DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vib and pitpnc1

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001039199.1	Gene:	pitpnc1 / 734057	XenbaseID:	XB-GENE-959703	Length:	329	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	108/263 - (41%)
Similarity:	162/263 - (61%)	Gaps:	13/263 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIKEFRVTLPLTVEEYQVAQLFSVAEASKENTGGGEGIEVLKNEPFEDFPLLGGKYNSGQYTYK 65
            |.:||:|:.:|||||||::.||:.:::.|.|.:..|||:||::|||:|| |:.|    .||.|.|
Frog     1 MLLKEYRICMPLTVEEYRIGQLYMISKHSHEQSERGEGVEVVQNEPYED-PVHG----QGQLTEK 60

  Fly    66 IYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTVD 130
            ..:|.||:|::.|.:.|| ...:.|:|||.|||..|..| ..::.| |.|.|.::: |::.|:.|
Frog    61 RVYLNSKLPSWARAVVPK-IFYVTEKAWNYYPYTITEYT-CSFLPK-FSIHIETKY-EDNKGSND 121

  Fly   131 NVHELTPDKLKVREIVHIDIANDPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKKHVNPVMTCY 195
            |:.| :..|...|||..:|||.|.:....||..|||..:.|:|||||.| ...|::...|:|..|
Frog   122 NIFE-SEAKDAEREICFVDIACDEIPERYYKESEDPKNFVSEKTGRGQL-KEGWREAQEPIMCSY 184

  Fly   196 KLVTCEFKWFGLQTRVENFIQKSERRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKEELDKAR 260
            |||..:|:.:|||:|||.|:.|..|.:....|||.|...|.||.:||:::|..|..|:|..:  |
Frog   185 KLVAVKFEVWGLQSRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREYERTTQEATN--R 247

  Fly   261 QVG 263
            ::|
Frog   248 KIG 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	105/258 (41%)
pitpnc1	NP_001039199.1	SRPBCC_PITPNC1_like	2..250	CDD:176899	106/260 (41%)
pitpnc1	NP_001039199.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	267..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D951268at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920