DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scsalpha2 and SPAC16E8.17c

DIOPT Version :9

Sequence 1:	NP_650809.1	Gene:	Scsalpha2 / 42326	FlyBaseID:	FBgn0038708	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_594230.1	Gene:	SPAC16E8.17c / 2542341	PomBaseID:	SPAC16E8.17c	Length:	331	Species:	Schizosaccharomyces pombe

Alignment Length:	310	Identity:	192/310 - (61%)
Similarity:	240/310 - (77%)	Gaps:	1/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LRRGKADYGKTVCNLKINKATKVLVQGFTGKQATFHSEESIKYGTNIVGGVNPKKGGTEHLGKPV 83
            |:..|:.|.:|:.||.||..|||:.|||||||.|||::.::.|||.:|||.||||.||.||||||
pombe    21 LKNSKSLYEQTIPNLMINSDTKVIFQGFTGKQGTFHAQHAMDYGTKVVGGTNPKKAGTTHLGKPV 85

  Fly    84 FKSVAEAVEKAKPDATVIFIPPPSAAEGICAAIESEIGLIVAITEGIPQADMVRISQMLNCQEKS 148
            |.::.||:::.|.||:.:|:|||.||..|..||.:|:.|||||||||||.||:|:|.:|..|.||
pombe    86 FGTIEEAMKETKADASAVFVPPPLAAGAIEEAIAAEVPLIVAITEGIPQHDMLRVSDILKTQSKS 150

  Fly   149 RLLGPNCPGIISPDQCKIGIMPGDIHKRGVVGIVSRSGTLTYESVHQTTNVGLGQALCVGLGGDP 213
            ||:||||||||.|.||||||||..|||.|.:||||||||||||:|:|||...|||:|.:|:||||
pombe   151 RLVGPNCPGIIRPGQCKIGIMPSHIHKPGCIGIVSRSGTLTYEAVNQTTQTDLGQSLVIGIGGDP 215

  Fly   214 FNGTSFIDALKVFLSDKEIKGIVMIGEIGGSAEEEAADFLKEKNTG-CEAKPVVGFIAGQTAPPG 277
            |.||:||||||:||.|...:||::||||||||||:||:|::..|.. ...||||.||||.|||.|
pombe   216 FPGTNFIDALKLFLDDPNTQGIILIGEIGGSAEEDAAEFIRAANASRSTPKPVVSFIAGATAPKG 280

  Fly   278 RRMGHAGAIISGGKGAAKDKVAALEKAGVRMTANPCHLGSTLLEEMIRLK 327
            |||||||||::||||.|..|..|||.||||::.:|..|||.::||:.:||
pombe   281 RRMGHAGAIVAGGKGTAAAKFEALEAAGVRISRSPATLGSLIVEELNKLK 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scsalpha2	NP_650809.1	PTZ00187	16..327	CDD:240307	190/308 (62%)
		CoA_binding	36..129	CDD:280747	54/92 (59%)
		Ligase_CoA	182..306	CDD:278948	82/124 (66%)
SPAC16E8.17c	NP_594230.1	PTZ00187	22..330	CDD:240307	189/307 (62%)
		CoA_binding	38..131	CDD:280747	54/92 (59%)
		Ligase_CoA	184..309	CDD:278948	82/124 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	168	1.000	Domainoid score	I914
eggNOG	1	0.900	-	-		E1_COG0074
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	395	1.000	Inparanoid score	I393
OMA	1	1.010	-	-		QHG60703
OrthoFinder	1	1.000	-	-		FOG0002539
OrthoInspector	1	1.000	-	-		otm47360
orthoMCL	1	0.900	-	-		OOG6_100834
Panther	1	1.100	-	-	O	PTHR11117
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1662
TreeFam	1	0.960	-	-
	12	11.830