Protein Alignment Delta and Ser

DIOPT Version :10

• Sequence 1: NP_477264.1
• Gene: Delta / 42313
• FlyBaseID: FBgn0000463
• Length: 833
• Species: Drosophila melanogaster
• Sequence 2: XP_061507008.1
• Gene: Ser / 1273981
• VectorBaseID: AGAMI1_015117
• Length: 1367
• Species: Anopheles gambiae
• Alignment Length: 941
• Identity: 276/941 - (29%)
• Similarity: 377/941 - (40%)
• Gaps: 243/941 - (25%)

  Fly    12 ICFTVIVQVHSSGSFELRLKYFSNDHGRDNEGRCCSGESDGATGKCLG--SCKTRFRVCLKHYQA 74
            :..|:|..|.|||.|||::...||.:.....|.||....:....:..|  :|.|.|.:|||.||.
Mosquito    15 VILTLISMVSSSGFFELQILEISNTNSHLLSGYCCGLPPEKRQTQTTGCPACATAFSLCLKEYQG 79

  Fly    75 TIDTTSQ---------------------CTYGDVITPILGENSVNLTDAQRFQNKGFTNPIQFPF 118
            |..:..|                     |.:|:..||:||.:|..|||.:       ...|..||
Mosquito    80 TTSSVQQQQQQLKQPAVAVEPQPSGLYGCAFGNASTPVLGGSSFVLTDPE-------VGGITLPF 137

  Fly   119 SFSWPGTFSLIVEAWHDTNNSGNARTNKLLIQRLLVQQVLEVSSEWKTNKSESQYTSLEYDFRVT 183
            :|.|..:|:||::|....|.|.:  .::.||.......|:..|.:|.|.....:...:.|..||.
Mosquito   138 TFRWTKSFTLILQALDMYNESYS--ISERLIDETSFSGVILPSHDWNTLDHIGKSARITYRVRVQ 200

  Fly   184 CDLNYYGSGCAKFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHIPKCAKGCE--HGHCDKPNQC 246
            |..|||.:.|..|||||:|.|||.||.:.|..:|:.||||..|....|..||:  ||.||:|.:|
Mosquito   201 CADNYYNTTCTTFCRPRNDQFGHYTCGKQGNKVCMPGWQGANCEKAICKPGCDQIHGKCDQPGEC 265

  Fly   247 VCQLGWKGALCNECVLEPNCIHGTCN-KPWTCICNEGWGGLYCNQDLNYCTNHRPCKNGGTCFNT 310
            .|:.||:|.|||||::.|.|.||.|| ..|.|||:..|||:.|:||||||..|.||.:||||.||
Mosquito   266 ECRPGWRGPLCNECMVYPGCRHGYCNGSAWQCICDTNWGGILCDQDLNYCGTHEPCMHGGTCENT 330

  Fly   311 GEGLYTCKCAPGYSGDDCENEIYSCDADVNPCQNGGTC--------------------------- 348
            ....|.|.||.|.||..||...:.|..  .||:|||||
Mosquito   331 APDQYRCTCAEGLSGTRCEIVEHPCAP--QPCKNGGTCTLTGNDKSAAVASSTVASIVVRGMRGM 393

  Fly   349 --------------------------IDE----------------------PHTKTGYKCHCANG 365
                                      :|.                      |.....:.|.||.|
Mosquito   394 SSMGKPFGRSAAGTGGGSSAGSGSGTLDSKDQAKSGSSSSSAGLPAPSAGGPQPMKDFVCTCAPG 458

  Fly   366 WSGKMCEEKVLTCSDKPCHQ-GICRNVRPGLGSKGQGYQCECPIGYSGPNCDLQLDNCSPN---- 425
            |:|..||..:..|:|.||.. |.|.::   :|.    ::||||..::|..|...:|.|..|
Mosquito   459 WTGPTCEINIDECADAPCRNGGTCIDL---IGK----FRCECPPQWTGDTCQNDVDECESNVASG 516

  Fly   426 --PCINGGSCQ---PSGKCICPAGFSGTRCETNIDDCLGHQCENGGTCIDMVNQYRCQCVPGFHG 485
              ||||..||:   .|.:|.|..|:.|..|..|:|||:| :|:||.||||:||.|.|.|..|:.|
Mosquito   517 LGPCINAESCRNLPGSFQCTCLEGWGGPTCAKNLDDCVG-KCKNGATCIDLVNDYHCACAVGYTG 580

  Fly   486 THCSSKVDLCLIRPCANGGTCLNLNNDYQCTCRAGFTGKDCSVDIDECSSGPCHNGGTCMNRVNS 550
            ..||:.::.|...||.|||.|::...:::|.|..||:|..|....|.|.|.||.. |.|:|....
Mosquito   581 RDCSTDINECANFPCRNGGECVDFIGNFKCICPLGFSGTLCEEAKDHCVSSPCIE-GQCLNTPGG 644

  Fly   551 FECVCANGFRGKQCDEESYDSVTFD-----AHQYGATTQARADGLTNAQVVLIAVFSVAMPLVAV 610
            :.|.|..|..|:.|:   :..|..:     |::.|.|.....|...:...:::.:
Mosquito   645 YYCHCPPGRAGRHCE---FPRVPCEKGGPCANEAGCTMPTSNDTAISGGPIVVPI---------- 696

  Fly   611 IAACVVFCMKRKRKRAQEKDDAEARKQNEQNAVATMHHNGSGVGVALASASLGGKTGSNSGLTFD 675
              .|                                    ||.| ...|..:|......||.|..
Mosquito   697 --PC------------------------------------SGRG-KCESGPMGTSCVCQSGFTGP 722

  Fly   676 GGNPNIIKNTWDKSVNN-IC----------------ASAAAAAAAAAAADECLMYGGYVASVADN 723
            ....|:.:.|.:...|| ||                .......|......:||..|..:.|....
Mosquito   723 FCQHNVNECTSNPCANNGICIDGEGDYSCECQPGWTGKTCTERAIQCLPGQCLNGGSCIPSQFGG 787

  Fly   724 N-------NANSDFCVAPLQRAKSQKQLNTDPTLMHRGSPAGSS--------AKGASGGGPGAAE 773
            .       .....||..||.:.:.|.        .|.|....|.        |||.|  ||..
Mosquito   788 APHCRCTLGWGGPFCSEPLDQCQGQP--------CHNGGTCESGPGWFRCLCAKGFS--GPDC-- 840

  Fly   774 GKRISVLGEGSYCSQRWPSLAAA----GVAG 800
              ||:|    :.||.: |.|..|    |:.|
Mosquito   841 --RINV----NECSPQ-PCLGGATCKDGIGG 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Delta	NP_477264.1	MNNL	23..182	CDD:462222	49/181 (27%)
		DSL	164..226	CDD:128366	27/61 (44%)
		EGF_CA	291..329	CDD:238011	21/37 (57%)
		EGF_CA	337..372	CDD:238011	15/109 (14%)
		EGF_CA	453..488	CDD:238011	19/34 (56%)
		EGF_CA	492..526	CDD:238011	12/33 (36%)
		EGF_CA	529..564	CDD:238011	12/34 (35%)
Ser	XP_061507008.1	None