Protein Alignment CG5250 and ATP1B1

DIOPT Version :9

• Sequence 1: NP_650793.1
• Gene: CG5250 / 42308
• FlyBaseID: FBgn0038691
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001668.1
• Gene: ATP1B1 / 481
• HGNCID: 804
• Length: 303
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 69/304 - (22%)
• Similarity: 114/304 - (37%)
• Gaps: 122/304 - (40%)

  Fly    48 FIKLLLYFIGFFFVL-GVF--TTGLALVMIANH--IYPDR---PGCKKFPGLATAPGHHVGDQKQ 104
            :.|:||:::.|:..| |:|  |..:.|:.|:..  .|.||   ||..:.|.:         .:.:
Human    32 WFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQI---------QKTE 87

  Fly   105 IMWSPNNIKD----VANIQRAI-----------------------------------MRTVKRYG 130
            |.:.||:.|.    |.||.|.:                                   .|.|.|:.
Human    88 ISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFK 152

  Fly   131 LEGPKRLMGCNIDDSWGYMSGTPCILIKITQALGFQ--------AVTYDDALTLPEYAP------ 181
            ||......|.| |:::||..|.|||:||:.:.|||:        ..||......|...|
Human   153 LEWLGNCSGLN-DETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGK 216

  Fly   182 -DELFDYV-----VGLGSEERFNRIWVSCQVIEPRVDIQFDYHPVRFFDAEELFTSGNVFLNESS 240
             ||..|.|     .|||:...|                     |::::
Human   217 RDEDKDKVGNVEYFGLGNSPGF---------------------PLQYY----------------- 243

  Fly   241 DDDGPTYKE--DPR-LRRIISVRLSNIPINEDIQIHCKAWAKNI 281
                |.|.:  .|: |:.:::|:.:|:.::.:|:|.|||:.:||
Human   244 ----PYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENI 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5250	NP_650793.1	Na_K-ATPase	<143..281	CDD:298651	36/160 (23%)
ATP1B1	NP_001668.1	Na_K_ATPase_bet	1..303	CDD:273446	69/304 (23%)
		immunoglobulin-like	191..303		26/135 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940