DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Scsalpha2 and Suclg1

DIOPT Version :9

Sequence 1:	NP_650809.1	Gene:	Scsalpha2 / 42326	FlyBaseID:	FBgn0038708	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_063932.2	Gene:	Suclg1 / 56451	MGIID:	1927234	Length:	346	Species:	Mus musculus

Alignment Length:	326	Identity:	193/326 - (59%)
Similarity:	251/326 - (76%)	Gaps:	6/326 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SKMLLRALTPQILRRGKADYGKTVCNLK---INKATKVLVQGFTGKQATFHSEESIKYGTNIVGG 68
            :::|.|..   :|::....:|....:.|   |:|.||::.|||||||.||||:::::|||.:|||
Mouse    24 ARLLSRTF---LLQQNGIRHGSYTASRKHIYIDKNTKIICQGFTGKQGTFHSQQALEYGTKLVGG 85

  Fly    69 VNPKKGGTEHLGKPVFKSVAEAVEKAKPDATVIFIPPPSAAEGICAAIESEIGLIVAITEGIPQA 133
            ..|.|||.:|||.|||.:|.||.||....|:||::|||.||..|..||::||.|:|.|||||||.
Mouse    86 TTPGKGGQKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQ 150

  Fly   134 DMVRISQMLNCQEKSRLLGPNCPGIISPDQCKIGIMPGDIHKRGVVGIVSRSGTLTYESVHQTTN 198
            ||||:...|..|..:||:||||||:|:|.:||||||||.|||:|.:||||||||||||:|||||.
Mouse   151 DMVRVKHRLTRQGTTRLIGPNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQ 215

  Fly   199 VGLGQALCVGLGGDPFNGTSFIDALKVFLSDKEIKGIVMIGEIGGSAEEEAADFLKEKNTGCEAK 263
            |||||:||:|:||||||||.|||.|:|||:|...:||::||||||.|||.||.||||.|:|.:||
Mouse   216 VGLGQSLCIGIGGDPFNGTDFIDCLEVFLNDPATEGIILIGEIGGHAEENAAAFLKEHNSGPKAK 280

  Fly   264 PVVGFIAGQTAPPGRRMGHAGAIISGGKGAAKDKVAALEKAGVRMTANPCHLGSTLLEEMIRLKL 328
            |||.||||.|||||||||||||||:||||.||:|::||:.|||.::.:|..||:|:.:|..:.|:
Mouse   281 PVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKM 345

  Fly   329 V 329
            :
Mouse   346 L 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scsalpha2	NP_650809.1	PTZ00187	16..327	CDD:240307	190/313 (61%)
		CoA_binding	36..129	CDD:280747	52/92 (57%)
		Ligase_CoA	182..306	CDD:278948	92/123 (75%)
Suclg1	NP_063932.2	PTZ00187	19..344	CDD:240307	192/322 (60%)
		CoA_binding	53..146	CDD:280747	52/92 (57%)
		Coenzyme A binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03222	64..67		2/2 (100%)
		Coenzyme A binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03222	143..145		1/1 (100%)
		Ligase_CoA	199..324	CDD:304578	93/124 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842767
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0074
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S294
OMA	1	1.010	-	-		QHG60703
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002539
OrthoInspector	1	1.000	-	-		otm43932
orthoMCL	1	0.900	-	-		OOG6_100834
Panther	1	1.100	-	-	O	PTHR11117
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.660