DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vib and Pitpna

DIOPT Version :9

Sequence 1:	NP_001262726.1	Gene:	vib / 42306	FlyBaseID:	FBgn0267975	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_032876.1	Gene:	Pitpna / 18738	MGIID:	99887	Length:	271	Species:	Mus musculus

Alignment Length:	275	Identity:	164/275 - (59%)
Similarity:	208/275 - (75%)	Gaps:	14/275 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IKEFRVTLPLTVEEYQVAQLFSVAEASKENTGGGEGIEVLKNEPFEDFPLLGGKYNSGQYTYKIY 67
            :||:||.||::|:||||.||:|||||||..||||||:|||.|||:|...  |.|   ||||:|||
Mouse     4 LKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDD--GEK---GQYTHKIY 63

  Fly    68 HLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTVDNV 132
            |||||||.::|:|||:|:|.|||:||||||||||:|||. ||.::|.|.|.:.| :.||||.:||
Mouse    64 HLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNE-YMKEDFLIKIETWH-KPDLGTQENV 126

  Fly   133 HELTPDKLKVREIVHIDIAN-DPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKKH-VN----PV 191
            |:|.|:..|..|.::||||: ..||..|||.:|||..::|.||||||| |.:||:. ||    |.
Mouse   127 HKLEPEAWKHVEAIYIDIADRSQVLSKDYKAEEDPAKFKSVKTGRGPL-GPNWKQELVNQKDCPY 190

  Fly   192 MTCYKLVTCEFKWFGLQTRVENFIQKSERRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKEEL 256
            |..|||||.:|||:|||.:|||||.|.|:|||||||||:||..|:|..|||:|||.:|::||.:|
Mouse   191 MCAYKLVTVKFKWWGLQNKVENFIHKQEKRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQL 255

  Fly   257 DKARQVGEVRGMRAD 271
            |:.||...|:||.||
Mouse   256 DEMRQKDPVKGMTAD 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vib	NP_001262726.1	SRPBCC_PITPNA-B_like	2..261	CDD:176897	157/263 (60%)
Pitpna	NP_032876.1	SRPBCC_PITPNA-B_like	3..260	CDD:176897	157/263 (60%)
Pitpna	NP_032876.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..271		11/20 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	308	1.000	Domainoid score	I1336
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	322	1.000	Inparanoid score	I2490
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54293
OrthoDB	1	1.010	-	-		D522789at33208
OrthoFinder	1	1.000	-	-		FOG0002025
OrthoInspector	1	1.000	-	-		otm44156
orthoMCL	1	0.900	-	-		OOG6_103092
Panther	1	1.100	-	-	O	PTHR10658
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4220
SonicParanoid	1	1.000	-	-		X1329
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.870