DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vib and Pitpnm1

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_038939635.1	Gene:	Pitpnm1 / 361694	RGDID:	1306710	Length:	1263	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	113/282 - (40%)
Similarity:	166/282 - (58%)	Gaps:	35/282 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIKEFRVTLPLTVEEYQVAQLFSVAEASKENTGG-GEGIEVLKNEPFEDFPLLGGKYNSGQYTY 64
            |.|||:.:.||::::|||||||:.:.:.|:|.:.| |.|:|:|.|.|:.|.|  ||   :||||:
  Rat     1 MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGP--GG---NGQYTH 60

  Fly    65 KIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTV 129
            |:||:.|.:|.:.|.|.||.:|::.||:||||||.||..|.| :::| |.|:|.:.::. |.|..
  Rat    61 KVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCP-FVEK-FSIEIETYYLP-DGGQQ 122

  Fly   130 DNVHELTPDKLKVREIVHIDIANDPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKK---HVNPV 191
            .||..|:..:.:.|.:..|||..|.|.|.:||.:|||..|:|.||||||| ..||.:   ...|:
  Rat   123 PNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYRSVKTGRGPL-ADDWARTAAQTGPL 186

  Fly   192 MTCYKLVTCEFKWFGLQTRVENFIQKSE----------------------RRLFTNFHRQVFCST 234
            |..|||...||:::|:|.::|.||...:                      ||:....|||.:|..
  Rat   187 MCAYKLCKVEFRYWGMQAKIEQFIHDVDKDTEFRERCRLPCNAFGKSTGLRRVMLRAHRQAWCWQ 251

  Fly   235 DRWYGLTMEDIRAIEDQTKEEL 256
            |.|..|:|.||||:|::|...|
  Rat   252 DEWIELSMADIRALEEETARML 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	112/281 (40%)
Pitpnm1	XP_038939635.1	SRPBCC_PITPNM1-2_like	1..278	CDD:176898	113/282 (40%)
		DDHD	708..898	CDD:397132
		LNS2	1042..1173	CDD:197870
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810