Protein Alignment Delta and Delta

DIOPT Version :10

• Sequence 1: NP_477264.1
• Gene: Delta / 42313
• FlyBaseID: FBgn0000463
• Length: 833
• Species: Drosophila melanogaster
• Sequence 2: XP_061512000.1
• Gene: Delta / 1279687
• VectorBaseID: AGAMI1_007305
• Length: 1025
• Species: Anopheles gambiae
• Alignment Length: 1050
• Identity: 456/1050 - (43%)
• Similarity: 582/1050 - (55%)
• Gaps: 242/1050 - (23%)

  Fly     1 MHWIKCLLTAFICFT-VIVQVHSSGSFELRLKYFSNDHGRDNEGRCCSGESDGATGKCLGSCKTR 64
            |:||..|...::... ::::|..||.|||.|:||.|:...|:..:|||.::| |.|:|:|:||||
Mosquito     1 MNWIYILACIYVSSQFLLLKVAGSGLFELELRYFQNEKSIDHNEKCCSEKAD-AQGRCIGTCKTR 64

  Fly    65 FRVCLKHYQATIDTTSQCTYGDVITPILGENSVNLTDAQRFQNKGFTNPIQFPFSFSWPGTFSLI 129
            ||.|||||||||||||.||:||||||:|...::|.| |.....:||||||:|||.|.|||.|:||
Mosquito    65 FRACLKHYQATIDTTSPCTFGDVITPVLEGTTLNFT-AISGAKEGFTNPIRFPFEFGWPGYFTLI 128

  Fly   130 VEAWHDTNNSGNARTNKLLIQRLLVQQVLEVSSEWKTNKSESQYTSLEYDFRVTCDLNYYGSGCA 194
            :|||||||.: ..|:...||.||.:|::||||::|..:...|.:|.:.|.||||||.||||:|||
Mosquito   129 IEAWHDTNET-TTRSPGTLISRLSIQRILEVSADWMEDSYNSSHTMIRYAFRVTCDPNYYGAGCA 192

  Fly   195 KFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHIPKCAKGCEHGHCDKPNQCVCQLGWKGALCNE 259
            ..||.|||.|||.|||..||.:||:||.|:||.:.:|..||.||||:|||:|:||.||||.||:|
Mosquito   193 NLCRKRDDQFGHYTCSPIGERVCLSGWLGEYCTVAQCTPGCLHGHCNKPNECICQSGWKGPLCDE 257

  Fly   260 CVLEPNCIHGTCNKPWTCICNEGWGGLYCNQDLNYCTNHRPCKNGGTCFNTGEGLYTCKCAPGYS 324
            |...|.|:||||.|||.|||.||||||:|||||||||||:||.|||||||||:|||||:|.|||.
Mosquito   258 CEPYPGCLHGTCKKPWECICKEGWGGLFCNQDLNYCTNHKPCLNGGTCFNTGQGLYTCQCRPGYK 322

  Fly   325 GDDCENEIYSCDADVNPCQNGGTCIDEPHTKTG-------YKCHCANGWSGKMCEEKVLTCSDKP 382
            |.:||..|.||..  :||.:|.||......:|.       |:||||.||.|:.||.:.:||::||
Mosquito   323 GTECELSITSCSD--HPCLHGATCTSTVDGETSMDADGRKYQCHCAKGWMGRHCEREAITCAEKP 385

  Fly   383 CHQGICRNVRPGLGSKGQ---GYQCECPIGYSGPNCDLQLDNCSPNPCINGGSCQPSGK------ 438
            ||||.|.:|.|...|...   .::|:||.||||..|:::...|..|.|.|||:|..:|.
Mosquito   386 CHQGTCVDVTPSSSSSSSTSANFRCDCPPGYSGTACEIKSGECYSNYCANGGTCHVAGSSSSSSA 450

  Fly   439 -------------------------------------CICPAGFSGTRCETNIDDCLGHQCENGG 466
                                                 |:||.||.|.|||.|:|||:|:.|.|||
Mosquito   451 SSSIMASSQSSSSSSLSALFGSGNSNNNNDGGIGMLMCLCPDGFVGDRCEENVDDCVGNLCLNGG 515

  Fly   467 TCIDMVNQYRCQCVPGFHGTHCSSKVDLCLIRPCANGGTCLNLNNDYQCTCRAGFTGKDCSVDID 531
            ||:|..|.::|||||||.||||..||||||.:||||||.|.||.|||:|.|||||||||||.|:|
Mosquito   516 TCVDADNHFKCQCVPGFIGTHCEEKVDLCLTKPCANGGICTNLENDYRCQCRAGFTGKDCSADVD 580

  Fly   532 ECSSGPCHNGGTCMNRVNSFECVCANGFRGKQCDEESYDSVTFDA---------HQYGATTQAR- 586
            ||.|.||.|||||:|||||::||||.|:||..|:|||...:..||         |.:....|.|
Mosquito   581 ECHSAPCRNGGTCINRVNSYQCVCAGGYRGHSCEEESATVIQRDADIEGSEFHHHHHHPQQQQRH 645

  Fly   587 ------------ADGLTNAQVVLIAVFSVAMPLVAVIAACVVFCMKRKRKRAQEKDDAEARKQNE 639
                        ||||::.|:||||:||::.||:|.||..:|.|:||||:|.|||||||||||||
Mosquito   646 SGGEGVDSSSRTADGLSSGQIVLIAMFSISTPLLAFIATTIVICLKRKRQREQEKDDAEARKQNE 710

  Fly   640 QNA----VATMHH--------------------------NGSGVGVALASA-------------- 660
            |||    .|:.||                          :.:..|..|.|:
Mosquito   711 QNASHNLSASSHHHHHHLQQQQQHQQQQQLHHQQSSSSSSSTSSGALLHSSSQQQQQQQYHNGFH 775

  Fly   661 ----SLGGKTGSNSGLT-FDGGNPNIIKNTWDKSVNNI--------------------------- 693
                |.|.|..|::.|: ||..: ::||||||||:||:
Mosquito   776 NHLQSSGQKRNSSNTLSNFDSSH-HMIKNTWDKSINNMPSPPTTASGSGVSSSGGGGTGGCSAGG 839

  Fly   694 ---------------------CASAAAAAAAAAAADECLMYG-----GYVASVADNNNANSDFCV 732
                                 |..|:|||..:..|....|.|     |.:..::.:::..:....
Mosquito   840 VGGSVGSAALLLSGANMDDNGCLIASAAAVGSNGAGSTGMGGVGGAAGALLYLSTSDDGPTMASC 904

  Fly   733 APLQRAKSQKQLNTDPTLM---------HRGS------------PAGSSAKGASG---------- 766
            :.||||||||||||||:|:         |..|            |:.|:|....|
Mosquito   905 STLQRAKSQKQLNTDPSLLLQQQQQLQNHHHSVILSQTSASSLHPSASAASVGGGTVLSSPVVSS 969

  Fly   767 -GGP---GAAE---GKRISVLGE-GSYCSQRWPSLAAAGVAGACSSQLMAAASVAGSGAGTAQQQ 823
             |.|   |:.:   .||||||.| |..|..||....:|||.|       .:.||.|.
Mosquito   970 TGTPCSNGSGKDMFDKRISVLSESGRLCHPRWNGATSAGVVG-------GSPSVVGP-------- 1019

  Fly   824 RSVVCGTPHM 833
                |..||:
Mosquito  1020 ----CSPPHI 1025

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Delta	NP_477264.1	MNNL	23..182	CDD:462222	87/158 (55%)
		DSL	164..226	CDD:128366	35/61 (57%)
		EGF_CA	291..329	CDD:238011	29/37 (78%)
		EGF_CA	337..372	CDD:238011	14/41 (34%)
		EGF_CA	453..488	CDD:238011	22/34 (65%)
		EGF_CA	492..526	CDD:238011	26/33 (79%)
		EGF_CA	529..564	CDD:238011	24/34 (71%)
Delta	XP_061512000.1	None