DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7333 and si:dkey-166k12.1

DIOPT Version :9

Sequence 1:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_001341287.1	Gene:	si:dkey-166k12.1 / 100001249	ZFINID:	ZDB-GENE-120215-78	Length:	537	Species:	Danio rerio

Alignment Length:	544	Identity:	135/544 - (24%)
Similarity:	230/544 - (42%)	Gaps:	62/544 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEH-----------WCFHADL 54
            |:|.|:|...|.:|::|.::.:......|....|..:......||.|           |.|.::|
Zfish     1 MNFDQLLATIGGFGKYQKLLYVWICLPQIFLGFHMMASVFTGATPPHRCRGSTSGMEDWTFTSNL 65

  Fly    55 N--GLSVEGIRSVYENISASSCTPLLGVVNGTGVVSTNRKCR-----NWIFNRESGYESITTELK 112
            :  .||:..:...     |.:||...||         ||..|     .|:::.|....:..||..
Zfish    66 SHVNLSISRLAGF-----ADACTAASGV---------NRSARTNCETGWVYSHEVFQSTTVTEWD 116

  Fly   113 WVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGR----LPSLLMATLCGATGDFITSFVHTLP 173
            .||||....::|.|.:.:|.:||.::||.::|:.||    |.||.:.|:.|....|..:|    |
Zfish   117 LVCDKRGLSSLGSSIYMLGLLVGAVVFGAMADRYGRRFAMLVSLALQTVFGVAAAFAPNF----P 177

  Fly   174 WFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRY 238
            .:...||:.|::...:....::|..|:...:.|... .|....|:.||.|.....|..|.:||:.
Zfish   178 VYVGLRFIIGMTVSGVIINAFVLGTEWTCTQRRMLA-GIFTDYFFGFGYMLLAGVAFLIRDWRKL 241

  Fly   239 LWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERE 303
            ....|.|....:.|.:::..||:|||...:.::|:..|:|.|..|.|.:..:|  :..:|...:.
Zfish   242 QLAISAPGFLFIFYIWVLPHSARWLLVNNRKEEAIDLLRKAASVNGRTLPPTV--QVERYESPQG 304

  Fly   304 LQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVY 368
            ...|       |.:.:..||::|:..|.|.....:..|....::..:..||...:.......:|.
Zfish   305 RSKY-------TVVDLLRTPQMRKRALILFYIWFVNVLVYYGLSLGVSDLGADLYLTQFMFGLVE 362

  Fly   369 LPAGVAILLLQNKIGRKGMACTALFVGG---LITTATGFMIAHLDPTENALLLAIMVGLGRFGAT 430
            :||...:|:|. ...||......|.|||   |:|...        |.::|.:...:..:|:||.|
Zfish   363 IPARTLVLVLL-PCSRKIPLSVFLVVGGGACLLTLTL--------PADSAHVRTALAMVGKFGIT 418

  Fly   431 VSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGL 495
            .|:.....|:||:.||.:|...:....:.......||..:..|.::...:|.:.........|.|
Zfish   419 ASFAIIYVYSAELFPTVLRQTGIGVSSMFARMGGVLAPLINLLGRHTPVVPMLIFGSTPLLAAAL 483

  Fly   496 CLTLPETLNKKLPETLADGEKFAL 519
            .|.||||..:.||:::.|.||..|
Zfish   484 ALALPETARQPLPDSIHDTEKSTL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	127/523 (24%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	91/379 (24%)
si:dkey-166k12.1	XP_001341287.1	2A0119	11..497	CDD:273328	126/522 (24%)
si:dkey-166k12.1	XP_001341287.1	MFS	123..458	CDD:119392	87/357 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950