Protein Alignment Ino80 and XNP

DIOPT Version :9

• Sequence 1: NP_732413.1
• Gene: Ino80 / 42314
• FlyBaseID: FBgn0086613
• Length: 1638
• Species: Drosophila melanogaster
• Sequence 2: NP_651398.1
• Gene: XNP / 43080
• FlyBaseID: FBgn0039338
• Length: 1311
• Species: Drosophila melanogaster
• Alignment Length: 1641
• Identity: 310/1641 - (18%)
• Similarity: 562/1641 - (34%)
• Gaps: 551/1641 - (33%)

  Fly    67 SDDSSTVGVVRMKQSSKRKSRLLASKEERQSVKAQLYNFNDLTSDREWLYDLLLSDTESDDPTIT 131
            :|||::..|.|.:.:::.||                                 .|::||..|
  Fly    19 TDDSNSSSVSRRESATESKS---------------------------------ASESESSPP--- 47

  Fly   132 EDEYVQQLLREHVREQRQRKNYYKKAANAQYAYYGSGLLSNHDIFAERQLATAGVRKRRRRTKQE 196
                     |.:.::.|..|| .|.:..|..:       |:.|  :::.:|.:......:....:
  Fly    48 ---------RSNTKQSRTHKN-VKASGKATVS-------SSSD--SDQAVANSSANDEEKEPVCK 93

  Fly   197 ILMARLAEAQAGPKPPKQRRRGRKKRDNMGSPESGEVPPSELGKYTFGDTLPNNED----DDEDG 257
            |.:..|.:..|.||..::..||.::: |:...:|.:..|.:..|.........|::    :..|.
  Fly    94 IRIVPLEKLLASPKTKERPSRGSQQK-NVTINDSSDEEPLKGSKLVLPARKSRNKNASIIELSDS 157

  Fly   258 GEVDYKRELASLALDYPEE-EEIEEEVDVEGGTEGQVTKVRRKRKNPAALAARRRRIWQ-----I 316
            .|||.:.|...:|:..|:| ::.:.|.:....::..:.|.::.:|.....:||..|...     .
  Fly   158 EEVDEEEESLLVAIPLPKEAQQTKPEKNSSKASKESIEKRQKAQKEATTSSARAIRSVNGTRRGS 222

  Fly   317 MSKKESGRLQRIKSNN---HKEMLANCKRV--------------------AGMCAKVVRQRAINS 358
            :|.:.|.|....::.:   .|..:...|||                    |...:|..|||...|
  Fly   223 LSSERSSRASSSRAESPPRPKRCVVRLKRVSLPKTKPAQKPKKMSSDSEEAATTSKKSRQRRSKS 287

  Fly   359 QRIMKETVWRAKRLTREMLAYWKRYERVERDQRRKQEREAEEQRKQDVELIEVKRQQRKLNFLIT 423
            :. ..::.:.|.....|           |.::|:....|.|.....|.|::..::::||
  Fly   288 ES-EADSDYEAPAAEEE-----------EEEERKSSGDEEEAANSSDSEVMPQRKRRRK------ 334

  Fly   424 QTELYAHFMSKKLGQGS-----EEDQLRILSQLDEETNARLAAQDDYDAGEMKLLAQENAEAAMQ 483
                     ..:..:||     ||.|.:...:..::|:   :.:.|.|..:.|   |:|....:
  Fly   335 ---------KSESDKGSSDFEPEEKQKKKGRKRIKKTS---SGESDGDGDDDK---QKNKRKHI- 383

  Fly   484 RDLDKTRAFDVFAKKKEKEEEEQAQ----------------ESVE------DIKPEPRPEMKDLP 526
            |.:.||:..|:..|:..|||:::.:                ||||      |...|.:..:..:.
  Fly   384 RKIIKTKDLDLTTKEAAKEEDDRRKRIEDRQKLYNRIFVKSESVEINELVLDFDEESKKALLQVD 448

  Fly   527 QPKMFKGTLKGYQIKGM--TW------LANIYDQGISG-ILADEMGLGKTVQSIAFLCHI----A 578
            :..:.|  ||.:|:.|:  .|      |....::..|| |||..||||||:| :..|.|.    .
  Fly   449 KGLLKK--LKPHQVAGVKFMWDACFETLKESQEKPGSGCILAHCMGLGKTLQ-VVTLSHTLLVNT 510

  Fly   579 EHYGVWGPFLVISPASTLHNWQQEMSRF--------VPDFKVVPYWGSPAERKILRQFWDQKHLH 635
            ...|| ...|:|||.||::||.:|.:.:        :..:.:..|...|.....|.:::::.
  Fly   511 RRTGV-DRVLIISPLSTVNNWAREFTSWMKFANRNDIEVYDISRYKDKPTRIFKLNEWFNEG--- 571

  Fly   636 TRDASFHVVITSYQL--VVSDYKYFNRIKWQ--------------YMVLDEAQAIKSAASQRWKL 684
                  .|.|..|.:  ::::.|.....|.|              .:|.||...:|:..:...|.
  Fly   572 ------GVCILGYDMYRILANEKAKGLRKKQREQLMQALVDPGPDLVVCDEGHLLKNEKTSISKA 630

  Fly   685 LLGFSCRNRLLLSGTPIQNSMAELWALLHFIMPTLFDSHDEFNEWFSKDIESHAENKTGIDEKQI 749
            :.....:.|::|:|||:||::.|.:.::.|:.|.|..::.|:
  Fly   631 VTRMRTKRRIVLTGTPLQNNLREYYCMIQFVKPNLLGTYKEY----------------------- 672

  Fly   750 SRLHMILKPFMLRRIKKDVENELSDKIEIMVYCPLTIRQKLLYRALKQKIRIEDLLHLTSGSTTT 814
              ::..:.|                                                :|:|..|.
  Fly   673 --MNRFVNP------------------------------------------------ITNGQYTD 687

  Fly   815 SSSSSASNLMNLVMQFRKVCNHPELFERRDARSPFFMRCAEYTIPRLIHEEGLIHRMLPSRKHLL 879
            |:                         .||.                        |::..|.|:|
  Fly   688 ST-------------------------ERDL------------------------RLMKHRSHIL 703

  Fly   880 YNRFNIFKSEYIQRSLFEDVNVNSCFGFTRLCDLSVGDMVEVTLNGLIDFLLHYRRVLEKYPLLA 944
            :.                                        .|.|.|.
  Fly   704 HK----------------------------------------LLEGCIQ---------------- 712

  Fly   945 YRRFWWKKQPDSRYQLLEPMLENKLALDYMPPNSVLKNFIFTAMTANESSVYAFGDYFTYNMQET 1009
             ||         .|.:|.|         |:||..  :..::|.::..:..:|  |.|.|.:.:::
  Fly   713 -RR---------DYSVLAP---------YLPPKH--EYVVYTTLSELQQKLY--GYYMTTHREQS 754

  Fly  1010 IEHRVIRSKILKKKTSLIEEMEDVSK-----QKLEIESVEVQTK---SNAKSDVKVTTLLLLPEF 1066
                  ...::.|...|.::.:|:.:     ..|.:.|..|..|   ||..||::
  Fly   755 ------GGDVVGKGARLFQDFQDLRRIWTHPMNLRVNSDNVIAKRLLSNDDSDME---------- 803

  Fly  1067 PHRPRKPRKYVCEPLSMPRILYDLGQKVQAVHRYLYCDSRSAAWSQIRHNQCEN-SQGRELVSSG 1130
                    .::|:.........:.....:...........:|:..:::..:..| :.|.....|.
  Fly   804 --------GFICDETDEDEAASNSSDSCETFKSDASMSGLAASSGKVKKRKTRNGNAGGGDSDSD 860

  Fly  1131 LALCKPHGGWSSI-----------VVPDKE-TLITDAGKLFVLDNLLTRLKANGHRVLIYSQMTK 1183
            |.:....||.||:           .|.::| ..:..:.||.:|..||.:.:|.|.::|::||..:
  Fly   861 LEMLGGLGGGSSVQKDDPSEWWKPFVEERELNNVHHSPKLLILLRLLQQCEAIGDKLLVFSQSLQ 925

  Fly  1184 MIDLLEEYM----------------------WHRKHRYMRLDGSSKISARRDMVADFQ--TRADI 1224
            .:|::|.::                      |.....|.|||||..:..|..|...|.  |....
  Fly   926 SLDVIEHFLSLVDSNTKNYEFEGDVGDFKGCWTSGKDYFRLDGSCSVEQREAMCKQFNNITNLRA 990

  Fly  1225 FVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERI 1289
            .:||:|||||||||||.||:.|:.:|..|||:.|.|::.|.:|.||.|...:||||..||:|:::
  Fly   991 RLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDTQSIFRVYRFGQIKPCYIYRLIAMGTMEQKV 1055

  Fly  1290 LQR-----------------AREKSEIQRMVISGGNFKPDT-----LKPKE--VVSLLLDDEEIE 1330
            .:|                 :|..::...|.:.....||.|     :.||:  ...:|.:.|::.
  Fly  1056 YERQVAKQATAKRVIDEQQISRHYNQTDLMELYSYELKPSTEREMPILPKDRLFAEILTEHEKLI 1120

  Fly  1331 MKYRQEAKLQSSSPIPAATQSERK----------------RRHPQKDVNMGGTTI------AATS 1373
            .||.:...|.........|:.|||                .::...|.|..|..:      |:.|
  Fly  1121 FKYHEHDSLLEQEEHENLTEEERKSAWAEYEAEKTRTVQASQYMSYDRNAFGNQVMGQFGNASGS 1185

  Fly  1374 ATQNPDDDVPSCSSAAKRIKLETEEDFIDVGITSSASSVGTDSNHPTLSQE---TYVPGATCVQQ 1435
            .|.|            |.....::       |.....::....:|..|:|.   ..||  |.:||
  Fly  1186 VTSN------------KIFGFRSD-------ILLQLLNMKISKDHQELNQNQVIQLVP--TYLQQ 1229

  Fly  1436 TEIDSENEALVVDGDSPTMLGQNESMNFLDDLSGISPMRRRHHPRGTRRGRPRGSTRRGGGHGSI 1500
            ...:..|      || |||  ..:.:|...::  :.|.....:|.......|..:....|..|..
  Fly  1230 LYNEMNN------GD-PTM--YKDLLNLHSNI--VHPSGMYMNPLLYANQNPNAAGYNQGTGGVP 1283

  Fly  1501 PRVLTPTQAATPAVPA 1516
            |..........||.||
  Fly  1284 PMAGGSVAHGPPAAPA 1299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ino80	NP_732413.1	DBINO	313..438	CDD:290603	23/152 (15%)
		SNF2_N	538..840	CDD:278600	60/338 (18%)
		DEXDc	555..700	CDD:238005	42/173 (24%)
		Helicase_C	1156..1269	CDD:278689	47/136 (35%)
XNP	NP_651398.1	DTHCT	258..335	CDD:285332	16/103 (16%)
		SNF2_N	458..779	CDD:278600	85/538 (16%)
		DEXDc	483..646	CDD:238005	42/173 (24%)
		Helicase_C	913..1035	CDD:278689	41/121 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467196
Domainoid	1	1.000	47	1.000	Domainoid score	I705
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.930