Protein Alignment Ino80 and PIE1

DIOPT Version :10

• Sequence 1: NP_732413.1
• Gene: Ino80 / 42314
• FlyBaseID: FBgn0289122
• Length: 1638
• Species: Drosophila melanogaster
• Sequence 2: NP_187887.3
• Gene: PIE1 / 820463
• AraportID: AT3G12810
• Length: 2055
• Species: Arabidopsis thaliana
• Alignment Length: 1550
• Identity: 416/1550 - (26%)
• Similarity: 658/1550 - (42%)
• Gaps: 373/1550 - (24%)

  Fly    82 SKRKSRLLASKEERQS-------VKAQLYNFNDLTSDREWLYDL-----------LLSDTESDDP 128
            :||:..|.|.||.|:.       ::...:...|..|:|:|....           :|.....::.
plant    29 AKRQKTLEAPKEPRRPKTHWDHVLEEMAWLSKDFESERKWKLAQAKKVALRASKGMLDQASREER 93

  Fly   129 TITEDEYVQQLLREHVREQRQRKNYYKKAANAQYAYYGSGLLSNHDIFAERQLATAGVRKRRRRT 193
            .:.|:|  |:|.:..:...:..|.::.|.  .:...|...|:.|.             :|::...
plant    94 KLKEEE--QRLRKVALNISKDMKKFWMKV--EKLVLYKHQLVRNE-------------KKKKAMD 141

  Fly   194 KQ-EILMAR-------LAEAQAGPKPPKQRRRGRKKR----DNMGSPESGEVPPSELGKYTFGDT 246
            || |.|:.:       |||...  :|.||.:....|.    ::....|..|..|.|:
plant   142 KQLEFLLGQTERYSTMLAENLV--EPYKQGQNTPSKPLLTIESKSDEERAEQIPPEI-------- 196

  Fly   247 LPNNEDDDEDGG-EVDYKRELASLALDYPEEEEIEEEVDVEGGTEGQVTKVRRKRKNPAALAARR 310
              |:....|.|. |:|...:|.|       |:|.|::.|.....|...||..|:.:..|......
plant   197 --NSSAGLESGSPELDEDYDLKS-------EDETEDDEDTIEEDEKHFTKRERQEELEALQNEVD 252

  Fly   311 RRIWQIMSKKESGRLQR----IKSNNHKEMLANCKRVAG--------MCAKVVRQRA--INSQRI 361
            ..:.:::.:..|||:.|    :|..| ::.|.:..||..        ..|.|.:...  .|:...
plant   253 LPVEELLRRYTSGRVSRETSPVKDEN-EDNLTSVSRVTSPVKDENQDNLASVGQDHGEDKNNLAA 316

  Fly   362 MKETVWR-AKRLTREMLAYWKRYERVERDQRRKQEREAEEQRKQDVELIEVKRQQRKLNFLITQT 425
            .:||... :.|.:.:...:....|....|........:.:.||:| ...:...:|..::|:
plant   317 SEETEGNPSVRRSNDSYGHLAISETHSHDLEPGMTTASVKSRKED-HTYDFNDEQEDVDFV---- 376

  Fly   426 ELYAHFMSKKLGQGSEEDQLRILSQLDEETNA---RLAAQDDYDAGEMKLLAQENAEAAMQ---- 483
                      |..|.|:|        ||.|.|   .||..|:.|..|...|.|:.:|..::
plant   377 ----------LANGEEKD--------DEATLAVEEELAKADNEDHVEEIALLQKESEMPIEVLLA 423

  Fly   484 --------RDLDKTRAFDVFAKKKEK---EEEEQAQESVED---------IKPEPRPEM------ 522
                    :|:.:..:...||..::.   .:|.:.|..::|         :.|||..|.
plant   424 RYKEDFGGKDISEDESESSFAVSEDSIVDSDENRQQADLDDDNVDLTECKLDPEPCSENVEGTFH 488

  Fly   523 -------KDLPQ----------------------------PKMFKGTLKGYQIKGMTWLANIYDQ 552
                   ||...                            |.:.|.:|:.||..|:.||..:|::
plant   489 EVAEDNDKDSSDKIADAAAAARSAQPTGFTYSTTKVRTKLPFLLKHSLREYQHIGLDWLVTMYEK 553

  Fly   553 GISGILADEMGLGKTVQSIAFLCHIAEHYGVWGPFLVISPASTLHNWQQEMSRFVPDFKVVPYWG 617
            .::||||||||||||:.:||.|.|:|...|:|||.|::.|.|.:.||:.|..::.|.||::.|:|
plant   554 KLNGILADEMGLGKTIMTIALLAHLACDKGIWGPHLIVVPTSVMLNWETEFLKWCPAFKILTYFG 618

  Fly   618 SPAERKILRQFWDQKHLHTRDASFHVVITSYQLVVSDYKYFNRIKWQYMVLDEAQAIKSAASQRW 682
            |..|||:.||.|.:.:      ||||.||:|:||:.|.|.|.|.||:|::||||..||:..||||
plant   619 SAKERKLKRQGWMKLN------SFHVCITTYRLVIQDSKMFKRKKWKYLILDEAHLIKNWKSQRW 677

  Fly   683 KLLLGFSCRNRLLLSGTPIQNSMAELWALLHFIMPTLFDSHDEFNEWFSKDIESHAENKTGIDEK 747
            :.||.|:.:.|:||:|||:||.:.|||:|:||:||.:|.||.||.:||...|....|.:..|:::
plant   678 QTLLNFNSKRRILLTGTPLQNDLMELWSLMHFLMPHVFQSHQEFKDWFCNPIAGMVEGQEKINKE 742

  Fly   748 QISRLHMILKPFMLRRIKKDVENELSDKIEIMVYCPLTIRQKLLYRALKQKIRIEDLLHLTSGST 812
            .|.|||.:|:||:|||:|:|||.:|..|.|.:::|.|:.||:.||         ||.:..|. :.
plant   743 VIDRLHNVLRPFLLRRLKRDVEKQLPSKHEHVIFCRLSKRQRNLY---------EDFIASTE-TQ 797

  Fly   813 TTSSSSSASNLMNLVMQFRKVCNHPELFERRDARSPFFMRCAEYTIPRLIHEEGLIHRMLPSRKH 877
            .|.:|.|...:::::||.|||||||:|||.|...|.|.|...:..:...|
plant   798 ATLTSGSFFGMISIIMQLRKVCNHPDLFEGRPIVSSFDMAGIDVQLSSTI--------------- 847

  Fly   878 LLYNRFNIFKSEYIQRSLFEDVNVNSC-FGFTRLCDLSV----GDMVEV--TLNGLIDFLLHYRR 935
                      ...:..|.|..|::.:. |.||.| |.|:    ||.::.  |.:.||...::.:.
plant   848 ----------CSLLLESPFSKVDLEALGFLFTHL-DFSMTSWEGDEIKAISTPSELIKQRVNLKD 901

  Fly   936 VLEKYPLLAYRRFWWKKQPDSRYQLLEPMLENKLALDYMPPNSVLKNFIFTAMTANESSVYAFGD 1000
            .||..||          .|.:|
plant   902 DLEAIPL----------SPKNR------------------------------------------- 913

  Fly  1001 YFTYNMQETIEHRVIRSKILKKKTSLIEEMEDVSKQKLEIESVEVQTKSNAKSDVKVTTLLLLPE 1065
               .|:|.|.....||..:.:::   |:|.:|.:.......|:..|.|....:.::  |||.:
plant   914 ---KNLQGTNIFEEIRKAVFEER---IQESKDRAAAIAWWNSLRCQRKPTYSTSLR--TLLTI-- 968

  Fly  1066 FPHRPRKPRKYVCEPLSMPRILYDL--------GQKVQAVHRYLYCDSRS-----AAWSQIRHNQ 1117
              ..|....|..|.......||.|:        .:.::.|..:.:....:     ..|
plant   969 --KGPLDDLKANCSSYMYSSILADIVLSPIERFQKMIELVEAFTFAIPAARVPSPTCW------- 1024

  Fly  1118 CENSQG------------RELVSSGLALCKPHGGWSSIVVPDKETLITDAGKLFVLDNLLTRLKA 1170
            |..|..            .:|:|..|:..:|......:..||:..:..|.|||..|..||.:||.
plant  1025 CSKSDSPVFLSPSYKEKVTDLLSPLLSPIRPAIVRRQVYFPDRRLIQFDCGKLQELAMLLRKLKF 1089

  Fly  1171 NGHRVLIYSQMTKMIDLLEEYMWHRKHRYMRLDGSSKISARRDMVADFQTRADIFVFLLSTRAGG 1235
            .|||.||::|||||:|:||.::....:.|||||||:....|:.::..|.|...||:|:||||:||
plant  1090 GGHRALIFTQMTKMLDVLEAFINLYGYTYMRLDGSTPPEERQTLMQRFNTNPKIFLFILSTRSGG 1154

  Fly  1236 LGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAREKSEIQ 1300
            :||||..|||||||||||||.:||||.||.||:|||::|.:||||.:.||||.||::|.:|..:.
plant  1155 VGINLVGADTVIFYDSDWNPAMDQQAQDRCHRIGQTREVHIYRLISESTIEENILKKANQKRVLD 1219

  Fly  1301 RMVISGGNFKPDTLKPKEVVSLLLDDEEIEMKYRQEAKLQSSSPIP---AATQSERKRRHPQKDV 1362
            .:||..|.:..:..|..:.:.|....:.:..|..:|......:.||   |..::..|:...:.|.
plant  1220 NLVIQNGEYNTEFFKKLDPMELFSGHKALTTKDEKETSKHCGADIPLSNADVEAALKQAEDEADY 1284

  Fly  1363 NMGGTTIAATSATQN----------PDDDVPSCSSAAKRIKLETEEDF-----IDVGITSSASSV 1412
             |....:....|..|          |:||           :|..|:|.     .|.|:.::.
plant  1285 -MALKRVEQEEAVDNQEFTEEPVERPEDD-----------ELVNEDDIKADEPADQGLVAAG--- 1334

  Fly  1413 GTDSNHPTLSQETYVPGATCVQQTEIDSENEALVVDGDSPTMLGQNESMNFLDDL 1467
                           |....:.....|..:|..|:     |...|.:..:.|||:
plant  1335 ---------------PAKEEMSLLHSDIRDERAVI-----TTSSQEDDTDVLDDV 1369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ino80	NP_732413.1	HepA	364..>855	CDD:440319	186/559 (33%)
		DEXQc_INO80	535..763	CDD:350760	109/227 (48%)
		SF2_C_SNF	1146..1280	CDD:350180	74/133 (56%)
		PHA03247	<1535..1637	CDD:223021
PIE1	NP_187887.3	HSA	36..106	CDD:214727	13/71 (18%)
		DEXQc_SRCAP	536..758	CDD:350761	109/227 (48%)
		DISARM_DrmD_b	554..1488	CDD:468472	304/964 (32%)
		SF2_C_SNF	1064..1199	CDD:350180	74/134 (55%)