DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dys and Dmd

DIOPT Version :9

Sequence 1:	NP_001036722.1	Gene:	Dys / 42327	FlyBaseID:	FBgn0260003	Length:	3598	Species:	Drosophila melanogaster
Sequence 2:	XP_017457398.1	Gene:	Dmd / 24907	RGDID:	2507	Length:	3682	Species:	Rattus norvegicus

Alignment Length:	3940	Identity:	1128/3940 - (28%)
Similarity:	1806/3940 - (45%)	Gaps:	797/3940 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ERQHIQKKTFTKWINSHLIDTQCTPVKDLFLDLRDGHRLLALLSTLTQTNLKPEKGRMRVHHINN 73
            ||:.:||||||||||:.........:.:||.||:||.|||.||..||...|..|||..|||.:||
  Rat    12 EREDVQKKTFTKWINAQFSKFGKQHIDNLFSDLQDGKRLLDLLEGLTGQKLPKEKGSTRVHALNN 76

  Fly    74 LNKVITEIQQHGVKLVNISSDDIVGGNAKLTLGLIWLIALEFNGQHLVKS-----HSSNGVEKSL 133
            :||.:..:|::.|.||||.|.|||.||.||||||||.|.|.:..::::|:     ..:|. ||.|
  Rat    77 VNKALQVLQKNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKTIMAGLQQTNS-EKIL 140

  Fly   134 LAWARQYTEPHGLQLN--DFSSSWSDGRAFLMILDAHVEEL---NLQAALQQHALKRLHLAFDLA 193
            |:|.|:.|..:. |:|  :|:||||||.|...::.:|..:|   | ....||.|.:||..||::|
  Rat   141 LSWVRESTRNYP-QVNVLNFTSSWSDGLALNALIHSHRPDLFDWN-SVVSQQSATQRLEHAFNIA 203

  Fly   194 HRHFKIEKLLDAEDVHTHKPDNKSIQMYVMCLYHAMESMRTRQQEQEQDEGQDQDPGRVPCTSIT 258
            .....||||||.|||.|..||.|||.||:..|:..:                   |.:|...:|.
  Rat   204 KCQLGIEKLLDPEDVATTYPDKKSILMYITSLFQVL-------------------PQQVSIEAIR 249

  Fly   259 DLDEVPLDN----------------------------DQTS-------------LGLYTSDSAGS 282
            :::.:|..:                            :|||             ...|.:.|..|
  Rat   250 EVEMLPRPSKVTREEHFQLHHQMHYSQQITVSLAQGYEQTSSSPKPRFKSYAFTQAAYVATSDSS 314

  Fly   283 MEQRSSGELKTHSMRPL-STATNASVEISGYQSALEAVLTLLLEDEQLLSQNLPDPQDFQTAKLQ 346
            .....|..|:....:.. |:.....|.:..||:|||.||:.||..|..|.......:|.:..|.|
  Rat   315 QSPYPSQHLEAPGSKSFGSSLIETEVNLDSYQTALEEVLSWLLSAEDTLRAQGEISKDVEEVKEQ 379

  Fly   347 FHENESFMLKLTEHQEYVGEALEEGSNLINESQKAGAGLSQEDQNEVRQQMVLLNERWETLRLRA 411
            ||.:|.||:.||.||..||..|:.||.|:.:.:     |:::::.||::||.|||.|||.||:.:
  Rat   380 FHAHEGFMMDLTSHQGLVGNVLQLGSRLVGKGK-----LTEDEETEVQEQMNLLNSRWECLRVAS 439

  Fly   412 LDVQAKILMRLAEFQKQKLEQLRQFLTSVEDRISHMSD--IGPTLEEAEKQLLEAQKLKADLSEQ 474
            ::.|:.:...|.:.|.|||::|..:||..|:|...|.:  :||.||:.:.|:.:.:.|:.||.::
  Rat   440 MEKQSNLHKVLMDLQNQKLKELDDWLTKTEERTKKMEEEPLGPDLEDLKCQVQQHKVLQEDLEQE 504

  Fly   475 QELVDSLSSMVVIVNDTSGNFND--LEDRLSALGERWSHVVKWSD----------LRKEKLQQYK 527
            |..|:||:.|||:|:::||:...  ||::|..||:||:::.||::          |:.::..:.:
  Rat   505 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICKWTEDRWILLQDILLKWQRFTEEQ 569

  Fly   528 CI-SRWLDAREQDLKLMES---RDVTDVGGITQRINELNYCAKDLLELQRYLIDLRQMVAATLQD 588
            |: |:||..:|..:|.:::   .|..::....|.|:.|....:...:....|..|.|.:.:.|::
  Rat   570 CLFSKWLSEKEDAMKNIQTSGFEDQNEMVSSLQNISALKIDLEKKKQSMEKLSSLNQDLLSALKN 634

  Fly   589 GDDKGERVLIQLESYEDRLDALKQIVE-----------------VQTVRIETKGFNFGRDRASYD 636
             ....:::.:.:|::..|.|.|.|.:|                 .||..:||......|::....
  Rat   635 -KSVTQKMEMWMENFAQRWDNLTQKLEKSSAQISQAVTTTQPSLTQTTVMETVTMVTTREQIMVK 698

  Fly   637 DSRVVRP--------EGWVDYQMIIRFGEDDSQEDDDEHDLASKKRKLRNADNF----------- 682
            .::...|        :..||.::..|...|.:    :.|...::...:..:..|
  Rat   699 HAQEELPPPPPQKKRQITVDSEIRKRLDVDIT----ELHSWITRSEAVLQSSEFAVYRKEGNISD 759

  Fly   683 -----NALENHIMEHFGYVQEVEQKLQQLQRQ---------SLRQQCELLKELQAENSR---RCG 730
                 ||:.....|.|..:|:..:..|.|..|         |:||..|.|      |||   .|.
  Rat   760 LKEKVNAIAREKAEKFRKLQDASRSAQALVEQMVNEGVNAESIRQASEQL------NSRWTEFCQ 818

  Fly   731 TLPELKKLYEVCELEDPSRNLLLEETHIKQLEQRYANLSQKLSSQQSESHTLLAKEKYYNSLTGF 795
            .|.|.....|.      ..|::.....::||||........|.:|.    |.|::.      |..
  Rat   819 LLSERVNWLEY------QNNIITFYNQLQQLEQMTTTAENLLKTQP----TTLSEP------TAI 867

  Fly   796 KLVLADSRDWYKQHAGSASGNELEQRLSHMESLASEISEAKTATEELDDNLIEWKQDFGLFYDSW 860
            |..|...:|...:.:.      |:.::..::..:..:.|.......||.:.:.:...|...:|..
  Rat   868 KSQLKICKDEVNRLSA------LQPQIERLKIQSLTLKEKGQGPMFLDADFVAFTNHFNYVFDGV 926

  Fly   861 HDMKQALQALIQ----QRGGESLSRQLKQIQDFVTKVSNQKVRVSNLEVMQEQQHFLNQL---LD 918
            ...::.||.:..    .|..|::|.....||....|:|...:.|:..|:|:|:...|..|   |.
  Rat   927 RAREKELQTIFDTLPPMRYQETMSSIRTWIQQSENKLSIPHLSVTEYEIMEERLGKLQALQSSLK 991

  Fly   919 EMES----LRLTYDNIPKHLIG----------EELQTAWNRLPEQLNERVIKQTTAIENLNHF-- 967
            |.::    |..|...|.|....          ||::..|.:|..||.|...|....:..|..|
  Rat   992 EQQNGFNYLNATVKEIAKKAPSEISQKYQSEFEEVEGRWKKLSTQLVEHCQKLEEHMNKLRKFQN 1056

  Fly   968 ----AAEYNAIIAMLRSAADSKLNGSDGASSQ---------DLRKLEIDVISARNFSEILIKEAE 1019
                ..::.|.:.:........|..::....|         |::.::..:.|.....:.:..|||
  Rat  1057 HKKTLQKWMAEVDVFLKEEWPALGDAEILKKQLKQCRLLVGDIQTIQPSLNSVNEGGQKIKSEAE 1121

  Fly  1020 PAQKESLQSQIRALNTLYDQV-EQVHREKKEQQTVLQSHIDLIQLRLKETDQWLT---------D 1074
            ......|:.:::.|||.:|.: .||:..|:..:..|...:.| |..|.|..:|:|         |
  Rat  1122 FEFASRLEKELKELNTQWDHICRQVYTRKEALKAGLDKTVSL-QKDLSEMHEWMTQAEEEYLERD 1185

  Fly  1075 LESNTPKSGISDIVNSNELFQSKSRFQTLKETCERETTQFRDLNERGGELLLQMDELQDQDRESR 1139
            .|..||          :||..:....:..||...::..:.:.|.|....::.|......:..:..
  Rat  1186 FEYKTP----------DELQTAVEEMKRAKEEALQKEAKVKLLTETVNSVISQAPPAAQEALKKE 1240

  Fly  1140 YGSLAKQF----TRINARWTEVTELVYAKTALLEHISTQLGEFKKFMVSETGYLDKLENKIRNTP 1200
            ..:|...:    ||:|.:         .||  ||.:.....|...::.....:|:::|.|::.|.
  Rat  1241 LETLTTNYQWLCTRLNGK---------CKT--LEEVWACWHELLSYLEKANKWLNEVELKLKATE 1294

  Fly  1201 ENAADAEEIMEELDDLENVLRSHSEEWLDKIQEIGNELIDNEFMADSIRRDIDETVQRWTQLQQQ 1265
            ...|.||||.|.|:.|||::. ||||..::|:.:...|.|...|.:.|..:::....||.:|.::
  Rat  1295 NVPAGAEEITEVLESLENLMH-HSEENPNQIRLLAQTLTDGGVMDELINEELETFNSRWRELHEE 1358

  Fly  1266 AKKRTELLEQKVSEAEQSEKCIVQFEKWLTRVDDILSDHLDNDVTIVDQPEEFQRLAHEFVANEK 1330
            |.::.:||||.:..|::.||.:...::.|..:|..|:.::.:.|.....|:|.|::..:..::|.
  Rat  1359 AVRKQKLLEQSIQSAQEIEKSLHLIQESLEFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEI 1423

  Fly  1331 NFKEISELIDEHTRNGKV-GAANRLQEQLNLMEVRFKYCQAKLSKCTAIQHSYESRLNRAYTDLR 1394
            :.:|:.:.......|.:| ...:..|::|..:.::|:..|...        ::|.||..:...|.
  Rat  1424 SLEEMKKHNQGKDANQRVLSQIDVAQKKLQDVSIKFRLFQKPA--------NFEQRLEESKMILD 1480

  Fly  1395 NVERSTEVVDVASAGPNTVQTQYQKCLQIYRTLSEIKSEIESTIKTGRRVCEDRYTKSPKQLSQR 1459
            .|:.....::..|.....||:|...|:.:|::|||:|||:|..|||||::.:.:.|::||:|.:|
  Rat  1481 EVKMHLPALETKSVEQEVVQSQLSHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDER 1545

  Fly  1460 IDALKHLYNTLGENVTQSKATLERLLTLARQLEECFDSADNLIRRFESPQEVHDRNSILLEFEDV 1524
            :.|||..||.||..||:.|..||:.|.|:|::.:
  Rat  1546 VTALKLHYNELGAKVTERKQQLEKCLKLSRKMRK------------------------------- 1579

  Fly  1525 LRRCEDHYNEYNKSCDQSCMVET----RQRIDGL------KATYHKLTSADIIKRLTEMKTTLQN 1579
                     |.|...:.....:|    |..::|:      :..:.|.|..:|.|:...:|:..:.
  Rat  1580 ---------EMNVLTEWLAATDTELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKAHLKSVTEL 1635

  Fly  1580 LDNISLETLRAMEHDLKEINVPSNPEIEKLQQQVIAIVVDVLKTRFNEATTLAARNTSSPDNDDT 1644
            .|  ||:|:...:..|.|      .::..|....||:.     :|..|...|........::.|.
  Rat  1636 GD--SLKTVLGKKETLVE------DKLTLLNSNWIAVT-----SRVEEWLNLLLEYQKHMESFDQ 1687

  Fly  1645 E-------IVVVSDTVRQRRARTPQSGESPSSAHTSSSESPTKGVENSPGAVGDQVMP------- 1695
            .       |:...:.:.:...|.||..|.    .....::....:.....|..||...
  Rat  1688 NVEHITKWIIHTDELLDESEKRKPQQKED----ILKRLKAEMNDIRPKVDATRDQAAKLMANRGD 1748

  Fly  1696 ---DLLPPQTFRLAESSTLFSQISLNPQKVTNTPPPKPAKTKRKAPSSPAQVVEIRVKNIQNDKM 1757
               .::.||   ::|.:..|:.||            ...||.:         ..|.:|.::....
  Rat  1749 YCRKIVEPQ---ISELNRRFAAIS------------HRIKTGK---------ASIPLKELEQFNS 1789

  Fly  1758 SVQNIDLEPQQGEIVDTVNILESVEPFVPEYVETVQIVDLSEDSDSSV------------RVDSQ 1810
            .:|.: |||.:.||...||:.|  |.|..         |:|||::.:|            |:..:
  Rat  1790 DIQKL-LEPLEAEIQQGVNLKE--EDFNK---------DMSEDNEGTVNELLQRGDNLQQRITDE 1842

  Fly  1811 G-------------------KEMRRSKSKHSLNETPLPKVSDNDEDSAEQEEDLLRPSAENTSTP 1856
            .                   |::|..:.|.:|      ::|........|.:|||:...|
  Rat  1843 RKREEIKLKQQLLQTKHNALKDLRSQRRKKAL------EISHQWYQYKSQADDLLKCLDE----- 1896

  Fly  1857 FLRVEKRRISFDE---KRKRVANERDILRDSEE-----EEPKTPDTPRAAQVSKP------KRWR 1907
               :||:..|..|   :||....:|::.:..||     .:.::.....||...:|      ||||
  Rat  1897 ---IEKKLASLPEPRDERKIKEIDRELQKKKEELNAVRRQAESLSENGAAMAVEPTQIQLSKRWR 1958

  Fly  1908 QLQPEMDALEPESPGRDSFYSPDKESGF------DAEPLVFSDDEDIP--------RFSLEMTST 1958
            ::              :|.::..:...|      ..|.:|.: .||:|        .:..|::..
  Rat  1959 EI--------------ESNFAQFRRLNFAQIHTLHEETMVVT-TEDMPLDVSYVPSTYLTEISHI 2008

  Fly  1959 IDSDSDTSRIMTPSTKNPNPF------------LSKVLESLSSPVD---------------DSNV 1996
            :.:.|:..:::.....|...|            :.:.|:.:|..:|               ...|
  Rat  2009 LQALSEVEQLLNAPELNAKDFEDLFKQEESLKNIKENLQQISGRIDVIHKKKTAALQSATPMERV 2073

  Fly  1997 TLKSPIS------EEQPQNLDDRVREFDKQA---KQMIYKLKLTKA---KIEQCHESE------- 2042
            .|:..:|      |:..:...:|...||:..   :...|.:|:...   .:||..:..
  Rat  2074 KLQEAVSQMDFHWEKLNRMYKERQGRFDRSVEKWRHFHYDMKVFNQWLNDVEQFFKKTQNPENWE 2138

  Fly  2043 -------AEDLRLLIAPDAA---TLISQGDSLVLETHGR-----QGSISRLVMRTQII---LREQ 2089
                   .::|:..|....|   ||.:.|:.::.::...     |..:..|.:|...:   |.|:
  Rat  2139 HAKYKWYLKELQDGIGQRQAVVRTLNATGEEIIQQSSKTDANILQEKLGSLSLRWHEVCKELAER 2203

  Fly  2090 FREVQQARS----------------KTSGSGAPAPPLDSVNIEE------LVTKG-------LRR 2125
            .:.|::.::                :.:.:.|..||.|...::|      |:|:.       |::
  Rat  2204 RKRVEEQKNVFSEFQRDLNEFVSWLEEADNIATTPPGDEEQLKEKLEQVKLLTEELPLRQGILKQ 2268

  Fly  2126 IN-----VLIEKTVDLKSSTDLEKRMEDINERHDDLQVIVSAIGKNAQMPKVTPLMMNEIE---K 2182
            :|     ||:...:..:....|||:::..|     ||.|        ::.:..|....|:|   |
  Rat  2269 LNETGGAVLVSAPIRPEEQDKLEKKLKQTN-----LQWI--------KVSRALPEKQGELEVHIK 2320

  Fly  2183 TKNNLIAHADSIELSLTELRN-----------GP-------------------RISNG----KER 2213
            .........|.:.|.|:.:||           ||                   .:|.|    ||:
  Rat  2321 DFRQFEEQLDHLLLWLSPIRNQLEIYNQPSQPGPFDLKETEVTVQAKQPDVERLLSKGQHLYKEK 2385

  Fly  2214 PDASSAATM--SCRSEY-----------NNEP------SGTGALA-------------------- 2239
            |........  ..|||:           ..:|      |.|||.|
  Rat  2386 PSTQPVKRKLEDLRSEWEAVNHLLWELRTKQPDRAPGLSTTGASASQTVTVVTQPVDTKETVISK 2450

  Fly  2240 --------------GSFDKSVLQISDWLTWEQNMIKIQSVLVDDGDAVRLAIEKQEKVLRELKMK 2290
                          ..|:::..:::|||:....:||.|.|:|.|.:.:...|.||:..|::|:.:
  Rat  2451 LEMPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQR 2515

  Fly  2291 KPQLNELVHTAEVLKGDVKRQQLQEKELKQFSLAPHCSADLDYMRCCLKVTRLREHWDETSQCVL 2355
            :|||.||:..|:.||.....|:           |.....|        ::.|::..|||..:.:.
  Rat  2516 RPQLEELITAAQNLKNKTSNQE-----------ARTIITD--------RIERIQIQWDEVQEQLQ 2561

  Fly  2356 QRAAQLKNMLSDS-QRFEAKRLELEKWLARMEQRAERMGTIATTADILEAQQKEQKSFHAELHQN 2419
            .|..||..||.|| |..|||. |.|:.:.:...:.:.......|.|.::.:..|.|....:|.|.
  Rat  2562 NRRQQLNEMLKDSTQWLEAKE-EAEQVIGQARGKLDSWKEGPHTMDAIQKKITETKQLAKDLRQR 2625

  Fly  2420 KQHFDIFNELTQKLIAVYPNDDTTRIKKMTEVINQRYANLNSGVINRGKQLHAAVHSLQSFDRAM 2484
            :.:.|:.|:|..||:..|..|||.::..:||.||..:.|:...|..|...|......||.|...:
  Rat  2626 QINVDVANDLALKLLRDYSADDTRKVHMITENINTSWGNILKRVSEREAALEETQRLLQQFPLDL 2690

  Fly  2485 DQFLAFLSETETLCENAESDIERNPLM-------------FKDLQSEIETHRVVYDRLDGTGRKL 2536
            ::|||:::|.||.. |...|..|...:             ::|||.|||.|..:|..||..|:|:
  Rat  2691 EKFLAWITEAETTA-NVLQDASRKEKLLEDSRGVRELMKPWQDLQGEIEAHTDIYHNLDENGQKI 2754

  Fly  2537 LGSLTSQEDAVMLQRRLDEMNQRWNNLKSKSIAIRNRLESNSEHWNALLLSLRELTEWVIRKDTE 2601
            |.||...::|.:||||||.||.:|:.|:.||:.||:.||.:|:.|..|.|||:||..|:..||.|
  Rat  2755 LRSLEGSDEAPLLQRRLDNMNFKWSELRKKSLNIRSHLEVSSDQWKRLHLSLQELLVWLQLKDDE 2819

  Fly  2602 LSTLGLGPVRGDAVSLQKQLDDHKAFRRQLEDKRPIVESNLTSGRQYIANEAAVSDTSDTEANHD 2666
            ||.  ..|:.||..::|||.|.|:||:|:|:.|.|::.|.|.:.|.::..:    .....|..:
  Rat  2820 LSR--QAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQ----PLEGLEKLY- 2877

  Fly  2667 SDSRYMSAEEQSRELTRSIRREVGKLSEQWNNLIDRSDNWKHRLDEYMTKMRQFQKILEDLSSRV 2731
            .:.|.:..||:::.:||.:|::..:::.:|:.|...|.:|:.::||.:.::::.|:..::|..::
  Rat  2878 QEPRELPPEERAQNVTRLLRKQAEEVNTEWDKLNLHSADWQRKIDEALERLQELQEAADELDLKL 2942

  Fly  2732 ALAEQTKTSWLPPSS--VGEANEQMQQLQRLRDKMTTASALLDDCNEQQSFFTANQVLVPTPCLS 2794
            ..||..|.||.|...  :....:.:::::.||.::......::..|:.....|...:.:....||
  Rat  2943 RQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVNHVNDLAHHLTTLGIQLSPYNLS 3007

  Fly  2795 KLEDLNTRMKLLQIAMDERQKVLCQAGAQQTHENGDDGRTTSNSGTIGPLPN--LGQSVKPPWER 2857
            .|||||||.:|||:|:::|        .:|.||...|         .||...  |..||:.||||
  Rat  3008 ILEDLNTRWRLLQVAVEDR--------VRQLHEAHRD---------FGPASQHFLSTSVQGPWER 3055

  Fly  2858 ATTAANVPYYIDHERETTHWDHPEMIELMKGLADLNEIRFSAYRTAMKLRSVQKRLALDRISMST 2922
            |.:...|||||:||.:||.||||:|.||.:.|||||.:||||||||||||.:||.|.||.:|:|.
  Rat  3056 AISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSA 3120

  Fly  2923 ACESFDRHGLRAQNDKLIDIPDMTTVLHSLYVTIDK-----IDLTLMLDLAINWILNVYDSQRTG 2982
            ||::.|:|.|: |||:.:||..:...|.::|..:::     :::.|.:|:.:||:|||||:.|||
  Rat  3121 ACDALDQHNLK-QNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTG 3184

  Fly  2983 QIRVLSFKVGLVLLCKGHLEEKYRYLFRLVADTDRRADQRRLGLLLHDCIQVPRQLGEVAAFGGS 3047
            :|||||||.|::.|||.|||:||||||:.||.:....|||||||||||.||:||||||||:||||
  Rat  3185 RIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGS 3249

  Fly  3048 NIEPSVRSCLEQAGISQEAIDGNQDISIELQHFLGWLQHEPQSLVWLPVLHRLAAAEAAKHQAKC 3112
            |||||||||.:.|         |....||...||.|::.||||:||||||||:||||.|||||||
  Rat  3250 NIEPSVRSCFQFA---------NNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKC 3305

  Fly  3113 NICKEYPIVGFRYRCLKCFNFDMCQKCFFFGRNAKNHKLTHPMHEYCTTTTSTEDVRDFTRALKN 3177
            |||||.||:|||||.||.||:|:||.|||.||.||.||:.:||.||||.|||.||||||.:.|||
  Rat  3306 NICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKN 3370

  Fly  3178 KFKSRKYFKKHPRVGYLPVQSVLEGDALESPAPSPQHTTHQLQNDMHSRLEMYASRLAQVEYGGT 3242
            ||::::||.||||:||||||:|||||.:|:||.||| .:|   :|.|||:|.||||||::| ...
  Rat  3371 KFRTKRYFAKHPRMGYLPVQTVLEGDNMETPASSPQ-LSH---DDTHSRIEHYASRLAEME-NSN 3430

  Fly  3243 GS----NSTPDS--DDEHQLIAQYCQALPGTSNGSAPKSPVQVMAAMDAEQREELEAIIRDLEEE 3301
            ||    :.:|:.  ||||.||..|||:|...|..|.|:||.|::.::::|:|.|||.|:.|||||
  Rat  3431 GSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEE 3495

  Fly  3302 NANLQAEYQQLCSKEQSGMPEDSNGMQ--HSSSSMTGLSGQGEQGQDMMAEAKLLRQHKGRLEAR 3364
            |.||||||.:|  |:|    .:..|:.  .|...|...|.|..:..:::||||||||||||||||
  Rat  3496 NRNLQAEYDRL--KQQ----HEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEAR 3554

  Fly  3365 MQILEDHNRQLEAQLQRLRQLLDEP------NGGGSSATSSGLPSAPGSA--------------- 3408
            ||||||||:|||:||.||||||::|      ||...|:.|:.|..:..|.
  Rat  3555 MQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESM 3619

  Fly  3409 ----LNSKPNTLQT-RSVTASQLNTDSPAKMNQQNGHYEH 3443
                |.|.|....| ......|||...|:......|...|
  Rat  3620 GEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHNVGSLFH 3659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dys	NP_001036722.1	CH	13..111	CDD:278723	54/97 (56%)
		CH	129..225	CDD:278723	45/100 (45%)
		SPEC	312..525	CDD:238103	82/226 (36%)
		SbcC	<325..957	CDD:223496	172/723 (24%)
		Smc	<816..1591	CDD:224117	186/835 (22%)
		SPEC	1174..1365	CDD:238103	48/191 (25%)
		SPEC	1289..1485	CDD:295325	55/196 (28%)
		SPEC	2369..2576	CDD:238103	72/219 (33%)
		SPEC	2477..2714	CDD:238103	88/249 (35%)
		WW	2852..2882	CDD:238122	18/29 (62%)
		EF-hand_2	2883..2997	CDD:286194	58/118 (49%)
		EF-hand_3	3001..3100	CDD:286195	62/98 (63%)
		ZZ_dystrophin	3110..3158	CDD:239074	33/47 (70%)
Dmd	XP_017457398.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2085
eggNOG	1	0.900	-	-		E2759_KOG4286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1367	1.000	Inparanoid score	I116
OMA	1	1.010	-	-		QHG46633
OrthoDB	1	1.010	-	-		D46278at33208
OrthoFinder	1	1.000	-	-		FOG0001792
OrthoInspector	1	1.000	-	-		otm46205
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11915
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2389
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980