Protein Alignment Delta and dner

DIOPT Version :10

• Sequence 1: NP_477264.1
• Gene: Delta / 42313
• FlyBaseID: FBgn0000463
• Length: 833
• Species: Drosophila melanogaster
• Sequence 2: NP_001269415.2
• Gene: dner / 100332110
• ZFINID: ZDB-GENE-130502-1
• Length: 745
• Species: Danio rerio
• Alignment Length: 712
• Identity: 192/712 - (26%)
• Similarity: 296/712 - (41%)
• Gaps: 150/712 - (21%)

  Fly    10 AFICFTVIVQVHSSGSFELRLKYFSND-------HGRDNEGRCCS--GESDGATGKCLGSCKTRF 65
            |:||      |.|.|......::|::.       ||.      ||  ||.:|.      ||:
Zfish    73 AYIC------VCSRGFTGQNCEFFADPCASSPCLHGN------CSQDGEGEGF------SCE--- 116

  Fly    66 RVCLKHYQA--------TIDTTSQCTYGDVITPILGENSVNLTDAQRFQNKGFTNPIQFPFSFSW 122
              |.:.|..        |.| .|:.|: |:...::.|::...|.|..........|.....:...
Zfish   117 --CSEGYSGARCDLPTLTFD-LSESTW-DLAESLVPEHATPATPATPATTTQVLQPTTVLTTTQA 177

  Fly   123 PGTFSLIVEAWHDTNNSGNARTNKLLIQRLLVQQVLEV--SSEWKTNKSESQYT----------- 174
            |.|    :|.|                |....|:|||:  ..:..||::|...|
Zfish   178 PPT----LEPW----------------QPRAGQRVLEILWDDQQITNEAECVSTAGGESAGMMSI 222

  Fly   175 SLEYDFRVTCDLNYYGSGCAKFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHIPKCAKGCEHG- 238
            |||........|....||.|...|.  .:.|:..||.....|.......:...:|..:....|.
Zfish   223 SLELAEETAVKLVGNVSGSAVLWRV--GASGYEQCSVADGTIMWFQQSSEGLVLPDQSLPLGHNY 285

  Fly   239 -----HCDKP---------------NQCVCQLGWKGALCN--ECVLEPNCIHGTCNKPWTCICNE 281
                 |...|               |.|:    ..|:..:  :|..:..|:..:....:.|.|::
Zfish   286 FISVLHVGSPSGPEVTLRLHLLVKTNNCM----EPGSAFSDPQCSGKGKCVTQSSVDTFYCRCDD 346

  Fly   282 GWGGLYCNQDLNYCTNHRPCKNGGTCFN---TGEGL-YTCKCAPGYSGDDCENEIYSCDADVNPC 342
            |:.|::| ::.:.| :.:||:|.|:|.:   ..||. |||.|..|:.|:.|::.:..|.:  .||
Zfish   347 GYSGIFC-EEFDAC-HLKPCENNGSCADLRQRDEGQNYTCTCQTGFEGERCQSLVDHCVS--GPC 407

  Fly   343 QNGGTC---IDEPHTKTGYKCHCANGWSGKMCEEKVLTCSDKPCHQGICRNVRPGLGSKGQGYQC 404
            :||.||   ::.||      |:||.|:.|.|||:|:..|:..|||    .|........|.|:.|
Zfish   408 RNGATCSSSLEGPH------CYCAEGYQGIMCEQKIDPCASGPCH----NNASCSPQGAGLGFSC 462

  Fly   405 ECPIGYSGPNCDLQLDNCSPNPCINGGSCQPSG---KCICPAGFSGTRCETNIDDCLGHQCENGG 466
            .||.|::||.|...:|.|:.|||.: |.|:..|   :|:|..|:.|..||...::||...|:|..
Zfish   463 TCPAGFTGPTCAQLVDFCALNPCAH-GICRSIGTSYRCLCVPGYHGLYCEEEYNECLSAPCQNYA 526

  Fly   467 TCIDMVNQYRCQCVPGFHGTHCSSKVDLCLIRPCANGGTCLNLNNDYQCTCRAGFTGKDCSVDID 531
            ||.|::|.|.|.|...|.|.||....|.||...|.|||.|.:...:..|.|..|:.|::|.||::
Zfish   527 TCRDLINAYECICASQFTGKHCEIYKDPCLKLRCQNGGHCESGGRNASCVCPPGYMGENCEVDVN 591

  Fly   532 ECSSGPCHNGGTCMNRVNSFECVCANGFRGKQCDEESYDSVTFDAHQYGATTQARADGLTN---- 592
            ||.|.|||:||||:::.|.:.|.|..|:.|..|          :.|......|. .|.|||
Zfish   592 ECESNPCHHGGTCIDQSNGYTCHCPPGWVGGSC----------EIHLQWKMAQP-VDSLTNMPRH 645

  Fly   593 AQVVLIAVFSVAMPLVAVIAACVVFCMKR------KRKRAQEKDDAEARKQNEQNAVATMHH 648
            :..::|....||..|:.:|....:..:.|      .|...||..:..:...:..||:|::.|
Zfish   646 SLYIIIGALCVAFVLMLIILIVGICRISRIEYQGSSRHAYQEFYNCRSIDSDFSNAIASIRH 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Delta	NP_477264.1	MNNL	23..182	CDD:462222	38/188 (20%)
		DSL	164..226	CDD:128366	16/72 (22%)
		EGF_CA	291..329	CDD:238011	14/41 (34%)
		EGF_CA	337..372	CDD:238011	14/37 (38%)
		EGF_CA	453..488	CDD:238011	13/34 (38%)
		EGF_CA	492..526	CDD:238011	12/33 (36%)
		EGF_CA	529..564	CDD:238011	16/34 (47%)
dner	NP_001269415.2	None