Protein Alignment Ino80 and Iswi

DIOPT Version :10

• Sequence 1: NP_732413.1
• Gene: Ino80 / 42314
• FlyBaseID: FBgn0289122
• Length: 1638
• Species: Drosophila melanogaster
• Sequence 2: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Alignment Length: 967
• Identity: 248/967 - (25%)
• Similarity: 375/967 - (38%)
• Gaps: 387/967 - (40%)

  Fly   395 EREAEEQRKQDVELIEVKRQQRKLNFLITQTELYAHFMSKKLGQGSEEDQLRILSQLDEETNARL 459
            |:|||...|     ||..| .|:.:||:.|||::.|||                      ||:
  Fly    30 EKEAEFDNK-----IEADR-SRRFDFLLKQTEIFTHFM----------------------TNS-- 64

  Fly   460 AAQDDYDAGEMKLLAQENAEAAMQRDLDKTRAFDVFAKKKEKEEEEQAQESVEDIKPEPRPEMKD 524
            |.......|..|.:          :|.||.:  ||...:..|.|:|:.:|.:.:..........|
  Fly    65 AKSPTKPKGRPKKI----------KDKDKEK--DVADHRHRKTEQEEDEELLAEDSATKEIFRFD 117

  Fly   525 LPQPKMFKGTLKGYQIKGMTWLANIYDQGISGILADEMGLGKTVQSIAFLCHIAEHYGVWGPFLV 589
            .....:..|.::.|||:|:.|:.::|:.||:||||||||||||:|:|:.|.::.......||.:|
  Fly   118 ASPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIV 182

  Fly   590 ISPASTLHNWQQEMSRFVPDFKVVPYWGSPAERKILRQFWDQKHLHTRD----ASFHVVITSYQL 650
            |.|.|||.||..|..::.|..:.|...|..          |.::...||    ..:.|.:|||::
  Fly   183 IVPKSTLQNWVNEFKKWCPSLRAVCLIGDQ----------DTRNTFIRDVLMPGEWDVCVTSYEM 237

  Fly   651 VVSDYKYFNRIKWQYMVLDEAQAIKSAASQRWKLLLGFSCRNRLLLSGTPIQNSMAELWALLHFI 715
            .:.:...|.:..|:|:|:|||..||:..|:..::|..|...||||::|||:||::.||||||:|:
  Fly   238 CIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFL 302

  Fly   716 MPTLFDSHDEFNEWFSKDIESHAENKTGIDEKQISRLHMILKPFMLRRIKKDVENELSDKIEIMV 780
            :|.:|:|.::|:|||:       .|....|:..|:|||.:||||:|||:|.:||..|..|.|:.:
  Fly   303 LPDVFNSSEDFDEWFN-------TNTCLGDDALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKI 360

  Fly   781 YCPLTIRQKLLYRALKQKIRIEDLLHLTSGSTTTSSSSSASNLMNLVMQFRKVCNHPELFERRDA 845
            :..|:..|:..|    .|:.::| :.:.:|    :.......|.|::||.||..|||.||:..:.
  Fly   361 FVGLSKMQRDWY----TKVLLKD-IDVVNG----AGKVEKMRLQNILMQLRKCTNHPYLFDGAEP 416

  Fly   846 RSPFFMRCAEYTIPRLIHEEGLIHRMLPSRKHLLYNRFNIFKSEYIQRSLFEDVNVNSCFGFTRL 910
            ..|       ||                :..||:||
  Fly   417 GPP-------YT----------------TDTHLVYN----------------------------- 429

  Fly   911 CDLSVGDMVEVTLNGLIDFLLHYRRVLEKYPLLAYRRFWWKKQPDSRYQLLEPMLENKLALDYMP 975
                                                                             
  Fly   430 ----------------------------------------------------------------- 429

  Fly   976 PNSVLKNFIFTAMTANESSVYAFGDYFTYNMQETIEHRVIRSKILKKKTSLIEEMEDVSKQKLEI 1040
                                                                             
  Fly   430 ----------------------------------------------------------------- 429

  Fly  1041 ESVEVQTKSNAKSDVKVTTLLLLPEFPHRPRKPRKYVCEPLSMPRILYDLGQKVQAVHRYLYCDS 1105
                                                                             
  Fly   430 ----------------------------------------------------------------- 429

  Fly  1106 RSAAWSQIRHNQCENSQGRELVSSGLALCKPHGGWSSIVVPDKETLITDAGKLFVLDNLLTRLKA 1170
                                                             :||:.:||.||.:|:.
  Fly   430 -------------------------------------------------SGKMAILDKLLPKLQE 445

  Fly  1171 NGHRVLIYSQMTKMIDLLEEYMWHRKHRYMRLDGSSKISARRDMVADF-QTRADIFVFLLSTRAG 1234
            .|.||||:||||:|:|:||:|...|.:.|.||||.:....|...:.:| ...:..|:|:||||||
  Fly   446 QGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAG 510

  Fly  1235 GLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAREKSEI 1299
            ||||||..||.||.|||||||.:|.||||||||:||.|||.|:|||.:.|:||:|::||..|..:
  Fly   511 GLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRL 575

  Fly  1300 QRMVISGGNF---KPDTLKPKEVVSLL--------------LDDEEIE-MKYRQEAK 1338
            .:|||.||..   :.:.|...|:::::              :.||:|: :..|.|||
  Fly   576 DKMVIQGGRLVDNRSNQLNKDEMLNIIRFGANQVFSSKETDITDEDIDVILERGEAK 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ino80	NP_732413.1	HepA	364..>855	CDD:440319	149/463 (32%)
		DEXQc_INO80	535..763	CDD:350760	90/231 (39%)
		SF2_C_SNF	1146..1280	CDD:350180	70/134 (52%)
		PHA03247	<1535..1637	CDD:223021
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	239/945 (25%)