Protein Alignment CG5250 and ATP1B1

DIOPT Version :10

• Sequence 1: NP_650793.1
• Gene: CG5250 / 42308
• FlyBaseID: FBgn0038691
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001668.1
• Gene: ATP1B1 / 481
• HGNCID: 804
• Length: 303
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 69/304 - (22%)
• Similarity: 114/304 - (37%)
• Gaps: 122/304 - (40%)

  Fly    48 FIKLLLYFIGFFFVL-GVF--TTGLALVMIANH--IYPDR---PGCKKFPGLATAPGHHVGDQKQ 104
            :.|:||:::.|:..| |:|  |..:.|:.|:..  .|.||   ||..:.|.:         .:.:
Human    32 WFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQI---------QKTE 87

  Fly   105 IMWSPNNIKD----VANIQRAI-----------------------------------MRTVKRYG 130
            |.:.||:.|.    |.||.|.:                                   .|.|.|:.
Human    88 ISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFK 152

  Fly   131 LEGPKRLMGCNIDDSWGYMSGTPCILIKITQALGFQ--------AVTYDDALTLPEYAP------ 181
            ||......|.| |:::||..|.|||:||:.:.|||:        ..||......|...|
Human   153 LEWLGNCSGLN-DETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGK 216

  Fly   182 -DELFDYV-----VGLGSEERFNRIWVSCQVIEPRVDIQFDYHPVRFFDAEELFTSGNVFLNESS 240
             ||..|.|     .|||:...|                     |::::
Human   217 RDEDKDKVGNVEYFGLGNSPGF---------------------PLQYY----------------- 243

  Fly   241 DDDGPTYKE--DPR-LRRIISVRLSNIPINEDIQIHCKAWAKNI 281
                |.|.:  .|: |:.:::|:.:|:.::.:|:|.|||:.:||
Human   244 ----PYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENI 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5250	NP_650793.1	None
ATP1B1	NP_001668.1	Na_K_ATPase_bet	1..303	CDD:273446	69/304 (23%)
		immunoglobulin-like	191..303		26/135 (19%)