DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and slc22a13a

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_021322911.1	Gene:	slc22a13a / 100007819	ZFINID:	ZDB-GENE-070912-473	Length:	537	Species:	Danio rerio

Alignment Length:	554	Identity:	132/554 - (23%)
Similarity:	233/554 - (42%)	Gaps:	82/554 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLI---TFTPEH----WCFHADLNGLSV 59
            :|.::|:..|::|.||.::|....:.|::  |.:...:|:   ..|..|    |...||.|....
Zfish     3 NFGEILEAIGDFGLFQKLLLFALCFPNLI--LPFQLSSLVFNHADTNHHCNTDWILKADPNLTKE 65

  Fly    60 EGIRSVYENISASSCTPL---------LGVVNGTGVVSTNRKCRNWIFNRESGYE-SITTELKWV 114
            |.:......:|..|..|.         |..:...|:..|......|:.| ::.|| :|.|:...|
Zfish    66 EQLNLTLPRLSDGSFNPCQMYKPVDWNLSAIQEYGLNQTTTCTDGWVHN-DTIYEATIVTDFDLV 129

  Fly   115 CDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGR-----LPSLLMATLCGATGDFITSFVHTLPW 174
            |:..:.....|:.||.|.:||.|:||..|:..||     :|.:||......||.....:|:.:
Zfish   130 CENVNIFRGAQTVFFAGVLVGAILFGPFSESFGRKRATQIPMVLMLIFTVVTGLSPNFYVYLV-- 192

  Fly   175 FAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTF-----------GLNIILAVFYCFGLMTSPWA 228
               |:|::|:..........||..|::....|::           |..:.|||.|
Zfish   193 ---SQFINGVGLGGFRINSIILASEWIGVAQRSYAACLSQVLAALGQVMFLAVVY---------- 244

  Fly   229 AIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFD 293
              ::.:||...::.:.|...|:||.:.:.|||:|||.:.:..||...::|.|..|:|.|.||:.:
Zfish   245 --FVRDWRLDQFIMAGPIGIVVIYIWFLPESARWLLDRGRTKDAKKLIQKAAAVNKRAVPESLVE 307

  Fly   294 EFVKYYRERELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPF 358
            |.:|   |:.::       :.....:|.:..||::.|.:......:.|:...::.|:...|...|
Zfish   308 EVLK---EKPVE-------KGGIKILFGSRVLRKYFLAITFAWCALNLAYYSLSLNVGKFGLDIF 362

  Fly   359 KLFSFTSIVY----LPAGVAILLLQNKIGRKGMACTALFVGG---LITTATGFMIAHLDPTENAL 416
                .|.:::    :|.....:.....:|||.....:|.:||   |:|.|.        |..:::
Zfish   363 ----LTQLIFGLSEIPVHFLCMWSLEVVGRKPSLIVSLVLGGCLCLLTVAV--------PQNSSI 415

  Fly   417 LLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPLP 481
            .:|::...|||....:......|..|:.|||:|..|.........|.|.|:..|..|..::..:|
Zfish   416 AIAVLATCGRFLMNAAGSVCNVYFQELFPTSIRQTATGLGSTAARAGSMLSPVVNMLEIFHFSIP 480

  Fly   482 SIFISCLMFFGAGLCLTLPETLNKKLPETLADGE 515
            .:.||.|..........||||...:||.:..:.|
Zfish   481 MVVISSLALASGVTAFLLPETRRTELPASTEEAE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	129/538 (24%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	93/395 (24%)
slc22a13a	XP_021322911.1	Sugar_tr	12..507	CDD:331684	127/536 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588894
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950