Protein Alignment CG18493 and K12H4.7

DIOPT Version :10

• Sequence 1: NP_650803.1
• Gene: CG18493 / 42319
• FlyBaseID: FBgn0038701
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_498758.2
• Gene: K12H4.7 / 176136
• WormBaseID: WBGene00019682
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 154/540 - (28%)
• Similarity: 242/540 - (44%)
• Gaps: 98/540 - (18%)

  Fly     1 MAALRLVCLFVVLAIGLVQSLDIPKIKDVPLLVKTLKNLNRGPPHQVVTKRA------------N 53
            :|.|...|:       |.|.|..|..:.     :..:|:.||.|...:.|..            |
 Worm     5 LAVLLAACV-------LTQVLSAPSNEQ-----RVRRNMIRGRPRGGMKKTPPMSSVSHMINFDN 57

  Fly    54 VQEKWITQKLDNFNASNTQTYQMRYLLNDEFQTEGSPIFIYLGGE------W------EIEESMV 106
            |.....||.||:|::|..:|:|.||..|:::...|.|.|:.||||      |      ||.....
 Worm    58 VVSSTFTQTLDHFDSSVGKTFQQRYYHNNQWYKAGGPAFLMLGGEGPESSYWVSYPGLEITNLAA 122

  Fly   107 SAGHW-YDMAQEHNGVLVYTEHRYYGQSIPTSTMSTEDLKYLDVKQALADVAVFIETFKAENPQL 170
            ..|.| :|:           |||:||::.|||.||..:||||...||:.|.|.||:...|:.|||
 Worm   123 KQGAWVFDI-----------EHRFYGETHPTSDMSVPNLKYLSSAQAIEDAAAFIKAMTAKFPQL 176

  Fly   171 ANSKVILAGGSYSATMVVWFKRLYPDLIVGGWASSAPILAKVDFTEYKEVVGQAFLQLGGQKCYD 235
            ||:|.:..|||||..:..|.:..:|:|:.....||.|:.|:|||.||.||| |..:.....:|..
 Worm   177 ANAKWVTFGGSYSGALAAWTRAKHPELVYAAVGSSGPVQAEVDFKEYLEVV-QNSITRNSTECAA 240

  Fly   236 RIENGIAELESMFANKRG-AEARAMLRLCN--SFDDQNDLDLW-TLFSSISNIFAGVAQYQGTGD 296
            .:..|...:.|:.....| .:.:....||.  ..||::....| |::|.    :..|.||.|...
 Worm   241 SVTQGFNLVASLLQTSDGRKQLKTAFHLCQDIQMDDKSLKYFWETVYSP----YMEVVQYSGDAA 301

  Fly   297 IEY---------YCDY-----------LLSFNDDATAIANFVYWAWGMGNCIDARYEGSVEYY-- 339
            ..:         .|.|           |...||....::       |...|.|..|.|.:.:.
 Worm   302 GSFATQLTISHAICRYHINTKSTPLQKLKQVNDYFNQVS-------GYFGCNDIDYNGFISFMKD 359

  Fly   340 -LWGVDHFDASRPWYYQTCNEYGWYQSSGSRNQP--FG--TKFPATLYINLCGDVFSSQYGNEQI 399
             .:|....|  |.|.:|||.|:|:|||:.|....  ||  :..||..||:.|..::.:.|.::::
 Worm   360 ETFGEAQSD--RAWVWQTCTEFGYYQSTSSATAGPWFGGVSNLPAQYYIDECTAIYGAAYNSQEV 422

  Fly   400 NNNAASTNEYFGGMEP-GVDNIYMTHGELDPWNPMGHGVEQGA----TVIANASHCSDFGSIKST 459
            ..:...||:|:||.:. ..|.|.:.:|::|||:.:|......:    .||...:||:|.....|.
 Worm   423 QTSVDYTNQYYGGRDNLNTDRILLPNGDIDPWHALGKLTSSNSNIVPVVINGTAHCADMYGASSL 487

  Fly   460 DSDEMRASKEKLAELVRQWL 479
            ||..:..:::::::::..||
 Worm   488 DSMYLTNARQRISDVLDGWL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18493	NP_650803.1	alpha/beta hydrolases	61..471	CDD:473884	137/458 (30%)
K12H4.7	NP_498758.2	Peptidase_S28	65..499	CDD:310284	137/458 (30%)