DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dys and dmd.3

DIOPT Version :9

Sequence 1:	NP_001036722.1	Gene:	Dys / 42327	FlyBaseID:	FBgn0260003	Length:	3598	Species:	Drosophila melanogaster
Sequence 2:	XP_031752861.1	Gene:	dmd.3 / 105946662	XenbaseID:	XB-GENE-5813243	Length:	3683	Species:	Xenopus tropicalis

Alignment Length:	3933	Identity:	1144/3933 - (29%)
Similarity:	1880/3933 - (47%)	Gaps:	773/3933 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DERQHIQKKTFTKWINSHLIDTQCTPVKDLFLDLRDGHRLLALLSTLTQTNLKPEKGRMRVHHIN 72
            |||:.:|:||||||||:........|::|||.||:||.|||.||..||...|..|||..|||.:|
Frog    28 DEREDVQRKTFTKWINAQFAKFGKHPIEDLFSDLQDGRRLLDLLEGLTGQKLVKEKGSTRVHALN 92

  Fly    73 NLNKVITEIQQHGVKLVNISSDDIVGGNAKLTLGLIWLIALEFNGQHLVKSHSSN----GVEKSL 133
            |:||.:..:|::.:.||||.|.|||.||.||||||||.|.|.:..:.::|...::    ..||.|
Frog    93 NVNKALQVLQKNNIDLVNIGSADIVDGNHKLTLGLIWSIILHWQVKDVLKGIMADLQQTNTEKIL 157

  Fly   134 LAWARQYTEPHGLQLN--DFSSSWSDGRAFLMILDAHVEEL-NLQAALQQHALKRLHLAFDLAHR 195
            |:|.||.|..:. |:|  :|:||||||.||..::.:|..:| ...:.|.|.||:||..||:.|.|
Frog   158 LSWVRQSTRNYP-QVNVINFTSSWSDGLAFNALIHSHRPDLFEWNSVLCQSALERLDHAFNAAQR 221

  Fly   196 HFKIEKLLDAEDVHTHKPDNKSIQMYVMCLYHAMESMRTRQQEQEQDEGQDQDPGRVPCTSITDL 260
            |..|..|||.:|:.|..||.|||.|||..|:.|:....:.:..||.|        .:|...:|..
Frog   222 HLGIANLLDPDDIATAHPDKKSILMYVTSLFQALPQQVSIESLQELD--------TLPRRMVTPE 278

  Fly   261 DEV-PLDNDQTSLGLYTSDSAGSM-------------------------EQRS----SGELKTHS 295
            ..| |.|....|..:..|.:.||:                         :|:|    ..:|:...
Frog   279 PHVKPYDQQHFSQHITVSVAEGSVHTPSPPPKPRYKSYAYTQAAYVMYPDQKSRPFPQQQLEGFD 343

  Fly   296 MRPLST-ATNASVEISGYQSALEAVLTLLLEDEQLLSQNLPDPQDFQTAKLQFHENESFMLKLTE 359
            .||..| ......::..|||:||.||:.||..|.:|........:.:..|.|||.:|.||::||.
Frog   344 NRPFGTLVREPQADLESYQSSLEEVLSWLLSAEDILQSQKTISNNVEEVKDQFHTHEGFMMELTS 408

  Fly   360 HQEYVGEALEEGSNLINESQKAGAGLSQEDQNEVRQQMVLLNERWETLRLRALDVQAKILMRLAE 424
            ||..||..|:.||.|:...:     ||.:::||:::||.|||.|||:|||.:::.|:.:..||.:
Frog   409 HQGNVGNVLQAGSQLLVTGK-----LSDDEENEIQEQMNLLNTRWESLRLASMERQSNLHRRLMD 468

  Fly   425 FQKQKLEQLRQFLTSVEDRISHM-SDIGPTLEEAEKQLLEAQKLKADLSEQQELVDSLSSMVVIV 488
            .|.|:|:||..:|:..|:|...| :::||.||:.::|:.|.:.|:.||.::|..|:||:.|||:|
Frog   469 LQNQQLQQLSDWLSQTEERTRKMDAELGPDLEDIKRQIEEHKVLQDDLEQEQIRVNSLTHMVVVV 533

  Fly   489 NDTSGN--FNDLEDRLSALGERWSHVVKWSD----------LRKEKLQQYKCI-SRWLDAREQDL 540
            :::||.  ..||||:|..||.||:.:.:|::          |:.::..:.:|: ..||..:|:.:
Frog   534 DESSGEKATADLEDQLQHLGNRWAAICRWTEDRWVFLQEILLKWQRFAEEQCLFDVWLTEKEEAV 598

  Fly   541 KLMESRDVTDVGGITQRINELNYCAKDLLELQRYLID----LRQMVAATLQDGDDKGERVLIQLE 601
            ..:.:....|...:...:.:| ...|..||:::..:|    |.|.:.:.|:: ....::...:||
Frog   599 NNINTASFKDQNEMRSNLRKL-AILKGELEMKKTTMDTLYSLNQDLTSALKN-KSVSQKHEARLE 661

  Fly   602 SYEDRLDALKQIVEVQTVRIE----TKGFNFGRDRASYDDSRVVRPEGWVDYQMIIRFGEDDSQE 662
            ::..|.|.|.|.:|..:.:|.    |...:..:.......:.|...|     :::::..:|:...
Frog   662 NFTQRWDNLVQKLESTSKQISQAATTTQTSLTQTTVKETVTMVTTRE-----EILVKHAKDELPP 721

  Fly   663 DDDEHDLASKKRKLRNADNFNALENHIMEHFGYVQEVEQKLQQLQRQSLRQQCELLKELQAENSR 727
            ...:     |||::       .:|:.:.:.|      :..|.:|.....|.:. :|:..:....|
Frog   722 PPPQ-----KKRQI-------LVESELRKRF------DVDLTELHSWMTRSEA-VLQSSEFAVYR 767

  Fly   728 RCGTLPELKKLYEVCELEDPSRNLLLEETH------IKQLEQRYANL------SQKLSSQQSESH 780
            :.|.|.:|.|..:..|.|.|.::..|::.:      ::|:.....|.      ||.|:|:.:|..
Frog   768 KEGDLTDLTKKVKAIEKEKPDKHRKLQDANRNTQALVEQMLSDGVNADSIKQSSQHLNSRWTEFC 832

  Fly   781 TLLAKE----KYYNSLTGF---------KLVLADSRDWYKQHAGSASGN------ELEQRLSHME 826
            .||::.    :|.||:..|         |::.|:  :|.|......|..      :.:..::.:.
Frog   833 QLLSERISWLEYQNSILAFYSQLQQLEQKVISAE--NWLKAQTQPTSETVKMHLAKCKDEVARLS 895

  Fly   827 SLASEISEAK---TATEELDDNLIEWKQDFGLFYDSWHDMKQALQALIQQ-----------RGGE 877
            :|..||...:   |..:|.:...:..:.|...|.:.::.:..:||:..:|           :..|
Frog   896 ALKPEIGSLQVQGTELKEKEQRPMFLEADVAAFVNHYNQVLSSLQSREKQLQNILDSLPPTQYTE 960

  Fly   878 SLSRQLKQIQDFVTKVSNQKVRVSNLEVMQE------------QQH-----FLNQLLDEMESLRL 925
            .:|..|..||...||::..:|.|:..|:|::            |:|     :|::..:|: |.:.
Frog   961 KMSTILMWIQQSETKLAIPQVTVTECEIMEQRLRELKALQSSLQEHQADMNYLSKTAEEL-SRKA 1024

  Fly   926 TYDNIPKHLIGEEL-QTAWNRLPEQLNERVIKQTTAIENLNHF----------AAEYNAII---- 975
            ..|...|:|...:| |..|..|..||..:..|....:..|..|          .||.|..:
Frog  1025 PTDVKQKYLTEIDLTQNRWKTLSNQLVGQCQKLEELLSTLKQFQNDMKTLKKWMAEVNVFLNEEW 1089

  Fly   976 -AMLRSAADSKLNGSDGASSQDLRKLEIDVISARNFSEILIKEAEPAQKESLQSQIRALNTLYDQ 1039
             |:..|.|..|......|...|::.::..|.|..:..:.||.:|||.....|:..::.||   ||
Frog  1090 PALGDSEALEKQLEQCSALVNDIQTIQPSVTSVNDVGQKLISKAEPVYSSKLKQDLKNLN---DQ 1151

  Fly  1040 VEQVHREKKEQQTVLQSHID-LIQLR--LKETDQWLT---------DLESNTPKSGISDIVNSNE 1092
            .:.:.|:...::..|:..:| .|.||  |.|..:|:|         |.|..||:
Frog  1152 WDHICRQANAKKAALKGGLDKTISLRKDLSEMQEWVTQAEHEYSERDFEYKTPE----------- 1205

  Fly  1093 LFQSKSRFQTLKETCERETTQFRDLNERGGELLLQMDELQD---QDRESRYGSLAKQFTRINARW 1154
              :.:...:.||...| |..|..|      ::.|..|.:.:   ....:.:..|.|:...:...:
Frog  1206 --ELQKALEELKRATE-EAAQKED------KVKLLKDSVNNFIATAPPAAHEPLKKELEVLVTNY 1261

  Fly  1155 TEVTELVYAKTALLEHISTQLGEFKKFMVSETGYLDKLENKIRNTPENAADAEEIMEELDDLENV 1219
            ..:...:..|...|:.:.....|...::.:|..:||::|.|::.|......||||.|.|..:|.:
Frog  1262 ERLCSRLNGKCQTLKEVWACWCELLSYLEAENKWLDEVEAKLKTTENVKGGAEEISEALKSIEKI 1326

  Fly  1220 LRSHSEEWLDKIQEIGNELIDNEFMADSIRRDIDETVQRWTQLQQQAKKRTELLEQKVSEAEQSE 1284
            :: |.|:..::|:|:...|.|...|.:.|...:::....|.::||:|.:|.::|||.:..|::::
Frog  1327 MK-HPEDNRNQIRELAQTLTDGGVMDELINEKLEKFNTHWEEVQQEAVRRQKVLEQSIQSAQETD 1390

  Fly  1285 KCIVQFEKWLTRVDDILSDHLDNDVTIVDQPEEFQRLAHEFVANEKNFKEISELIDEHTRNGKVG 1349
            |.|...::.|...|..|:.::.:.:.....|:|.|::..:.:::|.:..|:.:      ||....
Frog  1391 KAIRMIQEALNTTDRQLTAYIADRIDAAQVPQEAQKIQSDLMSHEISLDEMKK------RNQGKE 1449

  Fly  1350 AANRLQEQLNLMEVRFKYCQAKLSKCTAIQHSYESRLNRAYTDLRNVERSTEVVDVASAGPNTVQ 1414
            .:.::..|:.:.:.:|:....|. :......::|.||..:...|..|.....|:::.|.....||
Frog  1450 MSKKVLSQIEIAQKKFQEVSTKF-RLFQKPANFEQRLIESKRILDEVTFELPVLEIKSIEQEVVQ 1513

  Fly  1415 TQYQKCLQIYRTLSEIKSEIESTIKTGRRVCEDRYTKSPKQLSQRIDALKHLYNTLGENVTQSKA 1479
            ||..:|:::|:.|||:|||:|:.|||||::.:.:.|::||.|.:|:.|||..||.||..||:.|.
Frog  1514 TQLDQCMKLYKILSEVKSEVETVIKTGRQIVQKQQTENPKDLDERLTALKMQYNELGAKVTEGKQ 1578

  Fly  1480 TLERLLTLARQLEECFDSADNLIRRFESPQEVHDRNSIL--LEFEDVLRRCEDHYNEYNKSCDQS 1542
            .||:.|.|:|:|.:                   :.||:.  |...||
Frog  1579 NLEKCLKLSRKLRK-------------------EMNSLTDWLAATDV------------------ 1606

  Fly  1543 CMVETRQRIDGLKAT------YHKLTSADIIKRLTEMKTTLQNLDNI--SLETLRAMEHDLKE-- 1597
             .|..|..::|:.:.      :.|.|..::.||..::|    |:.:|  ||.|:...||:|.:
Frog  1607 -EVTKRSAVEGMPSNLAEEIGWSKSTQKEMEKRQQQLK----NVHDIGDSLRTVLGGEHNLVDDK 1666

  Fly  1598 --------INVPS------------NPEIEKLQQQVIAIVVDVLKTRFNEATTLAARN-TSSPDN 1641
                    :.|.|            :.|:|...|.|..|     ||..|:|.:|...: ...|..
Frog  1667 LSLLHSNWVAVTSRAEEWFRLLLQYHSEMESFDQDVATI-----KTWMNQAESLLDESEKQKPQQ 1726

  Fly  1642 DDTEIVVVSDTVRQRRARTPQSGESPSSAHTSSSESPTKGVENSPGAVGDQVMPDLLPPQTFRLA 1706
            .:..:.|:...:...:.:.....|:.....|:......|.||.                   :|:
Frog  1727 REETLKVIKSELNDMQPKKDSMHENAEELMTNRGAHCRKMVET-------------------KLS 1772

  Fly  1707 ESSTLFSQISLNPQKVTNTPPPKPAKTKRKAPSSPAQVVEIRVKNIQNDKMSVQNIDLEPQQGEI 1771
            :....|:.||   |::         |:.:...||         |.::.....:|.: |||.:.||
Frog  1773 DLDKRFNAIS---QRI---------KSGKALVSS---------KELEQFNSDMQKL-LEPLEAEI 1815

  Fly  1772 VDTVNILESVEPFVPEYVETVQIVDLSEDSDSSVR-VDSQGKEMRRSKSKHSLNETPLPKVSDND 1835
            ...||..|  |.|..         |:|||::..|: :..:|..:::             |::|..
Frog  1816 QLGVNPTE--EDFNK---------DMSEDNEEPVKELLLRGNNLQQ-------------KITDEK 1856

  Fly  1836 E-DSAEQEEDLLRPSAENTSTPFLRVEKRRISFD-----EKRKRVANERDILRDSEEEEPKTPDT 1894
            : :..:.::.||: |..|| ...||.::|:.:.:     .:.||.|:  |:|:..::.|.|....
Frog  1857 KCEEIKLKQQLLQ-SKHNT-LKILRTQRRKKALEISHQWYQYKRQAD--DLLKCLDDIERKIASL 1917

  Fly  1895 P---------------------------RAAQVSKP--------------KRWRQLQPEMDALEP 1918
            |                           :|..:||.              |||::::.:.
Frog  1918 PDPKDNQKLKEIDGELEKKKEELISVHRQAESLSKEGAGKAVEPTLIQLNKRWKEIESKF----- 1977

  Fly  1919 ESPGRDSFYSP----DKESGFDAEPLVFSDDEDIP-RFSLEMTSTIDSDSDTSRIMTPSTKNPNP 1978
             :|.|...|:.    .:|:.:.....:..:...:| .:..|:...:.|.::...::..|..|...
Frog  1978 -APFRRLHYAQIQTVPEETTYSMSEGIRVETVHVPSSYLAEIARLLQSIAEVGLLLDSSCLNKKD 2041

  Fly  1979 F--LSKVLESLSSPVDDSNVTLKSPI--------------SEEQPQNLDDRVRE--FDKQAKQMI 2025
            .  |:|..|.|.: :.||...|...:              |..:.:.:.|::.:  |:.:....:
Frog  2042 CEDLAKQQECLKN-IKDSLGRLSGQMEVIQNKKKAVMQCASPRENERIQDKLSDLNFEWENVNKL 2105

  Fly  2026 YKLKLTKAKIEQCHE----------------SEAEDLRLLIAPD--------------------- 2053
            ||.:  :.|.::|.|                :|||    ||..|
Frog  2106 YKDR--QMKHDRCMEKWMTLQDNMNHFNHWLNEAE----LILSDIPGDGKDSEKFKHQVKELEDG 2164

  Fly  2054 --------------AATLISQGDSLVLETHGRQGSISRLVMRTQII---LREQFREVQQARSKTS 2101
                          ...:|||  |...||...:..:..|..|..|:   :.|:.|.:::.:.|..
Frog  2165 IGQQQTFVRALNVSGGEIISQ--SSPTETADIRDKLESLNSRWHIVNRKINERRRRLEEEKKKLY 2227

  Fly  2102 G------------------SGAPAPPLDSVNIEELVTK-------------GLRRIN-----VLI 2130
            |                  :..|..|.:.:.:.||..|             .|:::|     .|.
Frog  2228 GLQEDLNKFCIWLEDAEGIARQPTEPGNELQLNELYEKVKFTAEELLPRKEFLKQLNEAGGTALG 2292

  Fly  2131 EKTVDLKSSTDLEKRMEDINER--------HDDLQVIVSAIGKN-----AQMPKVTPLMMN---- 2178
            ..|:..|....:|..:::.|:|        ||..:.|...: ||     .|:.::|..:.:
Frog  2293 STTISPKEKKKIESGLKEANQRWIKVSKDLHDKQKEIEDEL-KNLSLFELQLNQLTLWVSSVKDQ 2356

  Fly  2179 -------------EIEKTKNNLIA---HAD-------------------------------SIEL 2196
                         :|::|:..::|   |.:                               ::.|
Frog  2357 LQFYNQVGRPGAFDIKETEEAILAKQPHVEGILSKGHHLYTKEPAPYVLKQKLDDLQTEWNTVNL 2421

  Fly  2197 SLTELRNGPRIS----------------NGKERPDASSAATMSCRSEYNNEPSGTGALAGSFDKS 2245
            .|.||:..|.::                .|...|.|...:::...         ..||| .|:::
Frog  2422 LLQELKRRPAVAAPGGGQTVSVVTQTLVTGSTVPSADMPSSLLLE---------VPALA-EFNRT 2476

  Fly  2246 VLQISDWLTWEQNMIKIQSVLVDDGDAVRLAIEKQEKVLRELKMKKPQLNELVHTAEVLKGDVKR 2310
            ..:::||||....::|.|.|.|.|.:.:...|.||:..|::|:.::|.|.|.:..|:.||.....
Frog  2477 CAELTDWLTLLDRVLKAQIVTVGDVEEINEMIIKQKTTLQDLEKRRPHLEERITAAQNLKNKTSN 2541

  Fly  2311 QQLQEKELKQFSLAPHCSADLDYMRCCLKVTRLREHWDETSQCVLQ-RAAQLKNMLSDSQRFEAK 2374
                          |...|.:..     ::.:::..|:|. ||.|| |..||:.||.||.::...
Frog  2542 --------------PEARAVITD-----RIDKIQNQWEEV-QCHLQNRRLQLQEMLKDSNQWIEA 2586

  Fly  2375 RLELEKWLARMEQRAERMGTIATTADILEAQQKEQKSFHAELHQNKQHFDIFNELTQKLIAVYPN 2439
            |.|.::.:.:.:.|.:....|:.|.:.|:.|..:.|.|..||.|.:.:.|..|:|..||:..|..
Frog  2587 RHEADQVIEKAKNRTDSWKEISYTVEALKNQNSDLKQFSKELQQWQINVDAANDLALKLLRDYST 2651

  Fly  2440 DDTTRIKKMTEVINQRYANLNSGVINRGKQLHAAVHSLQSFDRAMDQFLAFLSETETLCENAESD 2504
            |||.:::.|.:.||..:|.:|..|..|...|.||:..||.|...:::|||:|:|.||.....:..
Frog  2652 DDTRKVELMKDNINATWARINKRVTERDAALEAALRLLQQFYLDLEKFLAWLTEAETTANVLQDA 2716

  Fly  2505 IERNPLM------------FKDLQSEIETHRVVYDRLDGTGRKLLGSLTSQEDAVMLQRRLDEMN 2557
            ..::.::            :::||.||:.|..|:..||..|:|:|.||...:|.|:||||||.||
Frog  2717 THKDGVLEDTRGLRELMNQWQNLQEEIDGHTEVFHSLDENGQKMLRSLEGSDDGVLLQRRLDNMN 2781

  Fly  2558 QRWNNLKSKSIAIRNRLESNSEHWNALLLSLRELTEWVIRKDTELSTLGLGPVRGDAVSLQKQLD 2622
            .|||.|:.||:.||:.||:::|||..|.:||:||..|:..|:.||..  ..|:.||...:|.|::
Frog  2782 IRWNELRKKSLNIRSHLEASTEHWKRLHVSLQELLAWLQMKNEELKQ--QAPIGGDVPKVQTQIE 2844

  Fly  2623 DHKAFRRQLEDKRPIVESNLTSGRQYIANEAAVSDTSDTEANHDSDSRYMSAEEQSRELTRSIRR 2687
            :|:||:|:::.|.|::.:.:.:.|.::.::     .|:|......:.:....|||.|.::|.:::
Frog  2845 NHRAFKREIKTKEPVIMNAIDTVRIFLDDQ-----PSETMERMHQEPKEAQTEEQFRNISRVLQK 2904

  Fly  2688 EVGKLSEQWNNLIDRSDNWKHRLDEYMTKMRQFQKILEDLSSRVALAEQTKTSWLPPSS--VGEA 2750
            :|..:|.:|:.|..||.:|:.:|||.:.::::.|:.:::|..::..||..|.||.|...  :...
Frog  2905 QVDDVSTEWDKLNLRSTDWQKKLDEALQRLQELQEAMDELDHKLHQAEALKGSWQPVGDLLIDSL 2969

  Fly  2751 NEQMQQLQRLRDKMTTASALLDDCNEQQSFFTANQVLVPTPCLSKLEDLNTRMKLLQIAMDERQK 2815
            .:.:.:::..:.::......::..|:....|.:..:.:.....|:|||||||.||||:::|||
Frog  2970 QDHLGKIKTFKAEIAPIKNNVNQVNDLAHQFDSTVIQLSPYNFSRLEDLNTRWKLLQVSIDER-- 3032

  Fly  2816 VLCQAGAQQTHE-NGDDGRTTSNSGTIGPLPNLGQSVKPPWERATTAANVPYYIDHERETTHWDH 2879
                  .:|.|| :.|.|.|:.:.        |..||:.|||||.:...|||||:||.:||.|||
Frog  3033 ------IRQLHEAHRDFGPTSQHF--------LSTSVQGPWERAISPNKVPYYINHETQTTCWDH 3083

  Fly  2880 PEMIELMKGLADLNEIRFSAYRTAMKLRSVQKRLALDRISMSTACESFDRHGLRAQNDKLIDIPD 2944
            |:|.||.:.|||||.:||||||||||||.:||.|.||.:.:|.|||:.|:|.|: |||:|:||..
Frog  3084 PKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLGLSAACEALDQHNLK-QNDQLMDILQ 3147

  Fly  2945 MTTVLHSLYVTIDK-----IDLTLMLDLAINWILNVYDSQRTGQIRVLSFKVGLVLLCKGHLEEK 3004
            :...|.::|..:::     :::.|.:|:.:||:|||||:.|||:|||||||.|::.|||.|||:|
Frog  3148 IINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGVISLCKAHLEDK 3212

  Fly  3005 YRYLFRLVADTDRRADQRRLGLLLHDCIQVPRQLGEVAAFGGSNIEPSVRSCLEQAGISQEAIDG 3069
            |||||:.||.:....|||||||||||.||:||||||||:|||||||||||||.:.|
Frog  3213 YRYLFKQVASSTGFCDQRRLGLLLHDAIQIPRQLGEVASFGGSNIEPSVRSCFQYA--------- 3268

  Fly  3070 NQDISIELQHFLGWLQHEPQSLVWLPVLHRLAAAEAAKHQAKCNICKEYPIVGFRYRCLKCFNFD 3134
            |....||...||.|::.||||:||||||||:||||.||||||||||||.||:|||||.||.||:|
Frog  3269 NNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYD 3333

  Fly  3135 MCQKCFFFGRNAKNHKLTHPMHEYCTTTTSTEDVRDFTRALKNKFKSRKYFKKHPRVGYLPVQSV 3199
            :||.|||.||.||.||:.:||.||||.|||.||||||.:.|||||::::||.||||:||||||:|
Frog  3334 ICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTV 3398

  Fly  3200 LEGDALE-------------SPAPSPQHTTHQLQNDMHSRLEMYASRLAQVEYGGTGSNSTPDS- 3250
            ||||.:|             :||.||| .:|   :|.|||:|.||||||::|  .|..:...||
Frog  3399 LEGDNMETPVTLINFWPVDSAPASSPQ-LSH---DDTHSRIEHYASRLAEME--NTNGSYLNDSI 3457

  Fly  3251 ------DDEHQLIAQYCQALPGTSNGSAPKSPVQVMAAMDAEQREELEAIIRDLEEENANLQAEY 3309
                  ||||.||..|||:|...|..|.|:||.|::.::::|:|.|||.|:.||||||.|||:||
Frog  3458 SPNESIDDEHLLIQHYCQSLNQESPLSQPRSPAQILISLESEERGELERILADLEEENKNLQSEY 3522

  Fly  3310 QQLCSKEQSGMPEDSNGMQ--HSSSSMTGLSGQGEQGQDMMAEAKLLRQHKGRLEARMQILEDHN 3372
            .:|  |||    .|..|:.  .|...|...|.|.::..:::||||||||||||||||||||||||
Frog  3523 DRL--KEQ----HDHKGLSPLPSPPEMMPSSPQSQRDAELIAEAKLLRQHKGRLEARMQILEDHN 3581

  Fly  3373 RQLEAQLQRLRQLLDEPNGGGSSATSSGLP-SAPGSAL----NSKPNTLQ-TRSVTASQLNTD-- 3429
            :|||:||.||||||::|.   :.|..:|.. |:|.|:|    :|:|..|: ..|.|:..:..|
Frog  3582 KQLESQLHRLRQLLEQPQ---AEAKVNGTTYSSPTSSLQRSESSQPMLLRVVGSQTSESMGEDDL 3643

  Fly  3430 -SPAK---------MNQQNGHYEHNSKGIMLPG 3452
             ||..         |.|.|..:. .::|..:||
Frog  3644 LSPPHDSSTGLEDVMEQLNNSFP-TARGRSVPG 3675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dys	NP_001036722.1	CH	13..111	CDD:278723	54/97 (56%)
		CH	129..225	CDD:278723	46/98 (47%)
		SPEC	312..525	CDD:238103	85/225 (38%)
		SbcC	<325..957	CDD:223496	172/716 (24%)
		Smc	<816..1591	CDD:224117	195/852 (23%)
		SPEC	1174..1365	CDD:238103	44/190 (23%)
		SPEC	1289..1485	CDD:295325	55/195 (28%)
		SPEC	2369..2576	CDD:238103	73/218 (33%)
		SPEC	2477..2714	CDD:238103	84/248 (34%)
		WW	2852..2882	CDD:238122	18/29 (62%)
		EF-hand_2	2883..2997	CDD:286194	59/118 (50%)
		EF-hand_3	3001..3100	CDD:286195	62/98 (63%)
		ZZ_dystrophin	3110..3158	CDD:239074	33/47 (70%)
dmd.3	XP_031752861.1	CH_DMD_rpt1	28..138	CDD:409080	59/109 (54%)
		CH_DMD_rpt2	153..262	CDD:409082	48/109 (44%)
		SPEC	357..574	CDD:238103	84/221 (38%)
		SPEC	479..684	CDD:238103	55/206 (27%)
		SPEC	739..950	CDD:238103	42/219 (19%)
		SPEC	957..1166	CDD:238103	50/212 (24%)
		SPEC	1064..1277	CDD:238103	49/235 (21%)
		Smc	1145..1974	CDD:224117	212/975 (22%)
		SPEC	1176..1383	CDD:238103	52/227 (23%)
		SPEC	2040..2213	CDD:238103	30/181 (17%)
		SPEC	2229..2429	CDD:413338	28/200 (14%)
		SPEC	2470..2678	CDD:238103	65/228 (29%)
		SPEC	2690..2931	CDD:238103	83/247 (34%)
		Spectrin	2932..3038	CDD:395348	26/113 (23%)
		WW	3057..3086	CDD:238122	18/28 (64%)
		EFh_DMD	3124..3284	CDD:320004	90/169 (53%)
		ZZ_dystrophin	3309..3357	CDD:239074	33/47 (70%)
		Smc	<3433..>3603	CDD:224117	92/180 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	248	1.000	Domainoid score	I2096
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1438	1.000	Inparanoid score	I123
OMA	1	1.010	-	-		QHG46633
OrthoDB	1	1.010	-	-		D46278at33208
OrthoFinder	1	1.000	-	-		FOG0001792
OrthoInspector	1	1.000	-	-		otm49285
Panther	1	1.100	-	-	LDO	PTHR11915
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2389
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080