Protein Alignment Ino80 and CG4049

DIOPT Version :10

• Sequence 1: NP_732413.1
• Gene: Ino80 / 42314
• FlyBaseID: FBgn0289122
• Length: 1638
• Species: Drosophila melanogaster
• Sequence 2: NP_611885.3
• Gene: CG4049 / 37860
• FlyBaseID: FBgn0034976
• Length: 1669
• Species: Drosophila melanogaster
• Alignment Length: 1515
• Identity: 309/1515 - (20%)
• Similarity: 528/1515 - (34%)
• Gaps: 425/1515 - (28%)

  Fly   299 KRKNPAALAARRRRIWQIMSKKESGRLQRIKSNNHKEMLANCKRVAGMCAKVVRQRAINSQRIMK 363
            ||||.|...       |..:||.|......|.|:|..     |.:          |.:.::..:.
  Fly   171 KRKNSAGED-------QAANKKLSMAAAEEKKNSHLR-----KNI----------RDVMNENNLD 213

  Fly   364 ETVWRAKRLTREMLAYWKRYERVERDQRRKQEREAEEQRKQDVELIEVKRQQRKLNFLITQ---- 424
            .|...|:|...|.||      ||...|:..:|.:.:...||...::::...:...:..:..
  Fly   214 TTTLAAQREESERLA------RVAGQQKSMREIQKQVVHKQIFRILQLDESEGIESCAVANPVEH 272

  Fly   425 ------------TELYAHFMSKKLGQGSEEDQLRILSQLDEETNARLAAQDDYDAGEMKLLAQEN 477
                        ::.:....|..|..||.||   :|.:......:.:...||....:..||::|.
  Fly   273 HPPVDFPEEEIASDTFDDSNSSSLSGGSIED---VLHKGASVQPSEVVTIDDSSDDDCILLSEEE 334

  Fly   478 AEAAMQRDLDKTRAFD-----VFAKKKEKEEEEQAQESVEDIKPEPRPEMKDLPQPKMFKGTLKG 537
            .|   :.|.|...:.|     :..|......:|..|..|....||....:...||   ....:|.
  Fly   335 EE---EDDEDLNESDDATNSGMHVKDIYNVPDENGQVVVNMAHPEGEETLYLAPQ---IAKVIKP 393

  Fly   538 YQIKGMTWLANIYD------------QGISGILADEMGLGKTVQSIAFLCHIAEHYGVWGPFLVI 590
            :||.|:.:|   ||            .|...|||..||||||:|.::| |.|...:......|.:
  Fly   394 HQIGGVRFL---YDNIIESTRRYNKSSGFGCILAHSMGLGKTLQVVSF-CDIFLRHTSAKTVLCV 454

  Fly   591 SPASTLHNWQQEMSRFVPDF---------------------------KVVPYW---------GSP 619
            .|.:||.||..|.:.::|.:                           ||:..|         |..
  Fly   455 MPINTLQNWLSEFNMWIPRYSTDSNVRPRNFDIFVLNDQQKTLTARAKVILNWVHDGGVLLIGYE 519

  Fly   620 AERKILRQFWDQKHLHTR------------DASFHVVITSYQLVVSDYKYFNRIKWQYMVLDEAQ 672
            ..|.:.     .|.:.||            |:|..::...|:.:|....       ..::.||..
  Fly   520 LFRLLA-----LKLVKTRKRKGSVIRPDGMDSSSDLMNLVYEALVKPGP-------DLVICDEGH 572

  Fly   673 AIKSAASQRWKLLLGFSCRNRLLLSGTPIQNSMAELWALLHFIMPTLFDSHDEFNEWFSKDIESH 737
            .||::.:.....|.....|.|::|:|.|:||::.|.|.::.|:.|....:..||...|.:.|::.
  Fly   573 RIKNSHAGISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRPNYLGTRTEFCNMFERPIQNG 637

  Fly   738 AENKTGIDEKQISR-----LHMILKPFMLRRIKKDVENELSDKIEIMVYCPLTIRQKLLYRALKQ 797
            ....:..|:.::.|     ||.:|..|:.||....::..|..|.|.::...:|..|:.||...
  Fly   638 QCVDSTPDDIKLMRYRAHVLHSLLLGFVQRRSHTVLQLTLPQKYEYVILVKMTAFQRKLYDTF-- 700

  Fly   798 KIRIEDLLHLTSGSTTTSSSSSASNLMNLVMQFRKVCNHPELFERRDARSPFFMRCAEYTIPRLI 862
                         .|....:.:..|.:.......|:.|||:
  Fly   701 -------------MTDVVRTKAFPNPLKAFAVCCKIWNHPD------------------------ 728

  Fly   863 HEEGLIHRMLPSRKHLLYNRFNIFKSEYIQRSLFEDVNVNSCFGFTRLC----DLSVGDMVEVTL 923
                           :|||                         |.:.|    ||.:.:  |||.
  Fly   729 ---------------VLYN-------------------------FLKKCETDLDLEIDE--EVTK 751

  Fly   924 NGLIDFLLHYRRVLEKYPLLAYRRFWWKKQPDSRYQLLEPMLENKLALDYMPPNSVLKNFIFTAM 988
            ....             |::       :...||...|..| ||.|:.....|.||     |.|..
  Fly   752 GAAT-------------PIV-------EPSADSSLSLASP-LEKKINGSGDPINS-----IETFS 790

  Fly   989 TANESSVYAFGDYFTYNMQETIEHRVIRSKILKKKTSLIEEMEDVSKQKLEIESVEVQTKSNAKS 1053
            .|...::        :|:..:.:   :.:|.|.|..|..:|    ..:.|...|...:.|:|...
  Fly   791 KAENQTL--------FNIPASSD---LNAKYLNKSPSFYDE----KPEPLNYGSFGSEGKNNYWM 840

  Fly  1054 D------------VKVTTLLLLPEFPHRPRKPRKYVCEPLSMPRILYDLG-QKVQAVHRYLY--C 1103
            |            :|.|...:...|            |.::....:.||. .:::.|...:.  |
  Fly   841 DSSILPKPGCVEVIKQTDTNMSSNF------------ESITGSSEIVDLDTNEIKTVETTIQAPC 893

  Fly  1104 DSRSAAWSQIRHNQCE-------NSQGRELVSSGLALCKPHG--------------GWSSIVVPD 1147
            .:...      .|.|.       |:.|.: .|||:|..:|..              .|:..::.:
  Fly   894 SNNQL------DNGCNAGKPSEWNAAGSK-NSSGVAAAEPFKKLLKSKQRNEEFSCSWAVDLMKN 951

  Fly  1148 KET-LITDAGKLFVLDNLLTRLKANGHRVLIYSQMTKMIDLLEEY-----------MWHRKHRYM 1200
            ..: ||:::.|:.:...:|......|.|:|::||....::|||.|           :|.:...|.
  Fly   952 YVSGLISNSPKMEIFFCILKESLNLGDRILLFSQSLLTLNLLEVYLKSSYVPGSNQLWTKNSSYF 1016

  Fly  1201 RLDGSSKISARRDMVADFQTRADIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRA 1265
            |||||:....|..:|.:|...:::.:||:|||||.||||||.|:.||.:|:.|||..|.||:.|.
  Fly  1017 RLDGSTSSQERERLVNEFNANSNVKLFLISTRAGSLGINLTGANRVIIFDASWNPCHDTQAVYRI 1081

  Fly  1266 HRLGQTKQVTVYRLICKGTIEERILQRAREKSEIQRMVISGGNFKPDT-LKPKEVVSLLLDDEEI 1329
            :|.||||...|||::....:|::|..|..:|..:...::...|  |:. |..|::.:|..|.:..
  Fly  1082 YRYGQTKPCFVYRIVMDRCLEKKIYDRQIKKQGMSDRIVDECN--PEAHLSMKDITNLCQDYDSD 1144

  Fly  1330 EMKYRQEAKLQSSSPIPAATQSERKRRHPQKDVNMGGTTIAATSATQNP-----DDDVPSCSSAA 1389
            |....:..|.......|.:...|..:   ....||...  |:..:...|     |.:.|...:.|
  Fly  1145 EDTVEEVNKSTGDLSKPGSPSEEGSK---PGSANMSPN--ASNKSNNGPTKPLDDQNTPKSPNGA 1204

  Fly  1390 KRIKLETEED-------FIDVGITSSASSVGTDSNHPTLSQETYVPGATCVQQTEIDSENEALVV 1447
            ....::||::       .:| ||.::.    .|.:...:::|.::              :|:|:|
  Fly  1205 SHSPIKTEKNDGQEHAVHVD-GIINTI----LDMHRHCVTKEPFM--------------HESLLV 1250

  Fly  1448 DGDSPTMLGQNESMNF-----LDDLSGI------SPMRRRH---HPRGTRRGRPRGSTRRGGGHG 1498
            | .....|.|.|....     |:..:.:      :|.:..:   :..||...:|...
  Fly  1251 D-QKDRKLSQAEKRQAHRSYELEKKAAVNQRFTYAPAKMNYKIVNNDGTVITKPMNQ-------- 1306

  Fly  1499 SIPRVLTPTQAATPA-----VPATASQAAAAGTGAAAGTSSPLPQQEVSGGGDNAGVPLHEEE-- 1556
               ::.|.|.::|..     :||...|....   .|...:.||.....:...|.|.:.|...:
  Fly  1307 ---QIKTNTSSSTGGRSTRWIPADVWQRQGM---TAQEMTLPLDVVIPTNSADKANIILKAGQRV 1365

  Fly  1557 ---------YRTSPSGQSPGV--SCKRGPGRPRSKTATPISRGTRGAPRARRPMGPLLVPLGRSP 1610
                     |....||:...:  :.|..|.:........|:  ..|.....:|..|.......:.
  Fly  1366 MVLKSAKGIYMQLDSGKIIAIRTTAKTEPEKTNKDDVIDIT--DDGDTDTTKPQSPEEDVKDLTA 1428

  Fly  1611 DDTP-----PSSSPATSRAP 1625
            ||.|     ..|:|||:..|
  Fly  1429 DDEPRVVKNKESNPATTSRP 1448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ino80	NP_732413.1	HepA	364..>855	CDD:440319	118/576 (20%)
		DEXQc_INO80	535..763	CDD:350760	67/292 (23%)
		SF2_C_SNF	1146..1280	CDD:350180	55/145 (38%)
		PHA03247	<1535..1637	CDD:223021	22/109 (20%)
CG4049	NP_611885.3	DEXHc_ARIP4	391..653	CDD:350827	63/277 (23%)
		HepA	<392..1121	CDD:440319	194/885 (22%)