DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vib and Lpin1

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_038968123.1	Gene:	Lpin1 / 313977	RGDID:	1307646	Length:	999	Species:	Rattus norvegicus

Alignment Length:	305	Identity:	57/305 - (18%)
Similarity:	102/305 - (33%)	Gaps:	90/305 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIKEFRVTLP-----------LTVEEYQVAQLFSVAEASKEN--------TGG-------GEGI 39
            :.::.|:..||           |....:.::::||...|:.|:        .||       |..
  Rat   607 LAMQAFQKPLPKSSCLSYLHMILDAIRFCLSKIFSPPTATVESIMRDKMPKKGGRWWFSWRGRN- 670

  Fly    40 EVLKNEPFEDFPLLGGKYNSGQ------YTYKIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPY 98
            ..:|.|...:..|.|..:|:|:      .|.:|.|..|..........|..|..:
  Rat   671 ATIKEESKPEQGLPGKGHNTGEQPAQLGLTTRIKHESSSSDEEHSATKPSSSSHL---------- 725

  Fly    99 CRTIITNPGYMDKNFKI---DIYSQHIENDLGTVDNVHELTPD---KLKVREIVHIDIANDPVLP 157
              ::::|..| .|..::   .:.|..::|  |..|.|..:|..   ..:....:::...:|.|:.
  Rat   726 --SLLSNVSY-KKTLRLTSEQLKSLKLKN--GPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVII 785

  Fly   158 ADYKPDEDPTTYQSKKTGR-GPLVGSDW------KKHVNPVMTCYKLVTCEFKWFGLQTRVENFI 215
            :|.    |.|..:|...|. .|.:|.||      |.:.......||.:.|..:..|:......::
  Rat   786 SDI----DGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYL 846

  Fly   216 QKSERR---------------LFTNFHRQVF----------CSTD 235
            .....|               ||:..||:|.          |.||
  Rat   847 HWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTD 891

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	57/304 (19%)
Lpin1	XP_038968123.1	Lipin_N	50..156	CDD:398325
		Lipin_mid	547..664	CDD:407117	10/56 (18%)
		LNS2	735..960	CDD:400509	32/163 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900