Protein Alignment Ino80 and CG7376

DIOPT Version :10

• Sequence 1: NP_732413.1
• Gene: Ino80 / 42314
• FlyBaseID: FBgn0289122
• Length: 1638
• Species: Drosophila melanogaster
• Sequence 2: NP_648034.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Alignment Length: 1328
• Identity: 236/1328 - (17%)
• Similarity: 412/1328 - (31%)
• Gaps: 569/1328 - (42%)

  Fly   401 QRKQDVELIEVKRQQ----RKLNFLITQTELYAHFMSKKLGQGSEEDQLRILSQLDEETNARLAA 461
            :.|::: ||.:::.|    |||.|...:.|           .||   .:.:||.  |:|:.| |.
  Fly    39 EHKEEI-LICIEKCQNARTRKLKFRSIRQE-----------SGS---CILVLSH--EQTHVR-AR 85

  Fly   462 QDDYDAGEMKL--------------LAQENAEAAMQRDLD---KTRAFD-VFAKKKEKEEEEQAQ 508
            :.:.:.||..|              :||:..|  .:|.|.   .|:.:| ::.|.::....||.
  Fly    86 EIEMEVGEQVLPLFFKDFRGSLEFEVAQQEKE--HKRPLKTYVTTKLYDALYEKHRQTVHVEQE- 147

  Fly   509 ESVEDIKPEPRPEMKDLPQPKMFKGTLKGYQIKGMTWLANIYDQ---------------GIS--- 555
                          :.|..||.|:..|:.||.:.::|:.....|               ||:
  Fly   148 --------------RSLDLPKRFQSQLRKYQQRTVSWMLGREQQITQVPANFIVLHAIDGITRVF 198

  Fly   556 -----------------------GILADEMGLGKTVQSIAFL----------------------- 574
                                   |||||||||||||:.:|.|
  Fly   199 KHKYCLQFYPFEEEIPKISLPPGGILADEMGLGKTVEFLAMLLMNPRPQDSYRNDYWHQRLEEFS 263

  Fly   575 -----------------CHIAEHYG-------------------------------VW------- 584
                             |...:.:|                               .|
  Fly   264 DEVPLKRSRISKKDEVFCICTKKHGKRVQCTKCRRWQHEMCMTISEKSDLPHLCPSCWSELVKSG 328

  Fly   585 ------GPFLVISPASTLHNWQQEMSRFV-PDFKVVPYWGSPAERKILRQFWDQKHLHTRD-ASF 641
                  |..:::||.:....|.:|:.:.: |..||:.|:|      :...||    :...| |.:
  Fly   329 ERLVESGATIIVSPNAIKMQWFEEIHKHISPSLKVLLYFG------LHSTFW----VSPFDLAQY 383

  Fly   642 HVVITSYQLV------VSDYK----------YFN------RIKWQYMVLDEAQAIKSAASQRWKL 684
            .||:|.|.::      .:|:|          |..      .:.|..:.|||||.::|:.|...::
  Fly   384 DVVLTDYTILRNEIYHTTDFKSDRQMRHQQRYMRPNSPLLMVNWWRVCLDEAQMVESSTSAAAEM 448

  Fly   685 LLGFSCRNRLLLSGTPIQNSMAELWALLHFI-MPTLFDSHDEFNEWFSKDIESHAENKTGIDEKQ 748
            :......||..::||     :.||..||.|: .|.:....|   .|.:.|.......|
  Fly   449 VRMLPAINRWAVTGT-----IDELPPLLEFVGRPEVCRPPD---AWQTVDKAFQLNYK------- 498

  Fly   749 ISRLHMILKPFMLRRIKKDVENELS--DKIEIMVYCPLTIRQKLLYRALKQKIRIEDLL----HL 807
            ...|..:|:..:.|..|..||:||.  .:.|::....|:..:.|.||....|...:.|.    |.
  Fly   499 CEPLLELLEHSLWRTCKSKVEHELGIPPQTEVVHRLELSNVESLYYREEHLKCHEQFLAAVAKHT 563

  Fly   808 TSGSTTTSSSSSAS-NLMNLV----MQFRKVCNHPELFERRDARSPFFMRCAEYTIPRLIHEEGL 867
            ...:..:|..:|.| .|:.::    ::.|:.|:.|.:|....:.:.:            :|.:.|
  Fly   564 RHNADNSSCLASISPQLLRIILKPFLRIRQTCSVPVVFNSNVSSTDY------------LHPQDL 616

  Fly   868 IHRMLPSRKH------------------------------LLYNRFNIFKSEYIQRSLFED--VN 900
            :.|:..:.::                              ..||......:||.::::..|  :.
  Fly   617 LARLKSNNENECKTELRTWASSYNGLAAIYFIKNDFPQAIKYYNLLLKLANEYNEQNISVDSVLQ 681

  Fly   901 VNSCFGFTRLCDLSVGD---------------------MVEVTLNGLIDFLLHYRRVLEKYPLLA 944
            :::.:...:...|:..:                     .:|.....|...|..|...|||...|.
  Fly   682 IHAIYNLLQASSLAPAEHKLTELEHKKYQAQMSRLEWKYLEDNTRVLESALSSYNENLEKVSELE 746

  Fly   945 YRRFWWKKQPDSRYQLLEPMLENKLALDYMPPNSVLKNFIFTAMTANESSVYAFGDYFTYNMQ-E 1008
                  |:...|...||..|:.:|.:|.....|.|.                  .|:|..|:. |
  Fly   747 ------KRFEGSTLDLLATMVNHKTSLHDAIWNKVR------------------DDFFRQNISVE 787

  Fly  1009 TIEH-----------RVIRSKILKKKTSLIEEME---DVSKQKLE------IESVEVQTKSNAKS 1053
            .:|:           .:..:|:...|::||.|.|   .|.:|..|      :.|:|:   .|...
  Fly   788 RLENVNSMAGMLYFMDIWHNKLQNLKSTLIAEFEFLKGVMQQACEAIKTGVLLSMEI---INFIE 849

  Fly  1054 DVKVTTLL-LLPEFPHRPRKPRKY-----------------------------VCEPLSMPRILY 1088
            :|.|..|. :|.....:|.||:|:                             |.|.|..|.:..
  Fly   850 NVTVCHLTDILDANKDKPVKPKKHRYCRLCLIRDSLNQFECLLFAKKLDEKATVTEGLENPSMEI 914

  Fly  1089 DLGQKVQAVHRYLYCDSRSAAWSQIRHNQCENSQGRELVS-----------------------SG 1130
            ..   ::::..:|......:.|.:    :|::.  .||:|                       ..
  Fly   915 SF---IKSIFAFLRSKQDFSEWKE----ECQSK--LELLSCLQDLVKFQIKYWIEVEYMVKAFDE 970

  Fly  1131 LALCKPHGGWSSIVVPDKETLITDAGKLFVLDNLLTRLKANGHRVLI-----------YSQMTKM 1184
            |.:||            ...|:||..:           :.:.:|:|.           |:..|..
  Fly   971 LEMCK------------MRILLTDDPE-----------EQSNYRILACQLDEQLQFNQYNLQTSQ 1012

  Fly  1185 IDLLE-----EYMWHRKH----------------RYM-----------------RLDGSSKIS-- 1209
            ::...     :|:.|.|.                ||:                 |.:|.:.::
  Fly  1013 LNFTRLCGRLKYLKHLKEDSADKPCPICQTQDDVRYVMMVCGHFVCQHCLDSMRRKNGRAGVTKC 1077

  Fly  1210 -----------------ARRDMVADFQTRAD-----------------IFVF------------- 1227
                             |.:.::.||.|:..                 |.||
  Fly  1078 PLCRQDSPQLYYSVRPGAHKSIIGDFSTKISSVVELVLKIKGENEQEKIIVFSQWQAILIEIARA 1142

  Fly  1228 ------------------------------LLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAM 1262
                                          |:....|..|:||..|..|...:...||..::||:
  Fly  1143 LSLNGIQFRNKCTNKDFDDFKNPLSNVTCLLMPLSKGSKGLNLIEATHVFLVEPILNPGDERQAI 1207

  Fly  1263 DRAHRLGQTKQVTVYRLICKGTIEERIL 1290
            .|.||.||.:...|:|.|...||||.||
  Fly  1208 GRIHRFGQKRPTKVHRFIVNETIEENIL 1235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ino80	NP_732413.1	HepA	364..>855	CDD:440319	126/636 (20%)
		DEXQc_INO80	535..763	CDD:350760	70/377 (19%)
		SF2_C_SNF	1146..1280	CDD:350180	39/261 (15%)
		PHA03247	<1535..1637	CDD:223021
CG7376	NP_648034.1	DEXQc_SHPRH	160..513	CDD:350828	70/377 (19%)
		PHD_SF	281..320	CDD:473978	2/38 (5%)
		TPR	636..669	CDD:197478	2/32 (6%)
		RING_Ubox	1036..1082	CDD:473075	4/45 (9%)
		SF2_C_SNF	1104..1225	CDD:350180	22/120 (18%)