|
Fly 208 GPKPPKQR--RRGRKKRDNMGSPESGEVPPSELGKYTFGDTLPNNEDDDEDGGEVDYKRELASLA 270
||.|.:.. .|.....:...||.:...|...:.......:...|....:||
Mouse 677 GPSPARSSPVNRPSSATNKALSPITSRSPGVAVSAPPKPQSPAQNAASSQDG------------- 728
Fly 271 LDYPEEEEIEEEVDVEGGTEGQVTKVRRK-----RKNPAAL-AARRRRIWQIMSKKESGRLQRIK 329
.::::.|::.:|.....::..:|:: |:.|... |.|.:..|..:.:: :|.:.
Mouse 729 ----SQDKLAEQITLENQIHQRIADLRKEGLWSLRRLPKLQEAPRPKSHWDYLLEE----MQWMA 785
Fly 330 SNNHKE---MLANCKRVAGMCAKVVRQRAINSQRIMKETVWRAKRL----TREMLAYWKRYERVE 387
::..:| .||..|::....|:...::.:..:|..||...|.:|: .||:..:|...|:|
Mouse 786 TDFAQERRWKLAAAKKLVRTVARHHEEKKLREERGKKEEQSRLRRIAATTAREIEYFWSNIEQV- 849
Fly 388 RDQRRKQEREAEEQRKQDVELIEVKR--QQRKLNFLITQTELYAHFM-------SKKLGQGSEED 443
...|.:.|.||:||:.:.|.:|.| ::.:|....|..| |.: .:|......:|
Mouse 850 --VEIKLQVELEEKRKKALNLQKVSRRGKESRLKGFDTSPE---HSLDLGISGRKRKASTSLTDD 909
Fly 444 QLRILSQLDEETNARLAAQDDYDAGEMKLLAQENAEAAMQRDLDKTRAFD-------VFAKKKEK 501
::....:..||..|.....|.:. |:..||:| ||..: :|..:.:: .:.:.:..
Mouse 910 EVEDEEETIEEEEAHEGLVDHHT--ELTNLAKE-AELPL---IDLMKLYEGAFLPNFQWPQPEPD 968
Fly 502 EEEEQAQESVEDIKPEPRPEMKD---------------------------------------LPQ 527
.||...:|.|||. |..|...:| ||:
Mouse 969 HEESSGEEDVEDC-PSDRESRRDSVLIDSLFIMDQFKAAERMSIGKSNTKDITEVTAVAEAILPK 1032
Fly 528 -------------PKMFKGTLKGYQIKGMTWLANIYDQGISGILADEMGLGKTVQSIAFLCHIAE 579
|.:..|.|:.||..|:.|||.:|.:.::||||||.|||||||.|||..|:|.
Mouse 1033 GSARVTTAVKFSAPSLLYGALRDYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLAC 1097
Fly 580 HYGVWGPFLVISPASTLHNWQQEMSRFVPDFKVVPYWGSPAERKILRQFWDQKHLHTRDASFHVV 644
:.|.|||.||:..:..:..|:.|:.|:.|..|.:.|.||..|.|..||.| |...:||:.
Mouse 1098 NEGNWGPHLVVMRSCNILKWELELKRWCPGLKTLSYVGSHRELKAKRQEW------TEPNNFHIC 1156
Fly 645 ITSYQLVVSDYKYFNRIKWQYMVLDEAQAIKSAASQRWKLLLGFSCRNRLLLSGTPIQNSMAELW 709
||||:.....|..|:|:.|:.:|:||.|.:|....:.|:.:.....:.||||...|:.|:..|||
Mouse 1157 ITSYKQFFRGYTAFSRVHWKCLVVDEMQRVKGMTERHWEAIFKLQSQQRLLLIDVPLHNTFLELW 1221
Fly 710 ALLHFIMPTLFDSHDEFNEWFSKDIESHAENKTGIDEKQISRLHMILKPFMLRRIKKDVENELSD 774
.::||::|.: ...:.|..:::..|.......|.:.|||.:.:||:|||.|:|||.:|:.
Mouse 1222 TMVHFLIPGI------SRPYLSFPLKAPNEENQDYYHKMVIRLHRVTQPFILRRTKRDVEKQLTR 1280
Fly 775 KIEIMVYCPLTIRQKLLYRALKQKIRIEDLLHLTSGSTTTSSSSSASNLMNLVMQFRKVCNHPEL 839
|.|.::.|.|:.|||.||..:..:.|.::.| .|....::::::.:.:::||||.|
Mouse 1281 KYEHVLKCRLSSRQKALYEDVILQPRTQEAL----------KSGHFVSVLSVLTRLQRICNHPGL 1335
Fly 840 FERRDARSPFFMRCAEY----TIPRLIHEE-------------GLIHRMLPSRKHLLYNRFNIFK 887
.|.|...|.|.....:| .|.|::..| ||.:::......||..:
Mouse 1336 VEPRVPGSSFAAGSLQYKSASLILRVLEREFWKETDLSIFDLIGLENKITRHEAELLCKK----- 1395
Fly 888 SEYIQRSLFEDV----------------------------------------------NVNSCFG 906
.:.|.|.|:| |.|:...
Mouse 1396 --KVTRKLMEEVFASPPPSARPAAVKLKASRLFQPVQYGQKPEGRTVAFPSTHPPRMANTNTSTA 1458
Fly 907 --------------FTRLCDLSVGDMVEVTLNGLIDFLLHYRRVLEKYPLLAYRRFWWKKQPDSR 957
|:...|...|::|::.....| ..|.||
Mouse 1459 TPQGQVRGRPPIATFSANPDTKGGEVVKIAQLASI------------------------AGPQSR 1499
Fly 958 YQLLEPMLENKLALDYMPPNSVLKNFIFTAMTANE---------SSVYAFGDYFTYN----MQET 1009
:.:| |..:.|.:......|.:.....:||.: ..|.|.|..:... :.:|
Mouse 1500 --VAQP--ETPVTLQFQGNKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQT 1560
Fly 1010 IE-----HRVIRSK--------------------------------ILKKKTS-----LIEEMED 1032
:. |..:.|| :..|..| ..||...
Mouse 1561 VSQAGAVHSTLGSKPPTSGPSPAPLTPQVGVPGRVAVSAMAVGEPGLASKPASPAAGPTQEEKSR 1625
Fly 1033 VSKQKL-EIESVEVQTKSNAKSDVKVTTLLLLPEFPHRPRKPRKYVCEPLSM-----PR-ILYDL 1090
:.|::| :|..:..:..|.| .|....||.:...|.|.::| :|..|.. |: :.||:
Mouse 1626 LLKERLDQIHFINERRCSQA--PVYGRDLLRICSLPGRRKRP---LCWSLDSNFGKGPKGVNYDM 1685
Fly 1091 G--------------QKVQAVHRYLYC---------------------DSRSAAWSQI--RHNQC 1118
. :.:|.|...:.| .||..|..|. .|...
Mouse 1686 SLSKSEGDLILTLSQESLQDVLGRVACVIPPVVATPPSLWVARPPSLYSSRLRALRQCLREHTGP 1750
Fly 1119 ENSQGRELVSSGLALCKPHGGWSSIVVPDKETLITDAGKLFVLDNLLTRLKANGHRVLIYSQMTK 1183
.:.|.::|.: ..|:..|:...:..|:|||..|..||.:||:.|.||||.|||..
Mouse 1751 YHRQLQQLTA-----------LRSLQFPELRLVQFDSGKLEALAILLQKLKSEGRRVLILSQMVL 1804
Fly 1184 MIDLLEEYMWHRKHRYMRLDGSSKISARRDMVADFQTRADIFVFLLSTRAGGLGINLTAADTVIF 1248
|:|:||.::......|:|:|.::....|::::..|.....||..||||.:...||||..||||:|
Mouse 1805 MLDILEMFLNFHYLTYVRIDENANSEQRQELMRSFNRDRRIFCALLSTHSRATGINLVEADTVVF 1869
Fly 1249 YDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAREKSEIQRMVISGGNFKPDT 1313
||:|.||.:|.:|.:...|:|:.|.:.:|||:...:|||::|:.. .|..|:.:...|.::....
Mouse 1870 YDNDLNPVMDAKAQEWCDRIGRCKDIHIYRLVSGNSIEEKLLKNG-TKDLIREVAAQGNDYSMAF 1933
Fly 1314 LKPKEVVSLL-----LDDEEIEMKYRQEAKLQS------------SSPIPAATQS----ERKRRH 1357
|..:.:..|. :||....:|..:...|.. :.|...|.:| |...:.
Mouse 1934 LTQRTIQELFEVYSPMDDTGFPVKAEEFVVLSQEPSVSETIAPKIARPFIEALKSIECLEEDAQR 1998
Fly 1358 PQKDVNMGGTTIAATSATQNPD-DDVPSCSSAAKRIKLETEEDFID--VGITSSASSVGTDSNHP 1419
..::...|.:::|.:|.:.... |:.|| :||...||:: ..|...|.:. .:..|.
Mouse 1999 STEEAVPGSSSVAVSSDSDGSRYDEEPS--------QLEELADFMEQLTPIEKYALNY-LELFHT 2054
Fly 1420 TLSQETYVPGATCVQQTEIDSE--NEALVVDGDSPTMLGQNE------------SMNFL-DDLSG 1469
|..||........|..:..|.| |...:.:.::...|.|.| :|.:: :|..|
Mouse 2055 TTEQEKERISEDLVMASMKDWETRNARALQEREARLQLEQEEAELLTYTREDAYTMEYVYEDADG 2119
Fly 1470 ---ISPMRRRHHPRGTRRGRPRGSTRRGGGHGSIPRVLTPTQAATPAVPATASQAAAAGTGAAAG 1531
:.|: .|| |..|...:............
Mouse 2120 QTEVMPL------------------------------WTP-----PTPPQDDNDIYIDSVMCLMY 2149
Fly 1532 TSSPLPQQEVSGGGDNAGVPLH----EEEYRTSPSGQSPGVSCKRGPGR----PRSKTATPISRG 1588
.::|:|:.::. |:: .:.::|.|| :.|...|:..|. |||. ..|.
Mouse 2150 ETTPIPEAKLP--------PVYVRKERKRHKTDPS--AAGRKKKQRHGEAVVPPRSL----FDRA 2200
Fly 1589 TRGAPRARR------------PMGPLLVPLGRSPDDTPPSSSPATSRAPSPLSGSHGAV 1635
|.|..:.|| ...|...|| |.....|..||.. :|..|.|...|:
Mouse 2201 TPGMLKIRREGKEQKKNLLLKQQTPFAKPL---PTYVKSSGEPAQD-SPDWLIGEDWAL 2255
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