Protein Alignment CG11703 and ATP1B2

DIOPT Version :10

• Sequence 1: NP_650792.1
• Gene: CG11703 / 42307
• FlyBaseID: FBgn0038690
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001669.3
• Gene: ATP1B2 / 482
• HGNCID: 805
• Length: 290
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 62/305 - (20%)
• Similarity: 110/305 - (36%)
• Gaps: 106/305 - (34%)

  Fly    32 WSKRIFDIDEHKLFGRTALGWMRITGFYLVLYALIVCI--VAFWLGIFMLAIIDPNKPRWLK--G 92
            |.:.:::...|:..|||...|..|..||||.|..:..:  :..|:   ||..:..:.|::..  .
Human    17 WKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWV---MLQTVSDHTPKYQDRLA 78

  Fly    93 PPGLSMVP-NQNRSVL-------AYFTHIMSEVNPIADRIDDFLNKLNDN--------------- 134
            .|||.:.| .:|..|:       ::..|:        .:::.||...||:
Human    79 TPGLMIRPKTENLDVIVNVSDTESWDQHV--------QKLNKFLEPYNDSIQAQKNDVCRPGRYY 135

  Fly   135 ------AIDF---FADFNQ-----------DTTWGYATEKPTVFIKLNKVIGYVPETYDTPDDLP 179
                  .:::   ...||:           .|.:||:|.:|.||||:|:||.:.
Human   136 EQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKMNRVINFY----------- 189

  Fly   180 KEAPASLQDTVGKLGNTPKIWITCEVTNGPKPE-------MVFYPG---------PYFEASENMR 228
                         .|....:.:||.   |.:.|       .|.:|.         ||:....::.
Human   190 -------------AGANQSMNVTCA---GKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVN 238

  Fly   229 GVTRVVAIQMNKMPENAKTFFSCKVWARNIPIDDDYQGMGIIKFA 273
            ....:||::...:..|.:....|::.|.||..||:..     |||
Human   239 YTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERD-----KFA 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11703	NP_650792.1	Na_K-ATPase	40..267	CDD:471796	58/289 (20%)
ATP1B2	NP_001669.3	Na_K_ATPase_bet	2..289	CDD:273446	62/305 (20%)
		immunoglobulin-like	193..290		20/94 (21%)