSK--VEYTAV 120

  Fly   111 LKW--VCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLP 173
            .:|  .||:|...|..|:.:::|.:.|:..||.|.|::||.....:|.:...|..::.:......
Worm   121 QRWEITCDRSWIKATIQAAYYVGQMAGSTTFGMLGDRIGRKKVFFLAIVIQITCAYLIAIAPYWW 185

  Fly   174 WFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRY 238
            .:|.:|..:|.|...::.:..::..|.:.||.|... ::|..:|:..|.:.....||:..|::..
Worm   186 LYALARAGTGFSHPGIFVIAVVIGMELVGPKYRKLA-SVITGLFFALGQIFLGIEAIYFTNYQIL 249

  Fly   239 LWLASLPALGVLIY-----------------------------PFLICESAQWLLTKRKYDDAVI 274
            ..:.:.|||..|.|                             .:|:.|||:||:::::|.:|..
Worm   250 HVVIASPALLFLSYCQKSAKNRKKIDFANFLADFLLKNRFFFSRWLVPESARWLVSQKRYKEADE 314

  Fly   275 CLKKVAKFNRRHVEESVFDEFVKYYRERELQD-------------YKLNSHEDTFLAMFLTPRLR 326
            .|:|.|..|...:.|:.::         :|.|             .||...:     :|.||.||
Worm   315 VLQKAASVNGTVLPENWWE---------QLDDSTTGGGGAPGAPTKKLTGAD-----LFRTPELR 365

  Fly   327 RFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTA 391
            :.||.:.....:|::....:......||...:..|.|.:.|.:||...:.||.::|||:     .
Worm   366 KRTLVVFFLWPVISMVYYGMAMKANVLGGDIYVNFIFAAFVEIPALFIVYLLIDRIGRR-----L 425

  Fly   392 LFVGGLITTATGFMIAHLDPTENALLLAI-MVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSN 455
            :..|||.......::..|......|.:|| .:...:...|..|.|...|:.|:.||.:|..|:..
Worm   426 ILAGGLFIAGACLLVNWLMGDNVQLWMAITQMAFTKGSITGVYAAIYTYSPELFPTVIRNTAMGF 490

  Fly   456 IHVIGLASSSLAFYV-IYLA-QYYKPLPSIFISCLMFFGAGLCLT-LPETLNKKLPETLADGEK 516
            ...|....:..|.|: :::| |:.|....|...|:....|.:.|. ||||:.|.|||::.:.|:
Worm   491 CSTIARVGAIAASYISMWIAEQFGKVFMIIPFGCMAVLAAVMTLLFLPETMGKPLPESIEEIEE 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	131/576 (23%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	92/418 (22%)
Y82E9BR.16	NP_001022960.1	MFS_SLC22	107..537	CDD:340875	101/451 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010