DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and slc22a16

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_002936981.2	Gene:	slc22a16 / 100488673	XenbaseID:	XB-GENE-961385	Length:	567	Species:	Xenopus tropicalis

Alignment Length:	593	Identity:	137/593 - (23%)
Similarity:	244/593 - (41%)	Gaps:	94/593 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHAD------LNGLSVEGIR 63
            ::.|..|::||||.:|.....:..|...:||.:...|..||:..|...:      |...|...:.
Frog     3 RLFDYVGHFGRFQALIYFSSAFQAISCGIHYLASVFIAITPKFICRAPENISSVLLPNASTLRLE 67

  Fly    64 SVYENISASSCTP--LLGVVNGTGVVSTNRKCRNW-----------------IFNRESGY----- 104
            .|:|     ..||  .|.|....|.:....:|..:                 :|:..:||
Frog    68 DVWE-----LWTPKDYLVVKQENGDIWELNQCSRFKRENTSYLTYSYDGNKTLFSCSNGYYYDNT 127

  Fly   105 ---ESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFI- 165
               .||.|:...||::.....:.|..|..|.::|.:|||.::|:|||...|.:.    :||.|:
Frog   128 NLESSIVTDWHLVCEREWLAKLIQPTFMFGVLIGAVIFGDIADRVGRRLILWLT----STGQFLF 188

  Fly   166 -TSFVHTLPWFAF--SRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPW 227
             .:...|..:::|  .||:..:.:...|.::::.|.||:..|:|::. ::.:..|:..|:|....
Frog   189 GIAVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYVTEYVGIKARSWA-SMHVHAFFAVGVMIVSL 252

  Fly   228 AAIWIGNWRRYLWLASLPALGVLIYPFLIC-----ESAQWLLTKRKYDDAVICLKKVAKFNR--- 284
            ....:..|..|..:.||..|     ||::|     |:..||.::.|:.:....:..:.|:|:
Frog   253 VGFLVRTWWMYQIILSLTTL-----PFVLCCWMLPETPFWLYSQGKHKEVEKLIGTIEKWNKIST 312

  Fly   285 -------RHVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLS 342
                   ..|:|:         ::.|:...|.:|    .|.:|......|.|:|:.:.....:|.
Frog   313 PCKLSELCSVQET---------QKTEMDTLKKHS----VLDLFYNWSFARRTVTVWLIWFTGSLG 364

  Fly   343 CDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIA 407
            ..|...|...||.:.:.....||.|.:|:.:......:||||:......|.:..:|..     |.
Frog   365 YYVFALNSVNLGGNEYLNLFLTSAVEIPSYIVACFGMDKIGRRNTLAPFLILSAVICG-----II 424

  Fly   408 HLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIY 472
            .|.|.:::.:...|...|:|...|::.....|.||:.||.||..||.:..::....|.:|.:.:|
Frog   425 MLIPQDHSTVTIAMSMGGKFSIAVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVY 489

  Fly   473 LAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCFSRKE---- 533
            |...:..:|.:.:..:.|....|.|.|||||...|..|:.:..:...|....     .||.
Frog   490 LTDVWIFMPQMLVGIMAFLTGVLTLKLPETLGVPLTSTIEEAAEMGTNNRIT-----KRKSITEC 549

  Fly   534 KNVRTESV 541
            |.|..|:|
Frog   550 KGVLMENV 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	128/550 (23%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	90/391 (23%)
slc22a16	XP_002936981.2	MFS_SLC22A16_CT2	111..517	CDD:340933	99/433 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000