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Protein Alignment Dys and dah

DIOPT Version :9

Sequence 1:	NP_001036722.1	Gene:	Dys / 42327	FlyBaseID:	FBgn0260003	Length:	3598	Species:	Drosophila melanogaster
Sequence 2:	NP_511162.1	Gene:	dah / 32459	FlyBaseID:	FBgn0015926	Length:	649	Species:	Drosophila melanogaster

Alignment Length:	750	Identity:	157/750 - (20%)
Similarity:	243/750 - (32%)	Gaps:	212/750 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  2881 EMIELMKGL-ADLNEIRFSAYRTAMKLRSVQKRLALDRISMSTACESFDRHGLRAQNDKLIDIPD 2944
            |:..:|..| .|....:::.||.|.|..::||.....:|.........|||.|....:.::....
  Fly    42 ELSTIMDDLQRDYGNYKYTVYRCASKFVALQKIFHTGKIPYKLVLAILDRHNLSGGLELMVPPFQ 106

  Fly  2945 MTTVLHSLYVTIDKI-----DLTLMLD----LAINWILNVYDSQRTGQIRVLSFKVGLVLLCK-- 2998
            :|::||.:|...:|:     |....||    |..|:..||||.||...|.:|..::..:||||
  Fly   107 LTSLLHDVYFACEKLGHFNQDANYKLDRATGLLANFFWNVYDPQRRHSISLLEIRITFILLCKLY 171

  Fly  2999 --GHLEEKYRYLFRLVADTDRRADQR-RLGLLLHDCIQVPRQLGEVAAFGGSNIEPSVRSCLEQA 3060
              .||...   :|.|:||...:...| ....||....::...|||..|:|..|:..::..|..:.
  Fly   172 SSDHLVGD---IFGLLADPKSQIISRYAFEQLLATLSKLLSYLGEAKAYGVHNLPLAMEQCFARC 233

  Fly  3061 GISQEAIDGNQDISIELQHFLGWLQHEPQ-SLVW---------------LPVLHRLAAAEAAKHQ 3109
                             .|.:|.|. ||| ..:|               |.::.|:...|...|.
  Fly   234 -----------------PHGVGGLT-EPQFHKLWTGAGVQTRFLIYGNLLALVKRIEDTEHLIHS 280

  Fly  3110 AKCNICKEYPIVGFRYRCLKCFNFDMCQKCFFFGRNAKNHKLTHPMHEYCTTTTSTEDVRDFTRA 3174
            ..|..|::..|||.|:||..|.:..:|..||..|.....|:   |.|..|......:....:||.
  Fly   281 NSCAGCRKEHIVGIRFRCQVCRDISLCLPCFAVGFAGGRHE---PGHRMCEVFVEDQPPLRWTRH 342

  Fly  3175 LKN----KFKSRKYFKKHPRVGYLPVQSVLEGDALESPAPSPQHTTHQLQNDMHSRLEMYASRLA 3235
            |..    ....|| .::..|.|:...|.  .|.||...|.:|
  Fly   343 LARLCGWLVMPRK-TQEEERRGFCNAQE--SGPALGQSAATP----------------------- 381

  Fly  3236 QVEYGGTGSNSTPDSDDEHQLIAQYCQALPGTSNGSAPKSPVQVMAAMDAEQREELEAIIRDLEE 3300
                          ...|.:.:...||....|......:..:..:..:.:|....|::||..|..
  Fly   382 --------------IPAETRSVRSQCQEKDRTVVLQQQQQELCSLTGLASEASSRLQSIIDRLLL 432

  Fly  3301 ENANLQAEYQQLCSKEQSGMPEDSNGMQHSSSSMTGLSGQGEQGQDMMAEAKLLRQHKGRLEARM 3365
            :||.|:.:.|.:.:.              |||.:                ::.|..|:..|   :
  Fly   433 QNAKLETQLQTVATA--------------SSSEI----------------SQFLSAHQCFL---L 464

  Fly  3366 QILEDHNRQLEAQLQRLRQLLDEPNGGGSSATSSGLPSAPGSALNSKPNTLQ------------- 3417
            ||:||..     ||.....:...|....:....|..|....:.|:|.....|
  Fly   465 QIIEDMR-----QLSHASAVTSPPPAPAAQVAPSAAPLVSSTFLSSSTPQRQMLFDMYAPVGANL 524

  Fly  3418 TRSVTASQLNTDSPAKMNQQNGHYEHNSKGIMLPGMNSEIQQQHAQLASLAAKHHQHQLSGALNA 3482
            |.|:..:.||.   :.:......|..|...:......|.:|..... .||.|........|||
  Fly   525 THSINGADLNR---SYLEANKSDYSLNDISLWFDQRRSSVQPGQGP-GSLPAPLPLPMPLGAL-- 583

  Fly  3483 LHQQQQQQLQQQPPQQQRSMMTGNGGMDISGGMQTSGGYLGDDGRPPPPPHSSLMQQQHQQHLNE 3547
                    |:|||         .|||                |||.....:..|:
  Fly   584 --------LEQQP---------ANGG----------------DGRDTEMVNFKLL---------- 605

  Fly  3548 NSSGLVTVITEQELESINDDLEDSSSSNTTNTTTT 3582
                         |..:.:.:|||.|.|...:..|
  Fly   606 -------------LHKVKEIVEDSYSDNAELSAAT 627

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.