Protein Alignment Dl and sned1

DIOPT Version :9

• Sequence 1: NP_001247193.1
• Gene: Dl / 42313
• FlyBaseID: FBgn0000463
• Length: 833
• Species: Drosophila melanogaster
• Sequence 2: XP_017212114.1
• Gene: sned1 / 100001751
• ZFINID: ZDB-GENE-100913-1
• Length: 1374
• Species: Danio rerio
• Alignment Length: 866
• Identity: 220/866 - (25%)
• Similarity: 312/866 - (36%)
• Gaps: 284/866 - (32%)

  Fly    76 IDTTSQCTY--GDVITPILGENSVNLTDAQ------RFQNKGFTNPIQFPFSFSWPGTFSLIVEA 132
            |.|..|.|:  |..|||:.....|.:||.:      ::.|..:|..:.........|...:..:|
Zfish   150 IATWHQVTFFGGSSITPVNTFQVVLITDGELSFTIFQYHNITWTTGMHATSGGDLAGLGGIAAQA 214

  Fly   133 WHDTN------NSGNARTNKLLIQRLLVQQVLEVSS--------EW--KTNKSESQYTSLEYDFR 181
            ..:..      |...:||:          .::|:.:        .|  :.:.|..|.........
Zfish   215 GFNAGDGKRYFNIPGSRTD----------DIVEIETTTNVGYPGRWVFRIDDSHVQVGGCNDSAS 269

  Fly   182 VTCDLN--YYGSGCAKFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHI--PKCAK-GCEH-GHC 240
            |..:|.  ..|..|...|...:.||   |||      ||.|:.|..|.|  .:|:. .|:: |.|
Zfish   270 VCANLRPCRNGGRCIDDCITGNPSF---TCS------CLAGFTGRRCQIEVDECSSYPCQNGGTC 325

  Fly   241 -DKPNQ--CVCQLGWKGALC----NECVLEP-----NCIHGTCNKPWTCICNEGWGGLYCNQDLN 293
             ||.|.  |:|.:|:.||.|    :||...|     .||.|..|  :||.|..|:.|..|..|:|
Zfish   326 VDKINHFICLCPVGFIGATCETDIDECQETPCLNGAQCIQGVGN--FTCKCQAGYTGFLCESDIN 388

  Fly   294 YCTNHRPCKNGGTCFN-----------------------------------------------TG 311
            .|.: .||.|||.|.:                                               |.
Zfish   389 ECMS-VPCLNGGVCEDLVNNYTCTCTANFTGSACETELVVADAANQTESCVGEICNKHQICEYTN 452

  Fly   312 EGLYTCKCAPGYSGDDCENEIYSCDADVNPCQNGGTCIDEPHTKTGYKCHCANGWSGKMCEEKV- 375
            .|.|:|.|.|||.||:||.|   |     ||||||.|:|...|     |.|..|::|..|:.:|
Zfish   453 SGNYSCTCMPGYYGDNCEEE---C-----PCQNGGICVDVNGT-----CDCPTGFTGLYCQFEVT 504

  Fly   376 -LTCS-DKPCHQG------------ICRN------------VRP------------GLGSKGQG- 401
             ..|| ::||..|            .|:.            |:|            |...:..|
Zfish   505 QTPCSNNRPCPDGGPCLEYGGTYLCTCQTGAEFDHKDFYPYVQPQSACDSSPCQNGGYCYERDGD 569

  Fly   402 YQCECPIGYSGPNCD-LQLDNCSPNPCINGGSCQ---PSGKCICPAGFSGTRCET-NIDDCLGHQ 461
            |.|||..||.|.:|: ::|..|:.:||.|||||:   .|..|:||..|:|..||. ..|.|....
Zfish   570 YICECKHGYRGKHCERVRLSICASSPCRNGGSCKEEADSYHCVCPYRFTGKHCEVGKPDPCASSP 634

  Fly   462 CENGGTCIDMVNQYRCQCVPGFHGTHCS------------------------------------- 489
            |.|||||...:.:|:|:|.|.|.|.||.
Zfish   635 CRNGGTCFHYIGKYKCECSPSFMGRHCEINRGSNPALEGLDCGPPVKAKHAEVQYSSTTPGSMAL 699

  Fly   490 ------------------------------SKVDLCLIRPCANGGTCLNLNNDYQCTCRAGFTGK 524
                                          .:::.||.:||.|||||.:....|.|.|..||||:
Zfish   700 YLCHPGYTPLTRATQIICSSQGSWSQPPVCEEINECLSQPCMNGGTCRDRVASYLCECEEGFTGQ 764

  Fly   525 DCSVDIDECSSGPCHNGGTCMNRVNSFECVCANGFRGKQCDEESYDSVTFDAHQYGATTQARADG 589
            .|..|:|||.|.||.:|.||.::..|:.|.|..|:.|:.|:.|............|.....|.:.
Zfish   765 RCQTDMDECLSEPCKHGSTCEDQPGSYFCHCQEGYAGQDCEMEQDGCEPNPCLNGGICRGYRRNH 829

  Fly   590 LTNAQVVLIAVFSVAMPLVAVIAACVVFCMKRKRKRAQ--------------------------- 627
            |...:...|......:....|:..|....:.|..:|..
Zfish   830 LCVCKEGYIGDRCQTLENPCVLQPCGNRGVCRSDRRGNYSCACRVGHTGRDCERDLLPPSGLNVL 894

  Fly   628 --EKDDAEAR-KQNE--QNAVATMHHNGSGVGVALASASLG---GKTG----SNSGLTFDGGNPN 680
              |:::.|.| .|::  ||.::         |.|:|.|.:|   .||.    .:|.....|.||.
Zfish   895 RVEENEVELRWDQSDVTQNLIS---------GFAVAFAPVGRVPRKTDFLEKKHSTYVLQGLNPG 950

  Fly   681 IIKNTWDKSVNNICASAAAAA 701
            .:.|....|||:|..|..|.|
Zfish   951 QLYNISTYSVNSIDKSQPAFA 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dl	NP_001247193.1	MNNL	23..96	CDD:284966	8/21 (38%)
		DSL	164..226	CDD:279722	17/65 (26%)
		EGF_CA	291..329	CDD:238011	19/84 (23%)
		EGF_CA	337..372	CDD:238011	13/34 (38%)
		EGF_CA	453..488	CDD:238011	14/34 (41%)
		EGF_CA	492..526	CDD:238011	16/33 (48%)
		EGF_CA	529..564	CDD:238011	15/34 (44%)
sned1	XP_017212114.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D197806at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010