DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vib and PITPNM2

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_024304866.1	Gene:	PITPNM2 / 57605	HGNCID:	21044	Length:	1435	Species:	Homo sapiens

Alignment Length:	264	Identity:	116/264 - (43%)
Similarity:	169/264 - (64%)	Gaps:	15/264 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIKEFRVTLPLTVEEYQVAQLFSVAEASKENT-GGGEGIEVLKNEPFEDFPLLGGKYNSGQYTY 64
            |.|||:|:.||:|||||::|||:.:.:.|:..| |.|.|:|:|:|.|:.|.|  ||   |||||:
Human     1 MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETYGEGSGVEILENRPYTDGP--GG---SGQYTH 60

  Fly    65 KIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTV 129
            |:||:...:|::.|.:.||.:|.:.||:||||||.||..|.| :::| |.|||.:.: :.|.|..
Human    61 KVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCP-FVEK-FSIDIETFY-KTDAGEN 122

  Fly   130 DNVHELTPDKLKVREIVHIDIANDPVLPADYKPDEDPTTYQSKKTGRGPLVGSDW----KKHVNP 190
            .:|..|:|.:.....|..|||..|||...:||.:|||..:||.||.|||| ..:|    ||.|.|
Human   123 PDVFNLSPVEKNQLTIDFIDIVKDPVPHNEYKTEEDPKLFQSTKTQRGPL-SENWIEEYKKQVFP 186

  Fly   191 VMTCYKLVTCEFKWFGLQTRVENFIQKSE-RRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKE 254
            :|..|||...||:::|:|:::|.||..:. ||:....|||.:|..|.||||:||:||.:|.:.:.
Human   187 IMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLSMENIRELEKEAQL 251

  Fly   255 ELDK 258
            .|.:
Human   252 MLSR 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	115/263 (44%)
PITPNM2	XP_024304866.1	SRPBCC_PITPNM1-2_like	1..258	CDD:176898	116/264 (44%)
		DDHD	718..1048	CDD:308481
		LNS2	1194..1325	CDD:197870
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810