DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5316 and Aptx

DIOPT Version :9

Sequence 1:	NP_650805.1	Gene:	CG5316 / 42322	FlyBaseID:	FBgn0038704	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_017448660.1	Gene:	Aptx / 259271	RGDID:	628740	Length:	343	Species:	Rattus norvegicus

Alignment Length:	178	Identity:	72/178 - (40%)
Similarity:	104/178 - (58%)	Gaps:	9/178 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 WSSALIKDISKPENLIISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLNRSHLSLLEELHLLA 67
            ||..|...:..|:..:...:..|||.||:|||:||:||||.|.|.|:..:...||.||:.:|.:.
  Rat   168 WSQGLKISMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVG 232

  Fly    68 RNVV-EVKGVRWQDFNVGFHAEPSMQRLHLHVISKDFVSTSLKTKKHWNSFNTELFVPYTKLYAQ 131
            ..|: :..|.....|.:|:||.|||..:||||||:||.|..||.||||||||||.|:....:...
  Rat   233 EKVIADFTGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKM 297

  Fly   132 LEKENSISRLPKSLKD---ELLAKPLICNQCEFVARNLPSLKGHLVGH 176
            :::...:     ::||   |||..||.|::|:.:..::|.||.||..|
  Rat   298 VQEAGRV-----TVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKH 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5316	NP_650805.1	DcpS_C	8..100	CDD:288796	36/92 (39%)
		zf-C2HE	119..179	CDD:292895	18/61 (30%)
		DcpS_C	235..326	CDD:288796
		zf-C2HE	345..405	CDD:292895
Aptx	XP_017448660.1	FHA	<38..112	CDD:238017
		aprataxin_related	165..266	CDD:238609	39/97 (40%)
		zf-C2HE	285..341	CDD:292895	18/61 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351312
Domainoid	1	1.000	91	1.000	Domainoid score	I7573
eggNOG	1	0.900	-	-		E1_KOG0562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1290702at2759
OrthoFinder	1	1.000	-	-		FOG0003607
OrthoInspector	1	1.000	-	-		oto97016
orthoMCL	1	0.900	-	-		OOG6_103324
Panther	1	1.100	-	-	LDO	PTHR12486
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4024
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.750