DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dl and arg-1

DIOPT Version :9

Sequence 1:	NP_001247193.1	Gene:	Dl / 42313	FlyBaseID:	FBgn0000463	Length:	833	Species:	Drosophila melanogaster
Sequence 2:	NP_001024615.1	Gene:	arg-1 / 180501	WormBaseID:	WBGene00000185	Length:	357	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	73/216 - (33%)
Similarity:	94/216 - (43%)	Gaps:	34/216 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   406 CPIGYSGPNCDLQLDNCSPNPCINGGSCQPSGKCICPAGFSGTRCETNIDDCLGHQ--CENGGTC 468
            |...|.|..|:..   |.|:|.:: ..|..:|...|..|:.|..|.:||..| .||  |.|||.|
Worm   131 CTSNYYGKRCNRY---CIPSPALH-WECSTNGVRQCAVGWYGDDCSSNIKFC-SHQNPCANGGVC 190

  Fly   469 IDMVNQYRCQCVPGFHGTHCS---SKVDLCLIRPCANGGTCLNLN-NDYQCTCRAGFTGKDCSVD 529
               ...|:|||...|.|..|.   |||...|.|.|.:||||:::| .:.||.|..||.|..|.:.
Worm   191 ---STDYKCQCPSEFLGPRCETPVSKVHCTLERVCKHGGTCVSVNRTNVQCKCIRGFLGSLCEIG 252

  Fly   530 I-DECSSGPCHNGGTCMNRVNSFECVCANGFRGKQCDEESYDSVTFDAHQYGATTQARADGLTNA 593
            | ..||:..|....||..|. || .|||.       .|:|.::|          |....|.|..|
Worm   253 IHGNCSAMRCSVDETCQIRA-SF-AVCAK-------KEKSAETV----------TGTGPDALHFA 298

  Fly   594 QVVLIAVFSVAMPLVAVIAAC 614
            .:.:|.||.....|..|.:.|
Worm   299 MLAVIGVFVCVAGLALVASKC 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dl	NP_001247193.1	MNNL	23..96	CDD:284966
		DSL	164..226	CDD:279722
		EGF_CA	291..329	CDD:238011
		EGF_CA	337..372	CDD:238011
		EGF_CA	453..488	CDD:238011	16/36 (44%)
		EGF_CA	492..526	CDD:238011	15/34 (44%)
		EGF_CA	529..564	CDD:238011	12/35 (34%)
arg-1	NP_001024615.1	DSL	107..171	CDD:128366	12/43 (28%)
arg-1	NP_001024615.1	EGF_CA	174..208	CDD:238011	16/37 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D197806at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920