Protein Alignment CG7333 and SLC22A9

DIOPT Version :9

• Sequence 1: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 126/593 - (21%)
• Similarity: 228/593 - (38%)
• Gaps: 110/593 - (18%)

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCF-HADLNGLSVEGIRS 64
            |.|..:|...|:..|||::..:......:...||:..:....|.|.|.|: |
Human     1 MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVH------------- 52

  Fly    65 VYENISASSCTPLLGVVNGTGVVSTN---------------RKCR-------------------- 94
            :.:|.:.|.        |.||.:|.:               .|||
Human    53 ILDNDTVSD--------NDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTS 109

  Fly    95 ---------NWIFNRESGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLP 150
                     .|:::|.|...:|.||...|||.....:|.:..|..|.:||.|:.|:|||:.||..
Human   110 DADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRF 174

  Fly   151 SL----LMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLN 211
            .|    |...:.|.......:|:    .:...||:||::..::.....:|:.|:.:.:.:..|:.
Human   175 VLRWCYLQVAIVGTCAALAPTFL----IYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGIT 235

  Fly   212 IILAVFYC---FGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAV 273
            :.:    |   ...||....|..|.:|.....:.|:|...:.:....:.|||:||:...|.::.:
Human   236 LGM----CPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGL 296

  Fly   274 ICLKKVA-KFNRRHVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRL-RRFTLTLLVKS 336
            ..|:|.| :...::..:::..|.:|...::||:  .....:.:...|...|.: :|.:|....:.
Human   297 KELRKAAHRSGMKNARDTLTLEILKSTMKKELE--AAQKKKPSLCEMLHMPNICKRISLLSFTRF 359

  Fly   337 VIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTA 401
            ... ::...:|.:::.||.:.|.|.:....|.|.|..........:.|:......:|:..:...|
Human   360 ANF-MAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAICLLA 423

  Fly   402 TGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSL 466
            ..|:     |.|...|..::..||...:.::......:..|:|||.:|.:|:.........:.:|
Human   424 IIFV-----PQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGAL 483

  Fly   467 AFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCFSR 531
            |..::.|:.|..|||.|......|......|.||||.||.|.:|:.|
Human   484 APLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD------------------ 530

  Fly   532 KEKNVRTE 539
             |||.|.:
Human   531 -EKNERKD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	117/552 (21%)
		MFS	126..499	CDD:119392	80/381 (21%)
SLC22A9	NP_543142.2	Sugar_tr	11..527	CDD:331684	117/552 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		5/29 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153770
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940