Protein Alignment unc79 and unc79

DIOPT Version :9

• Sequence 1: NP_650795.2
• Gene: unc79 / 42310
• FlyBaseID: FBgn0038693
• Length: 3028
• Species: Drosophila melanogaster
• Sequence 2: XP_012824851.1
• Gene: unc79 / 100486994
• XenbaseID: XB-GENE-983028
• Length: 2738
• Species: Xenopus tropicalis
• Alignment Length: 3167
• Identity: 931/3167 - (29%)
• Similarity: 1407/3167 - (44%)
• Gaps: 762/3167 - (24%)

  Fly    57 LLTVLKDVRTSPHELIRDPLEDPTRMSAYPNLEYGNLYNALTMLIDVAPCIQYGQIVFGKALLQC 121
            |.:||:|   ||.|  |.......::|.||:|:|..||..|..|:|:.|.:|:||...|:::...
 Frog   139 LYSVLRD---SPSE--RGQQSRDAQLSEYPSLDYQGLYVTLVTLLDLVPLLQHGQHDLGQSIFYT 198

  Fly   122 LSCILPFLDKDLIDNLPYLVSSTISVLPPALHQCIINALCYYILPFTITRRSSDEQECQACQ--- 183
            .:|:||||..|::..|||.:.||::..||.||:.||..|....||..|.:.....::..:.:
 Frog   199 TTCLLPFLSDDILSTLPYTMISTLATFPPFLHKDIIEYLSTSFLPMAICKSVEPNEQVGSSRREG 263

  Fly   184 --------SVSSVIMMVLQYSNNPAHHCQLLECLMTLKHNVVKDILCVVAYGTAVSRTSAAKLLF 240
                    |.||::|:.:||:.||.:|||||||||..|..|.||:|.|:|||.:..:..|.::||
 Frog   264 GVPAHVNLSASSMLMIAMQYTTNPVYHCQLLECLMKYKQEVWKDLLYVIAYGPSQVKPPAVQMLF 328

  Fly   241 YYWPAFN--ANLFDRKVLLSKLTNDLVPFTCQREHCPNSGNAEAAKVCYDHSISIAYAPDCPPPL 303
            :|||...  ..:.:.:.|.....|   |..||...|.|:.|..|.|:|.|.|:|:|.. |.||||
 Frog   329 HYWPNLKPPGAITEYRGLQYTAWN---PIHCQHIECHNAINKPAVKMCIDASLSVALG-DKPPPL 389

  Fly   304 YLCIECANEIHREHGSLEFGDILHPMQQVSMVCENKNCRSNEKSAFSICFSTECASFNGNHPIRY 368
            |||.||:..|..:||.... |:|.|..::|.:|:.|||.|:.:.|...|||..|...:||.|:||
 Frog   390 YLCEECSQRIAGDHGEWLI-DVLLPQAEISAICQKKNCSSHVRRAVVTCFSAGCCGRHGNRPVRY 453

  Fly   369 CSQCHSNRHNSRRGG-----DHVVHRSLQP--AWQMDPEMQMHMVESVVSLLRE----AKPLNFE 422
            |.:|||..|::..|.     .|:...|..|  ..:...|..:..||:|:|||:|    |:...:|
 Frog   454 CKRCHSYHHSNEVGAGAAAETHLFQTSPPPINTRECGAEELVCAVEAVISLLKEAEFHAEQREYE 518

  Fly   423 PGKE-----SSSSESKKNGSGITADNISLEERQRLGRYGIWLLVGRCTPTADTPVEVLGRILSML 482
            ..:.     |||..|..|......|:...::| .|.::|||.||..|||:.:||.|.|.|::||:
 Frog   519 MNRRRQMGLSSSHHSLDNADFDNKDDDKHDQR-LLSQFGIWFLVSLCTPSENTPTESLARLVSMV 582

  Fly   483 FHWFHVTAYSYDAAGQVESTIEKLKVDHVCNWLKDICRIHYNVFISCLLPHPPEYARVGGHWETL 547
            |.|||.|||..|  .:|.|.:||||...|..|||.:|.|.::|.:.||||.|.|:|||||:|:..
 Frog   583 FQWFHSTAYMMD--DEVGSLVEKLKPQFVTKWLKTVCEIRFDVMVMCLLPKPMEFARVGGYWDKS 645

  Fly   548 ASRTSHLKEGLQRLICLVPYEVITSEIWDYVMPHWMEAITNDVAEKELNELKIVLSKILDPEMSP 612
            .|..:.|||||.|::||:||.||..::|:.:||.|:|||..:|.:.:|.|.:.||||:.|.|:.|
 Frog   646 CSTVTQLKEGLNRILCLIPYNVINQQVWECIMPEWLEAIRTEVPDTQLKEFREVLSKMFDIELCP 710

  Fly   613 LGFDAKTMYNFVAIRFEKTTAKVQQQALHWLQILTKLEILIPLVQLFAMFGDGVRIMKYGIQHEL 677
            |.|..:.|:.|::.||....:.||:|||.||.:|::|:|::||..|.:||.|||..:|.......
 Frog   711 LPFSMEEMFGFISCRFTGYPSSVQEQALLWLHVLSELDIVVPLQLLISMFSDGVNSVKELANQRK 775

  Fly   678 MREKDAQSQ------SLAKAPKTPCKESKETKADMANP-------PRRSSI-SPVVEDDSGNTSA 728
            :|..|....      |:|..|      .:..:..|.:|       |.||.: ||.       .|.
 Frog   776 VRVNDLAGNIAGHRGSIASDP------GRRVQHSMLSPFPSPFHSPFRSPMRSPF-------RSP 827

  Fly   729 ISDDEAPTNRHTEFS-TDAEHNLTCCILMLDILLKQMELQDVEQHMGIHTSVCENVSRLIKCMVT 792
            ..:...|..|..:|. .|.|.||.|.|||.|::||||||||....||:..|:.:::..:|..::.
 Frog   828 FKNYGHPGGRTIDFDCDDDEMNLNCFILMFDLILKQMELQDDGITMGLENSLSKDIISIINNVLQ 892

  Fly   793 AARVGLSSHVCAL--KVAECAYCEASIMWHQLATKLVQFMAPLNPVRPPDVPIEDIIEEEKSSRK 855
            |...|  ||.|..  |..||:.|::||:.:|:|.:|::.:||...:|        ::|
 Frog   893 APWGG--SHTCQKDEKAVECSLCQSSILCYQMACELLERLAPKEEIR--------LVE------- 940

  Fly   856 SPPESDKEKTRDRDVSLSMAPLPIPLGPLGGFADIFKLDQFFSDDGKIIIMAGPVPVAVPQPEPH 920
             |.:|.:|..                              .||....||...|       :.|
 Frog   941 -PTDSLEESL------------------------------LFSRADFIIATEG-------EEE-- 965

  Fly   921 SVGGVLVHMPHVCSNNENGHSVDSNELRKVHATDEIMTATVETVSEQLDLASILPTDRAIARSIT 985
                         :|.:|.||  .|......:|:...|..|:.           .|||
 Frog   966 -------------NNPKNKHS--DNPGNHTESTEPAATTAVKN-----------DTDR------- 997

  Fly   986 LSDADVGSANVSVTKASVMGENGANGGGACGGGENGSGSEEDEEEEDSDDFWHTSVGKFKFTLDT 1050
                                                                       ||....
 Frog   998 -----------------------------------------------------------KFCYQQ 1003

  Fly  1051 LPQPLQYIHQLLTEIPTIKKPEILYYVLQCLNTMALHGDALAKAAREQRGFFIWCQENLLIKNLW 1115
            ||..|:.|:.:|.|:....:|:||:.:|.||..:.|||:.|..|.::...|..:.||::||.:||
 Frog  1004 LPVTLKLIYTILQEMSKFDEPDILFNMLACLKILCLHGECLYIAKKDHLVFLAYIQEHMLISSLW 1068

  Fly  1116 ELCNAEHSHICQVGVPLLLHCITLPLGSDVFWRVVQEAFHDTDWRVRFTAVERVTVITRFMDSTP 1180
            .:..:|.|.:..:|.|||||.::||.|:|:||.::...|:..||::||.|||:|.|:.||:|...
 Frog  1069 RVLKSEFSQLSSLGAPLLLHALSLPHGADIFWTIINSNFNSKDWKMRFEAVEKVAVLCRFLDIHS 1133

  Fly  1181 LRSEVGLQTALATAFCHLIASMDDINVYVAQRATLYIGTIHDTAIRSLLFCLESQFDLFIVDRPV 1245
            :.....|:.:||.|||..:.:::|:|..||.||.|.:.||...|::.|..||:.|||..:.|||.
 Frog  1134 VTKNHLLKYSLAHAFCCFLTAVEDVNPAVATRAGLLLDTIKRPALQGLCLCLDFQFDTVVKDRPT 1198

  Fly  1246 VLQSVYQLHNSLSDRKMLGWEFFLNRFDTLFVEAQINLEKCG-------DISYLRDLRNSDNGSE 1303
            :|..:..||....|...|.||||:||||||.:|||::|: |.       .|:.:|  .|..|.|:
 Frog  1199 ILSKLLLLHFLKQDIPALSWEFFVNRFDTLSLEAQLHLD-CNKEFPFPTTITAVR--TNVANLSD 1260

  Fly  1304 ALSAKIQKAREALSQSDTSGGMAKTLSASFGTKWPYKRTMSAPASMAPRQDSKFVPEKEKIYSRQ 1368
            |...||::||.|.::..:    .::|..|.......||.:|.|.:::.:
 Frog  1261 AAMWKIKRARFARNRQKS----VRSLRDSVKGPGESKRALSLPETLSTK---------------- 1305

  Fly  1369 VSAPILKRKTSRFGLGQFLGSSSGGASGSSQSVNPATTAASSSRPKPPPCPVHQSAHTAFPYHTH 1433
                                                             .||..:.|.
 Frog  1306 -------------------------------------------------IPVRLTRHE------- 1314

  Fly  1434 HHHPHGHHPYPHPHPHHHPHHHAGSSAHVATTATTSAGLVSTHSQSHQYLVHCVPPSHHSPMPTL 1498
                                                                             
 Frog  1315 ----------------------------------------------------------------- 1314

  Fly  1499 QEAETLLRSQAAADAAAASGSFGGSLGHPGQEAAAVGTGTAGGSAGNPNPHHSFHSHFQKHPSAP 1563
                                          |.|.|:| |||.            .:..|:.|...
 Frog  1315 ------------------------------QSAPALG-GTAE------------QTQAQQSPEND 1336

  Fly  1564 NLLPPPPAPSPSPSTLAFPMHCTCDAAPHPHPQVSGAAATGSAANPDGHIHSLGGLNDDNLIGLL 1628
            |::                        ..|.|:.:|.
 Frog  1337 NII------------------------KDPLPEDAGI---------------------------- 1349

  Fly  1629 SRITELEESDRETIHLLVFMLMQFMSRTDQAYPSEEKPMTKTQNIVLKHLFLLLGHNQIDKTFHT 1693
                     |.:|:|.|:.:||:||:: |::....:....|..|.|.:||::|||.:|.:..|..
 Frog  1350 ---------DHQTVHQLIIVLMKFMAK-DKSSAEADISSAKAFNTVKRHLYVLLGFDQQEGYFTI 1404

  Fly  1694 TPESLRVSAVFNAFLANLPQVLDQNHLIGGLILPSVMQIILYAPNPTSTSGESYQNIVFNYSLWH 1758
            .|:.:|.|..||||:|.:.||:|.|..:|..:||.|:|::.|...|..   ..|.......|||.
 Frog  1405 APQKMRTSTCFNAFIAGVAQVMDYNINLGKHLLPLVVQVLKYCACPQL---RHYFQQPPRCSLWS 1466

  Fly  1759 LEQYPRRNWLFTLLVVLYKYSYTQPPLSGYVIAGIRLIMNSLRGHFHQCRRIPTTTILDIQGVGG 1823
            |:.:.|:.||..|||:||||.|.:..||..|:..|.:.:|:|...:|.|:  |..|       .|
 Frog  1467 LKPHIRQMWLKALLVILYKYPYREADLSKIVLHLIHITVNTLNAQYHSCK--PHAT-------AG 1522

  Fly  1824 AARSRDVSQPSLGTDPDDKEASPPASPMFPSEGTSAASK-SKGNVAFTPKLQHAFRKYNDSSLDA 1887
            ...| |.|..|..::.:.:|.|...........|.|.:| |:...|...::..:..||....::|
 Frog  1523 PLYS-DNSNISRYSEKEKEEDSVFDESDIHDTPTGACNKESQTFFARLKRIGGSKVKYQPVDMNA 1586

  Fly  1888 DETESELVAIPESDLSDSTLHGSSAPGSFDDTI----HFEDVMPRNRRALE-------------Y 1935
            ..:|.||....|             ||:..|:|    ..|.:..:..|:|:             :
 Frog  1587 QRSEIELSEYKE-------------PGNLQDSILRCAREEGIQKKRLRSLKQKSLDIGNTDSLLF 1638

  Fly  1936 T-EEKSTKS--------HKSMITTKVGDTYTTKIKATTTSETLVTTH---TRHSLQEGVRMIV-- 1986
            | :|...||        |.  ||.||.| |..: .:::..|.:|...   ||.|..|..|.::
 Frog  1639 TLDEHRRKSCIDRCDITHP--ITHKVND-YGRQ-NSSSGPENVVANENVSTRESFNETRRPVIPE 1699

  Fly  1987 TPLVGAETTETAIVSPP-----------VDVHRAVT--VRNKSLENAAASTSKMFAAIATNHLKA 2038
            ..|...||.|..|.||.           :|:....|  ...:|:.:.:.|.|.:|.
 Frog  1700 VRLSCMETFEVKIDSPTKPPSPREDLDLIDLSSDSTSGPEKQSMLSNSDSDSLIFE--------- 1755

  Fly  2039 LGALQDMPAAVERKAASSSGSGSRSANGSGNGSGGSAPAAIQASSSAAASKPIGRHKTIVECSAG 2103
                   |....|...|.........|||...|..|.|  |.||..:.:..|:.: .:|.:||..
 Frog  1756 -------PLPPLRIVESDDEEFQLMNNGSIVVSASSTP--ISASVLSLSMMPLVQ-VSIEDCSKD 1810

  Fly  2104 NSSS--------SADDS-----RQKKSQTKSLRRTDKNYGSPDSPLSKMSVMPNPRDEMDESMQ- 2154
            ..:|        ..:|:     ..:|...:..:..|...||..|||:    :...||::.:|..
 Frog  1811 FGTSDFNFNPVLQIEDTPPHSHENQKDFEELCKPGDDQEGSSGSPLT----LKQKRDQLRKSCAL 1871

  Fly  2155 ---SLPPPKSIAALEIPTPERLLPIG-TQDT------------------------------VATL 2185
               ||......|..|..|.|:..|:. |:||                              ...:
 Frog  1872 AELSLDDNSEDAMEENNTGEKSEPLNVTEDTENQTDSEKPDVGNESDTEQNAEPKEEAEEFKIQI 1936

  Fly  2186 VERVRDGLNLPDISHLKQDSLDVSESTKDDVTPSSRTNSPRRLIKQVALESPPNPNAQLPSQPSA 2250
            |.|.|....:. :|.::::.||::.:..|.:.....|.|..   |.:::...|..::..|:..:.
 Frog  1937 VPRQRKQRKIA-VSAIQREYLDITFNILDKLGEQKDTESDS---KGLSILEIPRESSSAPTLDAV 1997

  Fly  2251 DLHTSILKNVQQDLKQNAPEGNGLTTSNSIKR---PRQKLAPFNVDSNAIPDIRSRFAGSWPPPP 2312
            ...||...::....:|......|..|...|.:   ..|..||.|:             .:|.|.
 Frog  1998 VPETSSRSSLTTQYRQMKRGSLGAMTMTQIMKRQLEHQSSAPHNI-------------SNWDPD- 2048

  Fly  2313 FQPVDPEPDDDDEIGAEASNGHGIHSTPHAPRGSSR---------------RVGDYT------IV 2356
                ||:. ..:.:|:.:....|..|.|:...|:::               ...|:|      :.
 Frog  2049 ----DPKA-GHEVLGSISEVSMGRTSIPYIQIGATKSSLLSAPSIVSMFVPAPEDFTDDQPTIMS 2108

  Fly  2357 ERCSDCGAHIEEYTDEEIGIFIVILGTFIHREPAMAAPFLPEILTMTSRICLSSTHAWQGENGPP 2421
            ::|.||||.:|||.:|.:|:.||:|.||||..|.:|||.|.:|:....|:..|:..:.|.|: ..
 Frog  2109 DKCHDCGAVLEEYDEETLGLAIVVLLTFIHLSPDLAAPLLLDIMQSVGRLASSTNFSNQAES-MM 2172

  Fly  2422 LASSAQAVACQFFRCVLHQLAPNGIFLQVFQTQMKMKIRHHHFRSIAKALQDFQDLNSTSPIYMV 2486
            :..:|..||.||.|||.|||||||||.|:||:.:|   .....|::|.:|.||.:|:|.:.:..:
 Frog  2173 IPGNAAGVAKQFLRCVFHQLAPNGIFTQLFQSNIK---DGSFLRTLANSLMDFSELSSFAALSQL 2234

  Fly  2487 CESLTSKKSLPIEQLPV-IFRNMAEYLNLQCVPTEAGVGLAVWSQAMQAMESLLRQVIVIMPSLT 2550
            .|.|.:||:||.....: ...|:|.:  ::.:|.::...|  |:......::...::..::|...
 Frog  2235 LEGLNNKKNLPAGGAMLRCLDNIATF--MEALPMDSPSNL--WTTICNQFQTFFTKLPSVLPLKC 2295

  Fly  2551 NAEYMLDIMAATLRL--NCVPKTLLDPYSKIMAYCVQHTNLEYQTLYELCTLNIRSFSKDRDKNL 2613
            :.:..|.||...|::  :...::||:|:||::::.:|:.......|.|||.|..|:|:|:|||..
 Frog  2296 SLDSSLRIMICLLKIPTSNATRSLLEPFSKLLSFVIQNGVFTLAYLVELCGLCYRAFTKERDKFY 2360

  Fly  2614 LCRQMIFEFVQALKFKSNIPDHNLLTIIGFVLLDAGGTLPP---------GAAPGLPDAAPMMTT 2669
            |.|.:|.:.:||||.||.:||.|||.::.|:..|.|..|..         .:.||...||
 Frog  2361 LTRSVILDLLQALKLKSPLPDTNLLLLVQFICTDVGTKLAESTIIHKQMIASLPGCGTAA----- 2420

  Fly  2670 NSADCLRQYINDVIDFLADFHTLSKIKNFKNGQTSSGLGEDTLGGVLKGAVAQYLALEMSRGNSR 2734
              .:|.||||::::||:||.|||:|:|:... ..|..|.|||.||.||..:||..|:|::|||.|
 Frog  2421 --MECTRQYISELLDFIADMHTLTKLKSHMK-TCSQPLHEDTFGGHLKVGLAQIAAMEITRGNHR 2482

  Fly  2735 DNKAVSRYLPWLNNAPSSLQQGPKEFTECVGHMRLLSWLLLGSLTHMALMQRRQETHSIPTPLPQ 2799
            |||||.||||||.:.||::|||||||.|||.|:|||||||||||||..:..      :.|||
 Frog  2483 DNKAVIRYLPWLYHPPSAMQQGPKEFIECVSHIRLLSWLLLGSLTHGVVCV------NSPTP--- 2538

  Fly  2800 QNSQGTGPAASVHYQHQGVTYSQPVPQEASCHIADHIQVIFAGFAEQSKTSVLHMSSLFHAFTLC 2864
                                 ..|:|.:|..|:|||:.||..||.||||||||||.||||||...
 Frog  2539 ---------------------CMPIPLDAGSHVADHLIVILIGFPEQSKTSVLHMCSLFHAFIFA 2582

  Fly  2865 QLWTVYLEQ--MAHNTNSNAEGSTLGVL--FEFWAKVTPCILQLVSHAKPTVNKDQPQTPLDFQT 2925
            ||||||.||  :|.:..:..|.|...||  .|||::|||.||||::|
 Frog  2583 QLWTVYCEQAAIAPSVQNQNEFSFTAVLTALEFWSRVTPSILQLMAH------------------ 2629

  Fly  2926 QSANSKLSEMVNLHFLSLLEALKDTNSTVLGKLLPMWSPVLSSQTQ-LSDTLHVRLQNVRDYAPD 2989
               |:.:.|||.||.:||:|||::.||||..||:|||.|::.|..: ||..|.:|||.:::....
 Frog  2630 ---NTVMVEMVCLHLISLMEALQECNSTVFVKLIPMWLPMIQSNLKHLSAGLQLRLQAIQNNVNQ 2691

  Fly  2990 Y-------EEQQTYKSEALLKWLQRLQFKMGQIELQAS-TATQFYSI 3028
            .       ..|.|:.|..|.||||..||||.|:|:|:| .|:|||.:
 Frog  2692 QNLRMLQGSAQITHNSAVLRKWLQCTQFKMAQVEIQSSEAASQFYPL 2738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc79	NP_650795.2	UNC-79	78..600	CDD:291442	213/550 (39%)
unc79	XP_012824851.1	UNC-79	153..697	CDD:291442	222/572 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	758	1.000	Domainoid score	I95
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41397
Inparanoid	1	1.050	1109	1.000	Inparanoid score	I233
OMA	1	1.010	-	-		QHG50035
OrthoDB	1	1.010	-	-		D51194at33208
OrthoFinder	1	1.000	-	-		FOG0008504
OrthoInspector	1	1.000	-	-		oto103531
Panther	1	1.100	-	-	LDO	PTHR21696
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6459
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.170