DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vib and Lpin2

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001158357.1	Gene:	Lpin2 / 64898	MGIID:	1891341	Length:	931	Species:	Mus musculus

Alignment Length:	282	Identity:	57/282 - (20%)
Similarity:	93/282 - (32%)	Gaps:	84/282 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIKEFRVTLP-LTVE--------------------EYQVAQLFSVAEASKENTGGGEGIEVLKN 44
            :.::.|:.:|| .|||                    |..:.||....|...|            .
Mouse   564 LSLQVFQKSLPKATVESWVKDKMPKKSGRWWFWRKKESMIKQLPETKEGKSE------------V 616

  Fly    45 EPFEDFPLLGGKYNSGQYTYKIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYM 109
            .|..|.|     .|:.:.|       |..||.....:.:||.|: ||:....|.....:::.|..
Mouse   617 PPANDLP-----SNAEEPT-------SARPAENDTSSDEGSQEL-EESIKVDPITVETLSHCGTA 668

  Fly   110 DKNFKIDIYSQHIE----NDLGTVDNVHELTPD---KLKVREIVHIDIANDPVLPADYKPDEDPT 167
            .....:.:.|..|.    :| |..|.|..:|..   ..:....:::...||.|:.:|.    |.|
Mouse   669 SYKKSLRLSSDQIAKLKLHD-GPNDVVFSITTQYQGTCRCAGTIYLWNWNDKVIISDI----DGT 728

  Fly   168 TYQSKKTGR-GPLVGSDWKKH--------VNPVMTCYKLVTCEFKWFGLQTRVENF--------- 214
            ..:|...|: .|.:|.||...        :|.  ..||.:.|..:..|:......:
Mouse   729 ITKSDALGQILPQLGKDWTHQGIARLYHSINE--NGYKFLYCSARAIGMADMTRGYLHWVNDKGT 791

  Fly   215 ------IQKSERRLFTNFHRQV 230
                  :..|...||:.|||:|
Mouse   792 ILPRGPLMLSPSSLFSAFHREV 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	57/281 (20%)
Lpin2	NP_001158357.1	Lipin_N	39..144	CDD:282436
		Lipin_mid	504..594	CDD:293481	6/29 (21%)
		LNS2	672..897	CDD:285447	31/149 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900