DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vib and pitpnb

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_957214.2	Gene:	pitpnb / 393894	ZFINID:	ZDB-GENE-040426-895	Length:	272	Species:	Danio rerio

Alignment Length:	274	Identity:	162/274 - (59%)
Similarity:	205/274 - (74%)	Gaps:	15/274 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IKEFRVTLPLTVEEYQVAQLFSVAEASKENTGGGEGIEVLKNEPFEDFPLLGGKYNSGQYTYKIY 67
            |||:||.||.:||||||.||||||||||..||||||||||||||:|.      :...||||:|||
Zfish     4 IKEYRVVLPCSVEEYQVGQLFSVAEASKNETGGGEGIEVLKNEPYEK------EGEKGQYTHKIY 62

  Fly    68 HLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTVDNV 132
            ||:||||.:::::||:|:|..||:|||||||||||:||. ||..:|.|.|.:.| :.|.|.::||
Zfish    63 HLKSKVPGFVKMIAPEGALVFHEKAWNAYPYCRTIVTNE-YMKDDFMIKIETWH-KPDTGALENV 125

  Fly   133 HELTPDKLKVREIVHIDIAN-DPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKKHV-----NPV 191
            |:|.|...|..|:||||||: ..|.|.||||:|||..:.|:||||||| |.||||.:     :|.
Zfish   126 HDLDPITWKTVEVVHIDIADRSQVEPGDYKPEEDPEIFHSEKTGRGPL-GPDWKKELLAKPDSPR 189

  Fly   192 MTCYKLVTCEFKWFGLQTRVENFIQKSERRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKEEL 256
            |..|||||.:|||:||||::||||.|.|:|:|||||||:||..|.|..|||||||.:|::|:.||
Zfish   190 MCAYKLVTVKFKWWGLQTKIENFIHKQEKRIFTNFHRQLFCWIDNWVELTMEDIRRMEEETQREL 254

  Fly   257 DKARQVGEVRGMRA 270
            ::.|:.|:|||..|
Zfish   255 EELRKTGQVRGTSA 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	156/263 (59%)
pitpnb	NP_957214.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	307	1.000	Domainoid score	I1325
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4533
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2471
OMA	1	1.010	-	-		QHG54293
OrthoDB	1	1.010	-	-		D522789at33208
OrthoFinder	1	1.000	-	-		FOG0002025
OrthoInspector	1	1.000	-	-		otm24569
orthoMCL	1	0.900	-	-		OOG6_103092
Panther	1	1.100	-	-	LDO	PTHR10658
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4220
SonicParanoid	1	1.000	-	-		X1329
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870