DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vib and Pitpnm2

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_038945373.1	Gene:	Pitpnm2 / 304474	RGDID:	1310867	Length:	1385	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	117/266 - (43%)
Similarity:	173/266 - (65%)	Gaps:	19/266 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIKEFRVTLPLTVEEYQVAQLFSVAEASKENT-GGGEGIEVLKNEPFEDFPLLGGKYNSGQYTY 64
            |.|||:|:.||:|||||::|||:.:.:.|:..| |.|.|:|:|:|.|:.|.|  ||   |||||:
  Rat     1 MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETYGQGSGVEILENRPYTDGP--GG---SGQYTH 60

  Fly    65 KIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTV 129
            |:||:...:|.:.|.:.||.:|.:.||:||||||.||..|.| :::| |.|||.:.: :.|.|..
  Rat    61 KVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCP-FVEK-FSIDIETFY-KTDTGEN 122

  Fly   130 DNVHELTPDKLKVREIVH--IDIANDPVLPADYKPDEDPTTYQSKKTGRGPLVGSDW----KKHV 188
            :||..|:|  ::..:::.  |||..|||.|::||.:|||..:||.||.|||| ..:|    ||.:
  Rat   123 NNVFNLSP--VEKNQLITDIIDIVKDPVTPSEYKTEEDPKLFQSIKTRRGPL-SENWIQEYKKRL 184

  Fly   189 NPVMTCYKLVTCEFKWFGLQTRVENFIQKSE-RRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQT 252
            .|:|..|||...||:::|:|:::|.||..:. ||:....|||.:|..|.|||||||.||.:|.:.
  Rat   185 LPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLTMEKIRELEKEV 249

  Fly   253 KEELDK 258
            :..|.:
  Rat   250 QLMLSR 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	116/265 (44%)
Pitpnm2	XP_038945373.1	SRPBCC_PITPNM1-2_like	1..258	CDD:176898	117/266 (44%)
		DDHD	704..998	CDD:397132
		SMP2	<1041..>1190	CDD:227415
		LNS2	1144..1275	CDD:197870
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810