DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5250 and nkb-1

DIOPT Version :9

Sequence 1:	NP_650793.1	Gene:	CG5250 / 42308	FlyBaseID:	FBgn0038691	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_492506.1	Gene:	nkb-1 / 182726	WormBaseID:	WBGene00007646	Length:	320	Species:	Caenorhabditis elegans

Alignment Length:	352	Identity:	76/352 - (21%)
Similarity:	128/352 - (36%)	Gaps:	113/352 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DAIIYSGPYELGRLRRRRDMRVAEYLYRRSIRTRNADPEMTVCRFIKLLLYFIGFFFVLGVF-TT 67
            :|.:.:|....|..|........|:||.:...|...   .|...:.::::::|.|:..|..| .|
Worm     8 NATLMNGVETTGPARDDVPETFREFLYNKKNGTVMG---RTGKSWFQIIVFYIIFYAFLAAFWLT 69

  Fly    68 GLALVMIANHIYPDRPGCKKFPGLATA----PGHHVGDQKQIMWSPN------NIKDVANIQRAI 122
            .|.:.|  ..:.|..|   :|.|..|.    ||  ||.|..:...|:      |::|..: .:|.
Worm    70 CLTIFM--KTLDPKVP---RFYGKGTIIGVNPG--VGYQPWLKERPDSTLIKYNLRDQKS-YKAY 126

  Fly   123 MRTVKRY---------------------GLE-GPKRL----------MGCNIDDSWGYMSGTPCI 155
            :..:|.|                     .|| .|..|          .||:....:||.||.||:
Worm   127 LEQMKTYLTKYDSNATETRECGAGDSNDDLEKNPDALPCRFDLSVFDKGCSEKSDFGYKSGKPCV 191

  Fly   156 LIKITQALGFQAVTYDDALTLPEYAPDELFD-YVVGLGSEERFNRIWVSCQ-------------V 206
            :|.:.:.:|::...|.:     ...|:|:.| |..|        .|.::|:             .
Worm   192 IISLNRLIGWRPTDYQE-----NSVPEEVKDRYKAG--------SIAINCRGATNVDQEHIGKVT 243

  Fly   207 IEPRVDIQFDYHPVRFFDAEELFTSGNVFLNESSDDDGPTYKEDPRLRRIISVRLSNIPINEDIQ 271
            ..|...|...|:|.       :||.|              |::.     |..|:...||.|:.:.
Worm   244 YMPSNGIDGRYYPY-------VFTKG--------------YQQP-----IAMVKFDTIPRNKLVI 282

  Fly   272 IHCKAWAKNIP------LHMVTVKMLV 292
            :.|:|:|.||.      |.||..:::|
Worm   283 VECRAYALNIEHDISSRLGMVYFEVMV 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5250	NP_650793.1	Na_K-ATPase	<143..281	CDD:298651	32/151 (21%)
nkb-1	NP_492506.1	Na_K-ATPase	27..303	CDD:278704	69/325 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910