DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cry and si:ch1073-390k14.1

DIOPT Version :9

Sequence 1:	NP_732407.1	Gene:	cry / 42305	FlyBaseID:	FBgn0025680	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	XP_009291670.1	Gene:	si:ch1073-390k14.1 / 101883856	ZFINID:	ZDB-GENE-141215-14	Length:	813	Species:	Danio rerio

Alignment Length:	554	Identity:	141/554 - (25%)
Similarity:	231/554 - (41%)	Gaps:	120/554 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VIWFRHGLRLHDNPALLAALADKDQGIALIPVFIFDG---ESAG-TKNVGYNRMRFLLDSLQDID 68
            |:|||..||:.|||||:..|   :.|..:||||:::.   |..| |.:.|.....:|..:|.
Zfish   187 VLWFRRDLRMWDNPALIGCL---ELGAPVIPVFLWNAMEEEGPGVTMSTGGASKYWLHQALV--- 245

  Fly    69 DQLQAATDGRG-RLLVFEGEPAYI--FRRLHEQVRLHRICIEQDCEPIWNERDESIRSLCRELNI 130
             .|:.:.:.|| .|:..:.||:.:  .:.|.::.....:......||...|||:::.....:..:
Zfish   246 -SLKRSLEERGSHLVTLKAEPSSLTALQGLMDETGAASVVATALYEPWLKERDDALWETLEKRGV 309

  Fly   131 DFVEKVSHTLWDPQLVIETNG----GIPPLTYQMFLHTVQI-----IGLP-------PRPTADAR 179
            ......|:.|.|| ..:.|.|    ||..:::  |:...|.     :|.|       |.|:|
Zfish   310 TCHIYHSYCLRDP-YTVSTRGVGLRGIGSVSH--FMSCCQQNPAGGLGSPLDAPTTLPSPSA--- 368

  Fly   180 LEDATFVELDPEFCRSLKL-FEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERLKVEQH 243
                     .|:.|....| ..::|..:...|          |:|.....:.....:|.......
Zfish   369 ---------WPQGCPLADLGLARMPRRKDGTV----------IDWAVDIRKTWDFSEEGAHTHLE 414

  Fly   244 AFER-GFYLPNQALPNIHDSPKS--MSAHLRFGCLSVRRFYWSVHDLFKNVQLRACVRGVQMTGG 305
            ||.| |.|...:..... |:|.:  :|.:|.||.||.|:..|:             .||.:.. .
Zfish   415 AFLRDGVYRYEKESCRA-DAPNTSCLSPYLHFGQLSARQVLWA-------------ARGARCK-S 464

  Fly   306 AHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAK---PNENL--------LQSWRLGQTG 359
            .....:|.||:..|......|:            :||..   |.:.|        |::|:.|:||
Zfish   465 PKFQRKLAWRDLAYWQISLFPD------------LPWESLRPPYKALRWSSDHAHLKAWQRGRTG 517

  Fly   360 FPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWM--- 421
            :||:|.|||||...||:::.:|:.||:||. ..|...|:.|.:.|...|:|||.::.|..|.
Zfish   518 YPLVDAAMRQLWQTGWMNNYMRHVVASFLI-AYLHFPWQEGYRWFQDTLVDADVAIDAMMWQNGG 581

  Fly   422 ------WVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQ 480
                  |            :.|..|:..|...||.||:::|:.|||..:|.:.:|:||:......
Zfish   582 MCGLDHW------------NFVMHPIDAALTCDPCGTFVRQWCPELKALPDDLIHKPWKCPTSML 634

  Fly   481 EQYECLIGVHYPERI-IDLSMAVKRNMLAMKSLR 513
            .:...:.|..||||| |||.....:::..:.|:|
Zfish   635 RRAGVVFGDSYPERIVIDLEERRAQSLQDVASVR 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cry	NP_732407.1	PhrB	4..504	CDD:223492	139/543 (26%)
		DNA_photolyase	8..175	CDD:279247	48/189 (25%)
		FAD_binding_7	310..510	CDD:281440	64/220 (29%)
si:ch1073-390k14.1	XP_009291670.1	PhrB	185..662	CDD:223492	139/546 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0415
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378952at2759
OrthoFinder	1	1.000	-	-		FOG0000663
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2229
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850