Protein Alignment CG11703 and ATP4B

DIOPT Version :10

• Sequence 1: NP_650792.1
• Gene: CG11703 / 42307
• FlyBaseID: FBgn0038690
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_000696.1
• Gene: ATP4B / 496
• HGNCID: 820
• Length: 291
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 61/294 - (20%)
• Similarity: 113/294 - (38%)
• Gaps: 86/294 - (29%)

  Fly    40 DEHKLFGRTALGWMRITGFYLVLYALIVCIVAFWLGIFMLAIIDPNKPRW--------------L 90
            |..::.|||...|:.|:.:|:..|.::..:.|..|.:.| ..:||..|.:              :
Human    25 DTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVLM-QTVDPYTPDYQDQLRSPGVTLRPDV 88

  Fly    91 KGPPGLSMVPN--QNR--SVLAYFTH-IMSEVNPIADRIDDFLNKLNDN---------------A 135
            .|..||.:|.|  .||  :.|....| .::..:|.|.  :|.:|..::.               :
Human    89 YGEKGLEIVYNVSDNRTWADLTQTLHAFLAGYSPAAQ--EDSINCTSEQYFFQESFRAPNHTKFS 151

  Fly   136 IDFFADFNQ------DTTWGYATEKPTVFIKLNKVIGYVPETYDTPDDLPKEAPASLQDTVGKLG 194
            ..|.||..|      |..:|:...||...||:|:::.::|..                      |
Human   152 CKFTADMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSN----------------------G 194

  Fly   195 NTPKIWITCEVTNGPKP-----EMVFYPG---------PYFEASENMRGVTRVVAIQMNKMPENA 245
            :.|:  :.|...:.|:.     ::.:||.         ||:...........:||.::..:|.||
Human   195 SAPR--VDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNA 257

  Fly   246 KTFFSCKVWARNIPID---DDYQGMGIIKFALSM 276
            :....|||.|.::..:   |.|:|.  ::|.|.:
Human   258 EVAIVCKVMAEHVTFNNPHDPYEGK--VEFKLKI 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11703	NP_650792.1	Na_K-ATPase	40..267	CDD:471796	58/283 (20%)
ATP4B	NP_000696.1	Na_K_ATPase_bet	2..291	CDD:273446	61/294 (21%)
		immunoglobulin-like	194..291		22/100 (22%)