Protein Alignment Ino80 and Chd1

DIOPT Version :10

• Sequence 1: NP_732413.1
• Gene: Ino80 / 42314
• FlyBaseID: FBgn0289122
• Length: 1638
• Species: Drosophila melanogaster
• Sequence 2: NP_001245851.1
• Gene: Chd1 / 33505
• FlyBaseID: FBgn0250786
• Length: 1900
• Species: Drosophila melanogaster
• Alignment Length: 1706
• Identity: 381/1706 - (22%)
• Similarity: 594/1706 - (34%)
• Gaps: 635/1706 - (37%)

  Fly    41 SLRKPLSSDEETDDEHVVKREHDVQD------SDDSSTVGVVRMKQSSKRKSRLLASKEERQSVK 99
            ||.|| ..:||.|:|....::....|      ||.|:.|.......||:.:......|..||:.|
  Fly   144 SLPKP-EQNEEEDNETEAGQQQPASDASADESSDSSANVSPTSSSSSSEEEEEDYRPKRTRQARK 207

  Fly   100 ----AQLYNFNDLTSDREWLYDLLLSDTESDDPTITEDEYVQQLLREHVREQRQRKNYYKKAANA 160
                |:.........:::..:|   || |||:...::||
  Fly   208 PPTAAEKSKKAPAPKNKKKTWD---SD-ESDESEDSDDE-------------------------- 242

  Fly   161 QYAYYGSGLLSNHDIFAERQLATAGVRKRRRRTKQEILMARLAEAQAGPKPPKQRRRGRKKRDNM 225
                                ::||..||....|.:    ::||:.|       ||||.:
  Fly   243 --------------------VSTAQKRKPAATTSR----SKLAQQQ-------QRRRVK------ 270

  Fly   226 GSPESGEVPPSELGKYTFGDTLPNNEDDD--------EDGGEVDYKRELASLALDYPEEEEIEEE 282
              |.|.|                :::|||        ..|..|.||......|.|  .|:.:|.|
  Fly   271 --PFSSE----------------DSDDDDASKRCATRRKGAAVSYKEASEDEATD--SEDLLEFE 315

  Fly   283 VDVEGGTEGQVTKVRRKRKNPAALAARRRR---IWQIMSKKESGR--------LQRIKSNN---H 333
            .|     |.|..       ..||.|....:   |.:|::::...|        :..|:.|.   |
  Fly   316 YD-----ESQAA-------TTAATAEEEEKCETIERILAQRAGKRGCTGNQTTIYAIEENGFDPH 368

  Fly   334 KEMLANCKRVAGMCAKVVRQRAINSQRIMK-------ETVWRAKRLTREM--------------- 376
                      ||...|........:|.::|       ...|.::...|:|
  Fly   369 ----------AGFDEKQTPDAETEAQFLIKWKGWSYIHNTWESEATLRDMKAKGMKKLDNFIKKE 423

  Fly   377 --LAYWKRYERVERDQRRKQEREAEEQRKQDVELIEVKRQQRKLNFLITQTELYAHF--MSKKLG 437
              .|||:||...|                 |::..|.:        |..|.||...:  :.:.:.
  Fly   424 KEQAYWRRYAGPE-----------------DIDYFECQ--------LELQHELLKSYNNVDRIIA 463

  Fly   438 QGSEEDQLRILSQLDEETNARLAAQDDYDAGEMKLLAQEN---AEAAMQRDLDKTRAFDVFAKKK 499
            :||:.|                      |..|..|...::   ||:..:......|.:...|::.
  Fly   464 KGSKPD----------------------DGTEEYLCKWQSLPYAESTWEDAALVLRKWQRCAEQF 506

  Fly   500 EKEEEEQAQES--VEDIKPEPR-PEMKDLPQPKMFKGTLKGYQIKGMTWLANIYDQGISGILADE 561
            ...|..:...|  ...||..|: ..:|:.|:......||:.||:.|:.||.:.:.:..|.|||||
  Fly   507 NDRESSKCTPSRHCRVIKYRPKFSRIKNQPEFLSSGLTLRDYQMDGLNWLLHSWCKENSVILADE 571

  Fly   562 MGLGKTVQSIAFLCHIAEHYGVWGPFLVISPASTLHNWQQEMSRFVPDFKVVPYWGSPAERKILR 626
            ||||||:|:|.||..:.:.:.::||||.:.|.||:..||:|...:.||..||.|.|....|::::
  Fly   572 MGLGKTIQTICFLYSLFKIHHLYGPFLCVVPLSTMTAWQREFDLWAPDMNVVTYLGDIKSRELIQ 636

  Fly   627 QF-WDQKHLHTRDASFHVVITSYQLVVSDYKYFNRIKWQYMVLDEAQAIKSAASQRWKLLLGFSC 690
            |: |..:  .::...|:.::|:|::|:.|.::...::|..:::|||..:|:..|..:|.|..|..
  Fly   637 QYEWQFE--SSKRLKFNCILTTYEIVLKDKQFLGTLQWAALLVDEAHRLKNDDSLLYKSLKEFDT 699

  Fly   691 RNRLLLSGTPIQNSMAELWALLHFIMPTLFDSHDEFNEWFSKDIESHAENKTGIDEKQISRLHMI 755
            .:|||::|||:|||:.|||||||||||      |:|:.|.:.::: |.    ..::|..:|||..
  Fly   700 NHRLLITGTPLQNSLKELWALLHFIMP------DKFDTWENFEVQ-HG----NAEDKGYTRLHQQ 753

  Fly   756 LKPFMLRRIKKDVENELSDKIEIMVYCPLTIRQKLLYRALKQKIRIEDLLHLTSGSTTTSSSSSA 820
            |:|::|||:|||||..|..|:|.::...:|..||..|:.:..| ..:.|.....|||:|
  Fly   754 LEPYILRRVKKDVEKSLPAKVEQILRVEMTSLQKQYYKWILTK-NFDALRKGKRGSTST------ 811

  Fly   821 SNLMNLVMQFRKVCNHPELFERRDARSPFFMRCAEYTIPRLIHEEGLIHRMLPSRKHLLYNRFNI 885
              .:|:|::.:|.|||..|           :|.:|:.:..|..:|.|
  Fly   812 --FLNIVIELKKCCNHAAL-----------IRPSEFELMGLQQDEAL------------------ 845

  Fly   886 FKSEYIQRSLFEDVNVNSCFGFTRLCDLSVGDMVEVTLNGLIDFLLHYRRVLEKYPLLAYRRFWW 950
                                                                             
  Fly   846 ----------------------------------------------------------------- 845

  Fly   951 KKQPDSRYQLLEPMLENKLALDYMPPNSVLKNFIFTAMTANESSVYAFGDYFTYNMQETIEHRVI 1015
                                                                             
  Fly   846 ----------------------------------------------------------------- 845

  Fly  1016 RSKILKKKTSLIEEMEDVSKQKLEIESVEVQTKSNAKSDVKVTTLLLLPEFPHRPRKPRKYVCEP 1080
                                                                             
  Fly   846 ----------------------------------------------------------------- 845

  Fly  1081 LSMPRILYDLGQKVQAVHRYLYCDSRSAAWSQIRHNQCENSQGRELVSSGLALCKPHGGWSSIVV 1145
                                                                             
  Fly   846 ----------------------------------------------------------------- 845

  Fly  1146 PDKETLITDAGKLFVLDNLLTRLKANGHRVLIYSQMTKMIDLLEEYMWHRKHRYMRLDGSSKISA 1210
               :||:..:|||.:||.||.|||..||||||:|||.:|:|:|.:|:..|...:.|||||.|...
  Fly   846 ---QTLLKGSGKLVLLDKLLCRLKETGHRVLIFSQMVRMLDVLADYLQKRHFPFQRLDGSIKGEM 907

  Fly  1211 RRDMVADFQTR-ADIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQV 1274
            ||..:..|... :..|.||||||||||||||..|||||.:||||||..|.||..||||:||..||
  Fly   908 RRQALDHFNAEGSQDFCFLLSTRAGGLGINLATADTVIIFDSDWNPQNDLQAQARAHRIGQKNQV 972

  Fly  1275 TVYRLICKGTIEERILQRAREKS-----EIQRMVISG-------GNFKPDTLKP--KEVVSLLL- 1324
            .:|||:...::||:|::||::|.     .||||..:|       ||.......|  |:.:|.:|
  Fly   973 NIYRLVTARSVEEQIVERAKQKMVLDHLVIQRMDTTGRTVLDKSGNGHSSNSNPFNKDDLSAILK 1037

  Fly  1325 -------------DDE---EIEMKYRQEAKLQSSSPIPAATQSERKRRHPQKDVNMGGTTIAATS 1373
                         ||:   :|:...|:.........:||             |..:....:|:.:
  Fly  1038 FGAEELFKDEQEHDDDLVCDIDEILRRAETRNEDPEMPA-------------DDLLSAFKVASIA 1089

  Fly  1374 A-TQNPDDDV--PSCSSAAKRIKLETEEDFIDVGITSSASSVGTDSNHPTLSQETYVP--GATCV 1433
            | .:.|.|.|  ...::|.:....:..:|.|..|...:..    |.......::.|:|  ..|..
  Fly  1090 AFEEEPSDSVSKQDQNAAGEEDDSKDWDDIIPEGFRKAID----DQERAKEMEDLYLPPRRKTAA 1150

  Fly  1434 QQTE--------IDSENEALVVDGDSPTMLGQNESMNFLDDLSGISPMRRRHHPRGTRRGRPRGS 1490
            .|.|        ...:.:|....|||...||.:.|.   ||          ..||  :||||...
  Fly  1151 NQNEGKRGAGKGGKGKQQADDSGGDSDYELGSDGSG---DD----------GRPR--KRGRPTMK 1200

  Fly  1491 TRRGGGHGSIPRVLTPTQAATPAVPATASQAAAAGTGAAAGTSSPLPQQEVSGGGDNAGVPLH-- 1553
            .:..|...:..|....:....|| |....:|.|..   |.....||.:.:      ..|..||
  Fly  1201 EKITGFTDAELRRFIRSYKKFPA-PLHRMEAIACD---AELQEKPLAELK------RLGEMLHDR 1255

  Fly  1554 ---------EEEYRTSPSGQSPGVSCKRGPGRPRSKTATPISRGTRGAPRARRPMGPLLVPLGRS 1609
                     |||.:|:.:.::||...:|.......|.. .:|...:......:.:.||...:...
  Fly  1256 CVQFLHEHKEEESKTAATDETPGAKQRRARATFSVKLG-GVSFNAKKLLACEQELQPLNEIMPSM 1319

  Fly  1610 PDDTPPSSSPATSRAP 1625
            |::....|....:|||
  Fly  1320 PEERQQWSFNIKTRAP 1335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ino80	NP_732413.1	HepA	364..>855	CDD:440319	147/516 (28%)
		DEXQc_INO80	535..763	CDD:350760	86/228 (38%)
		SF2_C_SNF	1146..1280	CDD:350180	74/134 (55%)
		PHA03247	<1535..1637	CDD:223021	21/102 (21%)
Chd1	NP_001245851.1	CD1_tandem_CHD1-2_like	339..421	CDD:349313	13/91 (14%)
		CD2_tandem	454..508	CDD:349306	10/75 (13%)
		PLN03142	531..>1066	CDD:215601	217/848 (26%)
		CDH1_2_SANT_HL1	1205..1298	CDD:465731	22/103 (21%)
		DUF4208	1521..1610	CDD:464035