Protein Alignment CG5250 and ATP4B

DIOPT Version :9

• Sequence 1: NP_650793.1
• Gene: CG5250 / 42308
• FlyBaseID: FBgn0038691
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_000696.1
• Gene: ATP4B / 496
• HGNCID: 820
• Length: 291
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 63/286 - (22%)
• Similarity: 108/286 - (37%)
• Gaps: 96/286 - (33%)

  Fly    44 TVCRFIKLLLYFIGFFFVL-GVFTTGLALVMIANHIY-PDRPGCKKFPGLATAPG---------- 96
            |:.|::.:.||::.|:.|: |:|...|.::|.....| ||.....:.||:...|.
Human    33 TLSRWVWISLYYVAFYVVMTGLFALCLYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIV 97

  Fly    97 HHVGDQK------QIM------WSPNNIKDVANIQRAIMRTVKRYGLEGPKR------------- 136
            ::|.|.:      |.:      :||...:|..|.      |.::|..:...|
Human    98 YNVSDNRTWADLTQTLHAFLAGYSPAAQEDSINC------TSEQYFFQESFRAPNHTKFSCKFTA 156

  Fly   137 --LMGCN--IDDSWGYMSGTPCILIKITQALGFQAVTYDDALTLPEYAPDELFDYVVGLGSEERF 197
              |..|:  .|.::|:..|.||.:||:.:.:.|          ||..            ||..|
Human   157 DMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKF----------LPSN------------GSAPR- 198

  Fly   198 NRIWVSCQVI-EPR---VDIQFDYHPVRFFDAEELFTSGNVFLNESSDDDGPTY--KEDPRLRR- 255
                |.|..: :||   ..:|..|:|          .:|...|:..     |.|  |..|....
Human   199 ----VDCAFLDQPRELGQPLQVKYYP----------PNGTFSLHYF-----PYYGKKAQPHYSNP 244

  Fly   256 IISVRLSNIPINEDIQIHCKAWAKNI 281
            :::.:|.|||.|.::.|.||..|:::
Human   245 LVAAKLLNIPRNAEVAIVCKVMAEHV 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5250	NP_650793.1	Na_K-ATPase	<143..281	CDD:298651	35/144 (24%)
ATP4B	NP_000696.1	Na_K_ATPase_bet	2..291	CDD:273446	63/286 (22%)
		immunoglobulin-like	194..291		25/97 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840